That $145/ton DDGS you’re feeding? Contains the same compounds as $20K/ton supplements. Your cows knew. Now you do too.

EXECUTIVE SUMMARY: That pile of DDGS you’re feeding at $145/ton contains the same immune-boosting compounds as supplements costing $20,000/ton—you just didn’t know it. University research reveals that distillers grains carry billions of heat-killed yeast cells packed with beta-glucans, potentially improving transition cow health and colostrum quality. Producers already report fewer metabolic issues and stronger calves when feeding DDGS, though they’ve been crediting the protein content. For a 500-cow dairy, these hidden benefits could be worth $42,900 annually. The catch: we can’t reliably test for these compounds yet, and every ethanol plant produces different levels. Until standardization develops over the next 3-5 years, you’re essentially feeding a lottery ticket—valuable, but unpredictably so.

I was having coffee with a group of nutritionists last month when someone brought up something interesting. “We’ve been feeding distillers grains for twenty years,” one of them said. “But are we really understanding what’s in them?”

You know, that question has been rattling around in my head ever since. Because what we’re starting to discover about DDGS might change how we think about this everyday feed ingredient—and maybe even how we evaluate feed efficiency in general.

The Research That’s Getting Everyone Talking

This year, new university-led research and field studies have begun examining how dried distillers grains affect the health of transition cows and calves. While early results suggest possible improvements in colostrum and calf immunity, producers should remember that more peer-reviewed research is needed before making major feeding changes.

Here’s what’s interesting: it might not just be about the protein and energy we usually focus on.

You probably know the basics of how DDGS are made—corn is fermented with yeast, the alcohol is removed as ethanol, and what’s left is dried and sold to us as feed. What I hadn’t really thought about until recently is that all those yeast cells used in fermentation? They’re still in there. Heat-killed from the drying process, sure, but their cell walls are intact.

And those cell walls… well, according to feed chemistry research from places like Cornell and Wisconsin, they contain compounds like beta-glucans and mannanoligosaccharides. If those sound familiar, it’s because they’re the same things that companies have been selling us in premium yeast supplements for years. The difference is, in DDGS, they just come along as part of the package.

Looking at the Numbers

What I’ve found particularly thought-provoking is when feed scientists analyze DDGS for these yeast components. Preliminary industry and university analyses estimate that the beta-glucan content in DDGS may range from 3 to 6 percent, though results vary widely by plant and region.

Now, think about this for a minute. Many of us are spending around $20 to $25 per cow on various transition supplements—that’s based on current extension budgets from Penn State and Wisconsin. Between anionic salts, yeast cultures, protected choline, trace minerals… it adds up. I was talking with a producer from northeast Wisconsin recently who calculated he’s at about $22 per cow through the transition period. Pretty typical for folks who are serious about fresh cow management.

Meanwhile, we’re feeding DDGS at maybe 10 to 15 percent of the dry cow ration, chosen mainly because they’re economical when soybean meal gets pricey. But what if those distillers grains are doing more than we realize?

Some university field trials and producer observations suggest there might be something to this, though—and I want to be clear here—we’re still in the early stages of understanding exactly what’s happening. The mechanisms aren’t fully worked out yet. But anecdotally, producers and some university field trials have noted possible improvements in colostrum quality or calf health when DDGS are used, though comprehensive published research is still underway.

What Producers Are Noticing

This is where it gets really interesting. I’ve been making a point of asking producers about their experiences with DDGS in transition diets, and I keep hearing similar themes.

A friend who runs about 400 cows in southwestern Minnesota told me, “Our fresh cows just seem to handle the transition better when DDGS are consistent in the closeup ration. Fewer DAs, better appetites coming out of calving.” He’d always figured it was the extra energy or maybe the bypass protein.

I heard something similar from a larger operation in California’s Central Valley, and even a grazing dairy in Vermont mentioned that its calves seem more vigorous when DDGS are higher during the dry period. Up in the Northeast, where they’re dealing with different forage bases than we see in the Midwest, producers are still noticing these patterns.

A producer near Syracuse, New York, who’s been tracking this closely, mentioned something interesting: “We started monitoring colostrum quality more carefully last year. The weeks when DDGS inclusion was higher, our Brix readings seemed better. Could be a coincidence, but it’s got me thinking.”

Now, these are just observations—not controlled research. Every farm has so many variables at play, and we can’t draw firm conclusions from field observations. But when you hear the same things from different types of operations in different parts of the country… it makes you wonder, doesn’t it?

The Economics of It All

Let’s talk dollars and cents, because that’s what matters at the end of the day.

With current Midwest pricing from USDA reports—and you know how this changes—DDGS are running somewhere around $145 to $165 per ton, depending on your contracts and location. Soybean meal? We’re looking at $420 to $450,based on recent DTN spot prices. The economics of protein are pretty clear, which is why so many of us use these ethanol coproducts.

But here’s a thought: what if there’s additional value we haven’t been accounting for in our feed efficiency calculations?

I was working through some numbers with a nutritionist colleague, and even if—and this is purely hypothetical—standardized DDGS with guaranteed bioactive content commanded a $75 per ton premium, the math could still work when you consider potential reductions in other supplements.

Of course, that market doesn’t exist yet. And honestly, it might never fully develop given all the challenges involved.

Why This Isn’t Going to Be Simple

Before anyone gets too excited and starts changing their rations, we need to talk about the real-world challenges here.

The biggest issue? Variability. That estimated 3-6% range in beta-glucan content I mentioned? That’s a problem if you’re trying to formulate consistent rations.

And it’s well documented by groups like the U.S. Grains Council that different ethanol plants use different corn, different yeast strains, and different drying temperatures. All of that affects what ends up in your feed bunk. I was talking with a producer in Illinois who sources from three different ethanol plants depending on pricing and availability. He said the physical characteristics alone vary noticeably—color, smell, texture. If the basics vary that much, imagine the variation in these bioactive compounds we’re talking about.

Testing is another bottleneck. While there are methods to measure these compounds, they’re not something you can get from your regular feed testing lab. Most commercial labs still focus on crude protein and fiber analysis. I’ve checked with several major labs, and while they’re aware of the interest, they haven’t seen enough demand yet to add these bioactive analyses. Maybe that’ll change, but we’re not there yet.

And then there’s the regulatory side. According to the FDA Center for Veterinary Medicine and AAFCO guidelines for animal feed, companies must be very careful about health claims. An ethanol plant can’t just start marketing their DDGS as “immune-supporting” without crossing into regulated territory. They’re limited to talking about composition, not function.

What This Means for Your Operation Today

So, where does this leave us as dairy producers?

Well, first off, you can’t call up your feed dealer today and order “high-beta-glucan DDGS.” That’s not a thing yet. But understanding that DDGS might be delivering benefits beyond just protein and energy—that’s worth considering in your dairy nutrition strategy.

Here’s what I’ve been telling folks who ask about this:

Don’t change everything based on preliminary research. DDGS are still a good deal based on their traditional nutritional value alone. That hasn’t changed.

But maybe start paying closer attention. Track what happens when DDGS inclusion changes in your rations. Watch your colostrum Brix readings. Keep an eye on fresh cow health events. You might already be seeing patterns you haven’t connected.

If you can, try to source from consistent suppliers. While you can’t specify bioactive content, ethanol plants with good process control probably have more consistent products overall. A large dairy I know in Nebraska has been doing this for years—not for these functional properties we’re discussing, but just for ration consistency. Makes sense either way.

And think about where in your feeding program DDGS might offer the most value. If these functional benefits are real, transition cows would be the logical place to focus. That’s where immune support and colostrum quality matter most for long-term herd health.

Most importantly, work with your nutritionist on this. Any changes to your feeding program need to fit into your overall strategy, not work against it.

The Bigger Picture Here

What fascinates me about all this is what it says about how we evaluate feeds in general.

For decades, we’ve focused on the measurable nutrients—protein, energy, fiber, minerals. Our formulation software is really good at modeling these. But what if there’s a whole category of bioactive compounds that influence health and productivity through different pathways? Compounds we’re not routinely measuring or accounting for?

Think about it—forages have polyphenols, fermented feeds have metabolites from bacterial activity. Even regular corn silage might have functional compounds we don’t consider.

Someone made an interesting comparison at a conference recently: we might be where we were with vitamins a century ago—knowing something important is there, but not having all the tools yet to understand or use it fully.

Looking Down the Road

The dairy industry has always moved forward through careful observation, good science, and practical application. This emerging understanding about DDGS fits right into that pattern.

Will this completely change how we feed cows? Probably not. But it might add another layer to our decision-making, especially for specific times like the transition period, where these functional benefits could really matter.

We definitely need more research. Those early university findings need to be replicated and expanded. We need better, practical, affordable testing methods. And ultimately, we need larger field trials to see if these effects hold up on commercial farms.

The good news is, this work is happening. Universities have projects underway. Feed testing labs are exploring new methods as demand develops. Even some ethanol producers are starting to think differently about their product.

And it’s worth noting—this isn’t just a U.S. conversation. International markets from Mexico to Southeast Asia import substantial amounts of American DDGS. If functional properties become a selling point, that could reshape global trade patterns. European feed companies are already exploring bioactive feed ingredients more aggressively than we are in some cases.

What’s the timeline for all this? Hard to say exactly, but based on how these things typically unfold in our industry, I’d guess we’re looking at 3 to 5 years before we see meaningful market changes—if they happen at all. That’s about how long it takes for research to build up, testing infrastructure to develop, and markets to adjust.

What’s encouraging to me is that we’re not talking about adding expensive new ingredients. We’re talking about potentially getting more value from something we’re already feeding. In an industry where margins are always tight, finding hidden value in what we’re already doing… that could make a real difference.

The Bottom Line

You know, the cows probably figured this out before we did. They usually do, don’t they? They’ve been getting whatever benefits DDGS offer while we focused on the protein and energy values.

Maybe that’s the real lesson here. Sometimes the best discoveries aren’t about finding something new—they’re about better understanding what’s been right in front of us. And in this case, it’s been sitting in feed bunks across North America for the better part of twenty years.

It makes you wonder what else we might be missing, doesn’t it? But then again, that’s what keeps this industry interesting. Just when you think you’ve got it all figured out, you learn something new that makes you look at things differently.

For now, keep feeding DDGS when they make economic sense. Pay attention to how your cows respond. Stay informed as this research develops. And always remember—the best feeding decisions are the ones that work for your specific operation, with your cows, in your situation.

Because at the end of the day, that’s what really matters. Not what might be in the feed, but how your cows perform with it. And if they’re doing well with DDGS at current prices? Well, any additional benefits we discover are just icing on the cake.

The next time you’re looking at that pile of DDGS getting mixed into the TMR, maybe take a second to think about what else might be in there. We might not fully understand it yet, but your cows seem to appreciate it either way.

KEY TAKEAWAYS:

• DDGS at $145/ton contain the same beta-glucans as $20,000/ton yeast supplements—you’ve been feeding premium immune support without knowing it
• Producers seeing fewer fresh cow problems with DDGS now have an explanation: 3-6% yeast-derived compounds supporting immunity and colostrum quality
• The math is compelling: $42,900 potential annual value for a 500-cow dairy, just from benefits you’re likely already getting
• Today’s move: Track colostrum Brix and transition health against DDGS inclusion—you might already see patterns worth thousands
• The catch: Without testing (3-5 years out) or standardization, you’re feeding a lottery ticket—valuable but unpredictable

Complete references and supporting documentation are available upon request by contacting the editorial team at editor@thebullvine.com.

Learn More:

• Why Smart Dairies Are Spending MORE on Feed at $4.20 Corn (And Banking $100K Extra) – Reveals how progressive dairies achieve better returns by investing in quality over cheap ingredients, demonstrating the economics behind strategic feed decisions that prioritize functional value over lowest cost per ton.
• Building a Beef-on-Dairy System: Capturing $360,000 in Annual Farm Profit – Provides strategies for maximizing calf value while maintaining herd health, showing how transition cow management and colostrum quality directly impact both dairy replacement and beef-cross calf profitability in today’s diversified markets.
• What’s Happening with the $2.7 Billion Hidden Loss in Our Dairy Herds – and How the Industry is Shifting – Explores emerging understanding of bacterial communication and subclinical health issues, demonstrating how functional feed ingredients like those in DDGS could address hidden losses through immune modulation rather than traditional treatment approaches.

Join the Revolution!

Join over 30,000 successful dairy professionals who rely on Bullvine Weekly for their competitive edge. Delivered directly to your inbox each week, our exclusive industry insights help you make smarter decisions while saving precious hours every week. Never miss critical updates on milk production trends, breakthrough technologies, and profit-boosting strategies that top producers are already implementing. Subscribe now to transform your dairy operation’s efficiency and profitability—your future success is just one click away.