It would be difficult to overstate the importance of the U.S. dairy industry. At $27 billion annually, its impact on the American economy and diet is immense, and at its core, the sector is completely dependent on the health and productivity of cows.
Americans drink more than 6 billion gallons of milk per year, and another 10 billion gallons are used to produce cheese, not to mention the milk that goes into products such as ice cream and yogurt. Yet, it’s safe to say, most consumers take the well-being of dairy cows for granted. But the country’s 65,000 dairy farmers don’t — they can’t afford to.
One of dairy farmers’ biggest concerns is the vulnerable and important period for the dairy cow that extends three weeks before and three weeks after calving. Her metabolic needs increase dramatically, and how she copes with this high-energy transition period influences how well she performs during the rest of the lactation.
During this “transition cow” period, diseases can result in milk yield decreases of 5 to 10 pounds per day at peak lactation, a considerable economic loss for the producer. And research has shown that there is a domino effect: when a cow suffers from one transition disease, she is more likely to develop another, such as mastitis, ketosis or postpartum metritis.
Field surveys done by Penn State Extension show that more than 50 percent of cows will experience one or more metabolic or infectious disease following calving.
So, dairy-nutrition researchers such as Penn State’s Alex Hristov have been experimenting with various dietary supplements to bolster the immune systems of transition cows. A professor of dairy nutrition in the College of Agricultural Sciences, he has concentrated on the effects of spicing up the diets of transition cows — feeding them phytonutrients and essential oils that are known to boost and support the immune systems of other species, including humans — and gauging the cows’ health response.
Phytonutrients and essential oils — bioactive compounds that act as antimicrobials and antiseptics — are not required by dairy animals, but ingesting the compounds could make cows healthier, according to Hristov. Some examples are allicin from garlic, thymol from thyme and oregano, capsaicin from hot peppers, eugenol from cloves, pinene from juniper berries, limonene from dill, cinnamonaldehyde from cinnamon, and curcumin from turmeric.
At first, Hristov and other animal scientists considered phytonutrients and essential oils as a way to improve or alter rumen fermentation with naturally occurring compounds rather than commercial additives or antibiotics. The objective in altering rumen fermentation is to reduce methane gas production and increase propionate and butyrate production, resulting in more efficient fermentation and reducing greenhouse gas emissions.
But in recent research, Hristov has been looking beyond the rumen. In a series of papers, including an invited review published this spring in the Journal of Dairy Science, he and postdoctoral scholar Joonpyo Oh focus on the intestinal effects of phytonutrients in dairy cows, especially capsicum oleoresin from chili peppers. Oh, who conducted the research as part of his doctoral thesis, concluded that phytonutrients appear to have positive physiological effects on the immune response in ruminants, and in lactating dairy cows in particular.
“The novel thing about this research is that we have shown that these phytonutrients can have downstream effects after the rumen,” Hristov said. “For the first time, we have shown that these compounds can bypass the rumen, which means they can avoid microbial degradation in the rumen. So they can be absorbed, through specific receptors, in the small intestine, which allows the cow to benefit from their physiological effects, including improvements in immunity, oxidative stress and insulin regulation.”
He explained that the regulatory effects of phytonutrients on “cytokines, acute phase proteins, blood immune cells, and oxidative stress status, including lipid peroxidation and endogenous antioxidants,” seem to be beneficial for immune suppression of inflammation disease in dairy cows.
Although more research is needed to confirm results of Penn State studies, Hristov believes phytonutrient supplements such as capsicum oleoresin in the feed of transition dairy cows could have an impact on the dairy industry. “The transition period is the most critical period in the life of a cow, so anything that can decrease metabolic diseases during that time could prove to be significant,” he said.
“Anything that improves animal health and immune response in these cows is important. And in previous studies we even saw an increase in milk production. That kind of direct impact, if proven, would be very important.”
Follow-on studies are unfolding in Hristov’s lab in collaboration with a Swiss company to develop a rumen-protected capsicum product to reliably deliver the benefits of phytonutrients to cows’ immune systems. Researchers are using capsicum oleoresin, Hristov noted, because after investigating other phytonutrient compounds, the peppers had “the most pronounced affect on cows’ health.”
But do cows like having their diet spiced up? “From the several experiments we conducted, they don’t seem to mind it,” Hristov said. “Cows consumed the ‘spicy’ diet the same as the control diet. Perhaps, like some of us, they like it.”
Source: PennState

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Metabolic and infectious diseases in transition dairy cows directly impact future milk production and reproductive performance. Metritis is an infectious disease that is typically observed 10 to 14 days after calving. Fresh cows with this infection have a foul smelling discharge and may or may not have a fever. Approximately 12% of freshening dairy cows experience some degree of metritis, with the incidence rate being greater in those that experience a difficult birth, have twins, or have a retained placenta. In a
Gone are the days when growth and health of dairy calves are the only important outcomes expected with successful calf management programs! We now understand that these programs also impact a calf’s future performance. Known as perinatal programming, management and nutritional practices during early life have three to seven times more influence on future milk production than sire selection. Our understanding in this area has increased in recent years and this will continue to be an actively studied area. Consequently, the role of certain management practices which control or impact future performance will become better understood along with a continual refinement of recommended nutritional and management practices in heifers prior to puberty. When implementing practices on farm, understanding the reasons behind these practices, why they have changed over time, and how they can impact future performance are important parts of managing heifer programs.
