Archive for Genetic Evaluation System – Page 2

New Genetic Evaluation For Cow Livabiliity

Breaking News ScreenWhen genetic evaluations for Productive Life (PL) were introduced by USDA’s Animal Improvement Programs Laboratory in 1994, U.S. dairy producers were handed an extraordinary opportunity to produce healthier cows. The good news is, it actually happened; when Predicted Transmitting Abilities (PTA) for Productive Life were incorporated into selection programs, the deterioration occurring in pregnancy rate for five decades (16 percentage points1) was soon reversed. In addition, genetic increases that were occurring in somatic cell score (SCS) that were revealed when PTA for SCS was initiated also were reversed and udder health improved as well. Now another genetic evaluation will be provided in August 2016 so producers will have a new tool to help even more. The new evaluation is PTA for Cow Livability (PTA C.LIV) which predicts cow’s transmitting ability to remain alive while in the milking herd. In contrast, PTA for Productive Life (PL) predicts transmitting ability for how long a cow is expected to remain in the milking herd before dying or being culled. Livability is just one of the several traits that determines Productive Life, yet one with a high economic influence that to date had not been accounted for adequately.

Populating US dairy herds with cows capable of longer productive life gave producers more opportunity for voluntary culling as they needed to dispose of fewer animals for health or management reasons. When a cow is sold for dairy or beef (voluntary or involuntary culling), the sale income is returned to the owner. In contrast, if a cow dies, or is euthanized as a consequence of ‘downer cow syndrome’, there is total loss of income. Just knowing which cows are likely to remain in the herd the longest is not the entire story. Instead, additional benefit comes from knowing which cows are likely to provide income at disposal. Because cow mortality rate averages 7% each lactation, death claims 20% of the U.S. cows while in the milking herd2. Conversely, 80% of cows remain alive permitting the producer to recoup their disposal income when they exit the herd. The lost ‘disposal income’ from current U.S. cows that will die is about $2.2 billion (20% × 9.2 U.S. million cows x $1200/cow) or $800 million per year.

Fortunately, in spite of the fact the heritability of mortality is low at 1.3%3, accuracy of PTA for Cow Livability is quite high as termination codes have been recorded in DHIA for decades. Over 92 million lactation records for 32 million cows have termination codes in the national database. As a result, genomic predictions having high accuracy can be derived for AI bulls for the new trait. Even the Reliability for young genomic tested bulls without daughters averaged 56%. Correlations between PTA for Cow Livability and PTAs for other traits have been calculated and vary considerably. For bulls having Reliability of 80% or higher, the correlation was 0.70 with Productive Life, 0.45 with Daughter Pregnancy Rate, but was rather low with the milk traits.

Cow Livability is defined such that if the cow died this lactation, the trait was set to 0%; if the cow lived through this lactation, it was set to 100%. To place it on a lifetime scale, the results are multiplied by 2.8 since average lactations per cow is 2.8. The table below show the average PTAs of animals that fall into the quintiles for Lifetime Net Merit $.

Table 1. Average PTAs of AI Holstein bulls with birthdates since January 1, 2000 for a number of traits* grouped by percentiles for Lifetime Net Merit Dollars (NM$).

Percentile NM$ PTAMilk PTAFat PTAProt PTADPR PTASCS PTAPL PTAC.LIV
80 to 99 +588 +1043 +52 +38 +1.3 2.2 +5.6 +2.1
60 to 79 +423 +944 +34 +30 +.9 2.2 +3.8 +1.4
40 to 59 +310 +612 +25 +22 +.4 2.2 +2.6 +.9
20 to 39 +197 +432 +18 +16 0 2.3 +1.4 +.2
0 to 19 -53 -164 -2 -2 -.8 2.4 -.8 -1.1

*PTA=Predicted Transmitting Ability, Prot=Protein, DPR=Daughter Pregnancy Rate, SCS=Somatic Cell Score, PL=Productive Life, C.LIV=Cow Livability

The top quintile of bulls for Net Merit Dollars had PTAC.LIV that averaged +2.1% while the bulls in the lowest quintile averaged -1.1%. This indicates the top quintile bulls will have about 3.2% more daughters that will not die during their milking life than will the lowest quintile bulls. Because the average of cow remaining alive throughout their entire milking life is 80%, a bull that is +2.1 is expected to have 82.1% of his daughters that remain alive while a bull from the lowest quintile is expected to average 78.9% (breed average of 80.0 – 1.1 = 78.9% that remain alive). This 3.2% difference in a 244 cow herd (the average DHIA herd size) would produce $9,400 in additional income.

Eventually the PTA for Cow Livability will be incorporated into all 4 lifetime merit indexes, but this will be completed after users become more familiar with the new trait. When this happens, the weight given to Productive Life is expected to decline from about 19 to 14%, and the emphasis assigned to Cow Livability will be near 7%. Thus, the total emphasis of cow longevity would increase to 21%.

Having Cow Livability is one more step toward adding value to the genetic information that will improve dairy producers’ profitability. Producers participating in DHIA can help to improve the reliability of this trait by accurately reporting the reasons why cows leave their herds.

Duane Norman works for the Council on Dairy Cattle Breeding; Janice Wright and Paul VanRaden are employees of USDA’s Animal Genomics and Improvement Laboratory.

1 Council of Dairy Cattle Breeding. 2016. Trend in Daughter Pregnancy Rate for Holstein or Red & White Calculated April 2016. Accessed June 1, 2016. https://www.cdcb.us/eval/summary/trend.cfm

2 Norman, H.D., L. M. Walton, and João Dürr. Reasons that cows in Dairy Herd Improvement programs exit the milking herd (2014). CDCD Res. Rpt. (16-02). 2016. (Popular Publication)

3 Miller, R.H., M.T. Kuhn, H.D. Norman, and J.R. Wright. Death losses for lactating cows in herds enrolled in Dairy Herd Improvement test plans. J. Dairy Sci. 91(9):3710-3715. 2008.

Relationships of Rump with Fertility & Calving Performance

The dairy cattle breeding world has long promoted the importance of structurally sound rumps. Proper rump conformation has been touted as a promoter of fertility and calving ease. In this article we take a closer look at these relationships as well as genetic selection to improve them.

The Impact of Rump – Cow Level

At Canadian Dairy Network (CDN), we used recent classification, calving and breeding data in for over 60,000 first lactation Holsteins to quantify any phenotypic relationships that may exist between rump conformation with measures of calving performance and fertility. Rump conformation is assessed on a linear scale from 1 to 9 for Rump Angle, Pin Width, Loin Strength and Thurl Placement, which are combined into an overall score for Rump. Calving performance is measured both as calving ease and calf survival, which is the opposite of stillbirth rate. Measures of each cow’s fertility include the interval from calving to first service/insemination and the subsequent interval from first service to conception, with the sum of these together equalling days open.

Results of the analysis at the cow level indicate that some relationships exist between classification scores for rump traits and performance at first calving:

  • Very low pins (Rump Angle of 8 or 9) are associated with 2% easier calvings compared to cows with very high pins (Rump Angle 1 or 2)
  • Thurls too far back (scores of 1 or 2) are associated with nearly 3% more difficult calvings compared to other linear scores
  • The rate of calf survival is 5% higher for cows with very strong loins (scores of 8 or 9) compared to very weak loins (scores of 1 or 2)
  • Calf survival is 3% higher for cows with very low pins (Rump Angle of 8 or 9) compared to very high pins (Rump Angle of 1 or 2)

Although very little relationship was found between rump conformation and the interval from calving to first service, Figure 1 shows the significant association found between Rump Angle, Pin Width and Thurl Placement on the cow’s fertility when measured as the interval from first service to conception.

For Pin Width, it is clear to see that cows with very narrow pins (linear scores of 1 or 2) have conception delayed by 4 days compared to cows with pins assessed with a score of 5. Cows with very wide pins in this analysis also showed a delay in conception of one day.

The Canadian classification system for Rump Angle and Thurl Placement considers these traits as having an intermediate optimum. Cows with a linear score of 5 or 6 for Rump Angle are deemed ideal and a score of 6 is ideal for Thurl Placement. Figure 1 clearly supports this concept of intermediate optimum for both these traits since cows with linear scores at either extreme demonstrated poor conception rates. For Rump Angle, cows with very high pins had conception delayed by nearly 3 days compared to cows with a linear score of 5 and cows with very low pins also experienced a delay of one day. For Thurl Placement, cows scored at either extreme of the linear scale had conception delayed by an average of 2 days compared to those with the ideal score of 6.

The Impact of Rump – Sire Level

As mentioned earlier, type classification data for the four descriptive traits are combined to assign each cow an overall Rump score.  This score is used to calculate sire proofs for Rump, which is the primary tool for genetic selection to improve rump conformation. Table 1 shows proof correlations between Rump and selected key traits derived using data from 4,100 domestically proven Holstein bulls. Positive correlations above 10% are identified in green while negative correlations below 10% are labeled in red.

From these results, we can draw the following conclusions:

  • The negative correlation with Calving Ability indicates that sires with high Rump proofs tend to produce calves that have greater difficulty being born and/or surviving.
  • Daughter Calving Ability and Daughter Fertility are genetically unrelated to Rump in terms of sire selection, meaning that selection for Rump will not translate into genetic progress for these functional traits.
  • The positive correlation between Rump and Herd Life indicates sire selection can improve both of these traits at the same time.
  • Rump is positively correlated with both LPI and Pro$ so selection for either of these national indexes will result is genetic progress for Rump at the same time.

The positive correlation between Rump and LPI is of particular interest since Rump is not a trait that is directly included in the Holstein LPI formula. The genetic relationship between Rump with other traits in the LPI formula already translates to genetic gain for Rump. While it is useful to record individual rump traits and monitor breed trends over time, direct inclusion of Rump in the LPI formula is unnecessary since ample improvement can be made by using either national index as a primary selection tool. As a herd management tool, the Canadian classification system for rump traits aims to identify cows that will have better fertility and calving performance.

If improving rumps are important to you, either on a herd or individual cow basis, selection for rump traits will help you achieve your goals. If improving fertility and calving performance is important to you, good management combined with selection directly for the Daughter Fertility, Daughter Calving Ability and Calving Ability will get you there.

Authors:
Lynsay Beavers, Industry Liaison Coordinator, CDN
Brian Van Doormaal, General Manager, CDN

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Pin Setting and Set of Rear Legs: Termination of Publication in Canada

The conformation assessment program in Canada has included Rump Angle and Rear Legs Side View in all breeds for over 30 years. These traits are assessed by classifiers using a linear scale from 1 to 9 whereby an intermediate score of 5 or 6 is ideal for Rump Angle and 5 is ideal for Rear Legs Side View (see relevant sections from the Conformation Analysis sheet for Holsteins below).

Given the manner in which these traits are assessed, genetic evaluations are expressed using letter designations to reflect the expected outcome of an animal’s progeny, on average.  For Rump Angle, genetic evaluation values other than zero include the letters of either “H” to reflect a tendency towards high pins or “L” for a tendency toward low pins. Letters for Rear Legs Side View are “S” for a tendency toward straight legs or “C” for curved legs. Sires with a proof of zero are expected to produce more daughters with the ideal score for these traits.

Accompanying the publication of Rump Angle and Rear Legs Side View, CDN has also used the same classification data to publish genetic evaluations for analogous traits, Pin Setting and Set of Rear Legs, respectively. These traits have been published by CDN to facilitate the interpretation of evaluations by producers using a “desirability” scale whereby higher values towards +15 reflected sires that were most likely to produce daughters with the ideal/desired rump angle and rear legs when viewed from the side. At its most recent meeting in May 2016, the CDN Board of Directors approved the recommendation from its advisory committee, the Genetic Evaluation Board (GEB), to cease the publication of evaluations for Pin Setting and Set of Rear Legs effective the genetic evaluation release in August 2016.  The main reasons for this decision include:

  • The publication of two sets of evaluations for essentially the same trait has not been well understood by producers and industry personnel
  • These traits, expressed on the “desirability” scale have the lowest values of estimated heritability among all conformation traits, ranging from 2 to 7%, and are significantly lower than heritability values for the analogous traits of Rump Angle and Rear Legs Side View.
  • Internationally, most other countries publish genetic evaluations for Rump Angle and Rear Legs Side View, which are included in the MACE evaluation services offered by Interbull. Canada is the only country worldwide that has also published Pin Setting and Set of Rear Legs using the “desirability” scale.
  • With the arrival of genomic evaluations, observed gains in accuracy of prediction have been among the poorest for Pin Setting and Set of Rear Legs, reducing the value of these traits in current selection strategies.

To carry out the approved action and terminate the publication of genetic evaluations for Pin Setting and Set of Rear Legs, CDN has established the following implementation plan:

  • Data files associated with the August 2016 genetic evaluation release will no longer have actual values in fields associated with these two traits.  All such data fields will contain default values, which will be -99 for the actual genetic evaluation for all animals.
  • File formats for the December 2016 genetic evaluation release will be modified by excluding all data fields associated with Pin Setting and Set of Rear Legs.  The new file formats will also be modified to include data fields associated with the new Metabolic Disease Resistance (MDR) index, which will be introduced at that time for the Holstein, Ayrshire and Jersey breeds.
  • The CDN web site has been changed, effective immediately, to no longer display the genetic evaluations for these two conformation traits.  This affects each animal’s Genetic Evaluation Summary page as well as the Type Evaluation Details page for proven sires in Canada.
  • Industry partner web sites are also welcome to cease displaying evaluations for Pin Setting and Set of Rear Legs, when convenient in advance or at the time of the August 2016 release.
  • AI organizations are expected to exclude these traits from any proof sheets or other promotional materials, as well as genetic mating programs, effective August 2016, if not already excluded.

As genetic evaluation services offered by CDN continue to expand by adding new traits, it is also important to review the value of existing traits from time to time. The decision to terminate the publication of Pin Setting and Set of Rear Legs is an outcome of such a review without reducing the value of the conformation assessment program in Canada that includes Rump Angle and Rear Legs Side View.

Authors:           Brian Van Doormaal, General Manager, CDN
Lynsay Beavers, Industry Liaison Coordinator, CDN

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A Q&A on DWP$ and WT$

The Dairy Wellness Profit $ and Wellness Trait $ indexes may have you wondering whether you should adjust your genetic plan to include this new information. Here we have answers to 14 questions to help you decide what’s best for your dairy to make the maximum genetic progress in the direction of your goals!

What is Dairy Wellness Profit $ (DWP$) and Wellness Trait $ (WT$?)

These are genetic indexes calculated by Zoetis from producer-recorded data, in herds that are genomic testing or have genomic tested in the past.

How is the WT$ index compiled?

WT$ is a combination of the Wellness Traits (Ketosis, Displaced Abomasum, Retained Placenta, Metritis, Mastitis and Lameness). This means it is an index analogous to a 0-100-0 index, with 100% weight on health traits. However, those weights are divided between the various Wellness traits that Zoetis calculates.

Do each of the Wellness Traits get their own evaluation?

Yes. They are then combined into a Wellness Trait $ index to combine the expected impact.

How is DWP$ compiled?

DWP$ is a genetic selection index that equates to a genetic plan of 34% Production – 56% Health – 10% conformation. This differs from TPI (46-28-26) and the overall NM$ index (43-41-16).

The breakdown of the weight on health is different as well. DWP$ puts 30% of the weight on WT$, leaving 26% for the CDCB evaluated health traits of PL, DPR, SCS, DSB, DCE, CCR, HCR.

Are the Wellness traits developed by Zoetis?

The WT$ calculation is not a new concept, as it was first published in 2004, however this is the first routine evaluation and first genomic prediction for those traits.

Did Alta test all bulls for DWP$ and WT$?

No, but we tested the sires that we predicted would do well on the respective indexes based on their health trait values and how they rank on a 34% Production-56% Health-10% Conformation index. We are listing the top ten DWP$ sires and top five WT$ bulls in each of three categories: G-Stars, FutureStars and daughter-proven sires.

What is Alta’s testing plan going forward?

This will be dependent on the feedback from the customers and the demand for this information. In the short-term we will continue to test those sires that rank well on a traditional 34-56-10 index.

How can we predict which sires will do well on these indexes?

Because the correlation between DWP$ and a traditional 34-56-10 index is very high, we can predict quite well which sires will rank well on the DWP$ index.

How do these Wellness traits compare to Productive life?

Productive life encompasses every reason an animal leaves the herd, and the length of time she is productive compared to herdmates.

The Wellness traits are some of the exact reasons cows may leave, but instead measure incidence of disease, not departure from the herd. Of course many cows are affected, but do not leave the herd. Therefore the Wellness traits measure different things than Productive Life, however there is obviously a strong relationship between PL and WT$, with a stated correlation of 0.41. The relationship gets stronger if the combination of PL, DPR, and SCS is used, reinforcing that all the health traits are related to each other.

How should you use this information?

It’s still as important as ever to create your own, customized genetic plan based on your goals and the situation on your dairy.

Our stance at Alta has always been that the most important part of setting a genetic plan is getting the correct amount of weight in each of the three ‘buckets’ for production, health, and conformation – based on the current situation and future goals for your dairy. Once your genetic plan is decided, changing which individual traits are emphasized within each bucket will have far less impact.

If you select sires based on TPI (46% Production-28% Health-26% Conformation) or NM$ (43-41-16), the current DWP$ weighting of 34-56-10 puts significantly more weight on health than those two indexes, at the cost of production and conformation.

If your current genetic plan is set at 70-30-0, changing to DWP$ as a selection goal would be analogous to changing from 70-30-0 to 34-56-0. That doesn’t mean the change is wrong – it is just a VERY significant change, which should only be made because your goals or situation have changed, not just because there are new traits available.

However, if your genetic plan is set at 50-50-0, moving some of the 50% weight on health, and putting it towards the wellness traits, is a much less drastic adjustment.

Changing the bucket weights in a genetic plan is always a strategic decision. Therefore, plans should change only when economics or the situation on your farm changes, not just because new traits become available.

Is there anywhere else to get information on these traits?

In Canada, CDN has been calculating an evaluation on clinical mastitis for some time now, and those evaluations are readily available. They are also collecting data on each of the other five traits, and expect to have evaluations available within the next year.

In the Netherlands, these traits are routinely collected and evaluated. In the US, the CDCB is currently evaluating the possibilities to do genetic evaluations for these traits.

What is the correlation between DWP$ and other indexes?

The correlation between TPI and DWP$ is 0.89. The correlation between NM and DWP$ is 0.92. The correlation between a 34-56-10 index calculated with Alta’s Bull Search or AltaGPS is 0.94.

Are the Wellness traits heritable, or driven more by management?

Many traits that are heavily influenced by environment still have a genetic component, and the Wellness traits are no different. While the heritability of these traits ranges from 6%-8%, they should not be eliminated from a selection plan simply because of low heritability. Daughter fertility, Productive Life, and other traits also have relatively low heritability, but many herds have made substantial genetic progress, and see real results for these traits through genetic selection.

What is the reliability of the Wellness Traits?

The reliability of the Wellness Traits is ~0.50.  This is relatively low compared to other traits that are routinely selected for. This means more re-ranking can occur between animals as more data is gathered.

Comparatively, the reliability of other CDCB health traits such as PL, DPR, and SCS is around .70 on young AI bulls because there is more historical data available for these traits.

Reliability is a measure of the precision of an estimate, and the likelihood that estimate changes over time. It is NOT how likely traits are to pass from one generation to the next.

Source: Alta Genetics

To view a listing of Alta’s top 10 DWP$ and top 5 WT$ sires, please Click HERE.

Managing Recessives & Haplotypes

Does it feel like dairy cattle breeding has gotten more complicated? Truthfully… in some ways it has. We now know about many genetic recessives and haplotypes that negatively affect profitability, and in the future, we’re sure to find more. In this article, learn how these genetic anomalies work, how their impact can vary from one herd to another, and how you can manage them effectively.

How do Recessives and Haplotypes Work?

An animal carries two copies of a gene or haplotype (i.e.: short section of DNA strand), one inherited from their dam and the other from their sire. An animal is said to be either “homozygous” for a gene or haplotype, meaning they inherited the same DNA section from both sire and dam, or “heterozygous”, meaning the DNA section inherited from the sire and dam are different. Heterozygous animals are usually referred to as “Carriers”. Most genetic anomalies in dairy cattle are controlled by genes that are recessive in nature, rather than dominant, which is the case of all of the known haplotypes affecting fertility as well as HCD, the haplotype associated with cholesterol deficiency. For genetic recessives, only homozygous animals, which have inherited two copies of the gene or haplotype, are affected.  For the fertility haplotypes, affected animals die from early embryonic loss while HCD results in early calf mortality.

Figure 1 illustrates the possible outcomes when two known carriers are mated together. Using HCD as an example, in this situation, 25% of offspring will be homozygous dominant (AA) and unaffected, 50% will be heterozygous (AB) and unaffected but able to pass on the recessive gene, while another 25% will be homozygous recessive (BB) and die, likely before weaning.

Breed Frequency versus Herd Frequency

Haplotypes affecting fertility work in the same manner outlined above, only a lost early pregnancy is the result. There are five haplotypes known to affect fertility in Holstein, two known in both Jersey and Brown Swiss, and one known in Ayrshire. These haplotypes are particularly of concern for coloured breeds as the percentage of carriers within breed tends to be high (10-25%), depending on the haplotype in question. In the Holstein breed, less than 5% of animals carry a haplotype affecting fertility. However, 12% of Holstein females are carriers of the more recently discovered, more costly, and more complex HCD.

Overall carrier frequencies can help paint a picture of the scale of a problem in a given breed. Carrier frequencies can, however, be highly variable from herd to herd, meaning a genetic recessive or haplotype can be much more impactful in one herd than another.  For example, Figure 2 shows the distribution of Holstein herds based on the average HCD carrier probability of the heifers and cows currently active in each herd. Although the overall frequency of HCD in Canadian Holsteins born in 2015 is 12%, we can see that many herds have higher frequencies and some are much higher! In fact, roughly 1,200 herds are made of at least 20% that are HCD carriers.

Herds made up of more carriers than average likely have a higher proportion of daughters sired by HCD carrier bulls listed in Table 1. If bloodlines listed in Tables 1 and 2 make up a significant portion of your herd, you’ll want to read on.

Managing Recessives and Haplotypes

CDN calculates Carrier Probability values for every animal in its database for all haplotypes and publicly displays them on the website as part of each animal’s “Pedigree” page. These values reflect the likelihood an animal carries a given haplotype and provide producers with the opportunity to manage these potentially problematic attributes in their herd. Strategies for managing genetic recessives and haplotypes could include:

  • Using an AI mating program that incorporates CDN carrier probabilities for recessives and haplotypes. Verify that your AI representative is avoiding mating potential/known carrier females to known carrier sires.
  • Determine potential carrier animals based on CDN carrier probabilities. Genomic test these animals to determine true carrier status. Subsequently, avoid mating carrier males to known carrier females. Again, this could be done with help from AI via a mating program that incorporates carrier probabilities since genotyped animals will have a probability of either “1%” (Free) or “99%” (Carrier).
  • Create a user account on the CDN website and subscribe to the Data Management Service called “Evaluations by Prefix”. Canadian breeders pay an annual subscription fee of $100 for access to query tools and files specific to their herd for the next 12 months. Recessive and haplotype carrier probabilities for all females, genotyped or not, are available for subscribers upon download of a detailed spreadsheet that can be opened with software like Excel. This file also contains genetic evaluations for all traits. When logged in, producers can run mates via the Inbreeding Calculator. The output file from this calculator contains a probability of being affected for all potential progeny of the mating, helping producers make more informed decisions.

Avoiding carrier sires altogether is not a recommended strategy. A sire remaining in AI despite a positive carrier status for any single genetic recessive or haplotype means his genetic offering likely outweighs the fact that he may pass on a recessive gene. These sires simply need to be used appropriately on females known to be non-carriers.

Negative genetic anomalies can be difficult to keep track of and add a new complexity to breeding dairy cattle. Utilize the strategies presented in this article to minimize their impact in your herd. CDN services are there to help you do exactly this.

Authors:
Lynsay Beavers, Industry Liaison Coordinator, CDN
Brian Van Doormaal, General Manager, CDN

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Who needs another index?

Have you asked yourself or a fellow breeder that question? Genetic or management indexes are created for at least one reason or purpose.  It seems like every AI unit has developed their own index for one purpose or another.  Here are some Bullvine thoughts on multi-trait genetic indexes that are designed to assist breeders in genetic improvement and marketing. These indexes are usually referred to as total merit indexes.

Others Use Indexes

Read any business article and you will not get far without reading about the Dow Jones or Consumer Price indexes. Both are designed for specific purposes. They are to reflect the price trends in a selected group of companies on the NY Stock Market, or prices consumers must pay for a selected basket of goods that they usually purchase. We regularly hear whether they are trending upwards in inflationary times or down when the economy is trending negative. However, indexes do not end with the economy. Think about it – personal health indexes, student performance indexes, and equipment performance indexes all part of what we have in our daily lexicon.

Why Total Merit Indexes?

In the 1980’s, dairy cattle marketers were claiming to have the #1 bull or #1 cow in their country or the world. #1 for type, #1 for milk, or #1 for fat % improvement. Even then total animal improvement focused breeders were asking which animals put the total package together. As opposed to being single trait wonders.

In response, breeds and genetic evaluation centres saw the need for indexes that combined, on an appropriately weighted basis, the traits in need of improvement. In the United States, combined indexes like TPI, NM$ and JPI were created, and they came into wide use by breeders in their selection and marketing. In Canada, the index, created by all organizations working together, was LPI. Other country total merit indexes included BW in New Zealand, RZG in Germany, ISU in France and NVI in the Netherlands.

The principle behind all these indexes is that dairy cows are not bred with only one or two traits in mind. Some breeders indicate that having breeding indexes makes breeding dairy cattle more complicated. However, from our exposure to breeders, The Bullvine hears that having total merit indexes assists breeders who want to breed for lifetime profit or to compare animals before buying semen or embryos.

Blindly following a total merit index is not a good practice. Breeders need to know the purpose for which a total merit index is designed. BW (New Zealand) is designed for year round grazing and low body mass. JPI (American Jersey) is designed with an emphasis on milk solids production.

Breeders need to have goals and a herd breeding plan to make maximum use of total merit indexes. Readers may wish to refer to previous Bullvine articles when establishing a herd breeding plan ( Read more: What’s the plan?, 4 Steps to Faster Genetic Improvement, 8 Steps to Choosing What Sires to Use).  Breeders need to look five years into the future to decide what will be the criteria they will judge their females by. It is entirely possible if a breeder plans to operate his dairy farm business differently in the future than they have in the past, it could be time to use a different total merit index than they have utilized in the past.

Have Genetic Indexes Been Useful?

Annually CDCB and CDN publish reports showing ever increasing rates of genetic advancement for NM$ and LPI, respectively. In fact, a recent CDN article states that half of the gain in Canada can be attributed to increased genetic merit.

In the barns around the world, individual breeders are seeing gains in their cows’ ability for production, type and now SCS. When a breeder makes extensive use of sexed semen, it can be expected that 80% of a herd’s improvement can be attributed to the sires that have been used. Definitely having total merit index rankings three times a year gives breeders the opportunity to find new top sires and to eliminate bulls that may be high for one or two individual traits but in total are not able to do a complete job. Since the introduction of TPI and LPI, one of the outcomes has been that high type sires, with inferior production ability, are used very infrequently on a population basis.

Current Reality in Genetic Indexes

With many total merit indexes and many many individual trait indexes routinely published, it can be both time consuming and confusing to keep up-to-date.

Yet the fact is that the number of indexes is increasing with every index run. For example, in the past year, there have been three new trait indexes for mastitis resistance, fertility and feed efficiency. In 2015 new added total merit indexes were Pro$ (CDN) and DWP$(TM) (Zoetis), the latter being an index produced by a private company (Read more: Can you breed a healthier cow?, The Complete Guide to Understanding Zoetis’ New Wellness Traits – CLARIFIDE® Plus, Will Genetic Evaluations Go Private?)

Tomorrow’s Indexes

Every year new indexes for important traits for varying herd management systems will continue to come into the world of dairy cattle breeding. The following questions may assist breeders in deciding upon which genetic indexes to consider:

  • Is the new index designed for the way you plan to practice dairy farming?
  • Why would you not take the opportunity to use new relevant information?
  • Who can give you the most objective view of new genetic indexes?

One size does not fit all.  Not every new genetic index, total merit or individual trait, will assist a breeder in breeding an ever more profitable herd.

The Bullvine Bottom Line

Are there too many indexes? Only if you don’t have a breeding plan, and you don’t make the right choice of a total merit index for your herd. It is not about the total number of genetic indexes. In the end, it’s about being selective and only using what’s best for you.

 

 

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Seven Key Players Form New EuroGenomics Cooperative

Eurogenomics[1]Seven key players have formed a co-operative aimed at exchanging genomic data in the Holstein breed as well as improving genomic evaluation techniques. The seven organizations are Viking Genetics from Scandinavia, Evolution and Origin Plus from France, CRV from the Netherlands, CONAFE from Spain and MCB Krasne and the Polish Federation of Cattle Breeders and Dairy Farmers. The newly formed co-operative EuroGenomic will use reference population that consists of over 33,000 genotyped bulls and will be looking for new ways to improve the effectiveness of  bovine breeding. The EuroGenoimcs Co-operative will also provide genomic test results on AI bulls over 10 months of age that are owned by third parties.

On-Farm Data: Challenges & Opportunities

There is no doubt that new technologies are changing our lives… seemingly every day! While this is true in our personal lives it is also true in the barn. In an effort to improve herd management and profitability by making timely, accurate decisions, technologies now exist for monitoring several important variables including the feed intake, body temperature, heat detection as well as lying, sleeping, movement and pre-calving behaviours of each cow in the herd. In addition to these, significant advances have been made in terms of technologies for measuring variables associated with milking, which can vary from daily milk weights from automated milking systems in parlours to more comprehensive data gathered from each cow and milking with robotic systems.

Milking Systems in Canada

Table 1 provides herd and cow statistics from across Canada by the type of milking system based on herds enrolled on DHI, which represents nearly 75% of all herds. Currently, over two-thirds of the herds in Canada, representing almost half of all cows, have a tie-stall environment.  Nearly 40% of all cows are milked in parlours even though these herds represent 22% of all herds.  In terms of the adoption of robotic milking systems as a new technology on the farm, a total of 567 herds on DHI (6.6%) currently have at least one robotic installation, representing over 60,000 and 8.7% of the cows on DHI.

Looking at Table 2 shows the regional variation in terms of the percentage of cows enrolled on DHI by milking system. Obvious differences include the percentage of cows in tie-stall herds in Quebec (76.5%), Ontario (47.6%), Atlantic Canada (28.6%) and Western Canada (6%), which is generally offset by the proportion in herds with a milking parlour.  Less regional variation exists in terms of cows milked with robotic systems, ranging from 10.6% in the West to 5.7% in Atlantic Canada.

On Farm Data

Considering the entire Canadian population on DHI,  nearly half of the cows are housed in a free stall environment, based on statistics for milking parlour and robotic systems combined. With advanced parlour setups and robotic milking systems comes sophisticated technology, and with sophisticated technology, comes an abundance of data. This is especially true in the case of the ever-growing segment of herds with robotic installations. After each milk recording test day, routinely collected data flows to the Canadian DHI centralized database and onward to CDN. However, “non-routine” data such as daily milk weights, in-line measurements of milk components, somatic cell count and/or progesterone, milk conductivity, milking times and flow rates, etc. are not currently being transferred.

Most producers with this additional data have the opinion that it has important value to the industry, especially for genetic improvement, and should be collected and used.  In some cases, this perspective becomes a source of producer frustration to a point where they question the value of participating in traditional programs such as registration, milk recording and/or conformation assessment. The reality, however, is that the accuracy and benefit of this additional data needs to be assessed and quantified.  While daily milk weights for each cow from robotic and other automated milking systems are likely quite accurate, it becomes critical that the cow identification information is also correctly aligned with the animal’s lifetime identification and registration number. More specific to assessing the value of on-farm technologies, the accuracy of in-line milk analysis of fat and protein components as well as somatic cell count needs to be validated.  Even if the overall herd results for average fat and protein percentages as well as average somatic cell score line up well with results based on the milk shipped, this does not confirm that results for each cow are accurate.  For such in-line results to be of benefit for genetic evaluation, in addition to herd management reports and benchmarking, the accuracy levels must be understood and validated. This type of validation research is an important topic here in Canada as well as several countries around the world.

Industry Initiatives

In early 2014, the Board of Directors of Canadian Dairy Network (CDN) appointed an ad-hoc committee to develop a plan to address the future needs of data collection in Canada. The final report, which was tabled in 2015, included recommendations associated with five specific strategies that were identified as important opportunities.  One of these strategies focused on the growing adoption of robotic and other automated milking systems on dairy farms across Canada. The primary need is the development and implementation of an internet-based interface for the routine transfer of authorized data for loading into a national centralized database. In 2015, Holstein Canada also initiated a project to assess the on-farm data that currently exists and the opportunities for collecting it as a means of improving the efficiency of core services provided by Holstein Canada and potentially other benefits to the industry and Canadian producers.

In summary, on-farm technologies are creating new opportunities for the collection of data for both herd management and genetic improvement.  Industry partners are in the process of assessing these opportunities, identifying which data has been validated to be of value, and considering technical solutions for efficiently retrieving data from on-farm systems in an automated manner and returning useful management information and/or genetic evaluations to producers. This will take some time and, as with many things, we need the best outcome not the fastest one!

Authors:
Brian Van Doormaal, General Manager, CDN
Lynsay Beavers, Industry Liaison Coordinator, CDN

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CDN is Improving Existing Traits and Adding Exciting New Ones

Some believe genomics is the be-all and end-all of the opportunity for genetic improvement. In reality, genomics is a by-product of solid traditional genetic evaluation systems and would not work without them as input. For this reason, Canadian Dairy Network (CDN) is continually improving both genomic AND traditional genetic evaluations to provide you with the most accurate overall genetic information possible for each animal. Read about some recent changes that have been made, as well as about some exciting things to come on the horizon.

Separating Somatic Cell and Production Traits

In 1999, Canada was one of the very first countries in the world to use each cow’s test day information for genetic evaluations instead of lactation-based data. Since that time the production traits, namely Milk, Fat and Protein yields, were evaluated simultaneously with Somatic Cell Score using statistical software called the “Canadian Test Day Model” (CTDM). While this system has served the industry very well for the past 15 years or so, research at CDN in recent years identified an opportunity to improve the stability of published Somatic Cell Score proofs.  Given the growing importance of this trait in the eyes of producers and its contribution towards both LPI and Pro$ indexes, CDN geneticists found that both production and Somatic Cell Score proofs would be improved, in terms of variability over time, if they were analyzed using two separate test day models rather than calculated simultaneously within a single multiple trait system.

Effective April 2016, the new approach of calculating production evaluations separately from Somatic Cell Score will be used for all breeds. This enhancement also required the calculation of new genetic parameters such as heritabilities and genetic correlations across traits. In addition to affecting Milk, Fat, Protein and Somatic Cell Score, the update can also lead to changes for Lactation Persistency and a minor impact on Herd Life, since Somatic Cell Score is a predictor of indirect Herd Life. For Holsteins, this improvement is expected to have no impact on LPI for 85% of proven sires and 76% of genotyped cows, and the most extreme changes will be a one-time adjustment of up to ±40 and ±130 LPI points for proven sires and cows respectively.

Daughter Fertility and Female Fertility Traits

Improvements to CDN’s traditional evaluations for female fertility are also expected before the end of this year, which mainly entails the use of pregnancy check data to better determine conception dates. The pregnancy check data collected from producers by DHI now provides CDN with the opportunity to improve the existing genetic evaluation system for traits related to female fertility, of which three reflect heifer fertility and four represent fertility in lactating cows.

The main traits to be affected by this improvement are the interval from first service/insemination to conception in both heifers and cows as well as days open. To date, subsequent calving records have been used to determine when conception occurred, simply by using the insemination record approximately 280 days prior to the calving date.  Utilizing data that confirms pregnancy status will reduce the time required to validate that conception actually did occur and it will also allow for the inclusion of conception dates for females that do not have a subsequent calving date at CDN. In terms of sire proofs for First Service to Conception, more data on daughters will be available, and about six months earlier, which therefore increases the accuracy of this trait, as well as Daughter Fertility as the overall index that combines key female fertility traits.

Novel Traits to Come in Canada

On-going research is set to release a wealth of new information in the coming years. Key areas of current research include health traits as well as feed efficiency and methane emissions.

  • Ketosis & Displaced Abomasum: Genetic evaluations for Clinical Mastitis and a Mastitis Resistance index were officially introduced in August 2014 as the first outcome of the National Health Project in 2006. The next fruit of this national system for producers to report on-farm health events are genetic evaluations for Ketosis, including BHB as an indicator of sub-clinical ketosis, and Displaced Abomasum, which will all be combined into a Metabolic Disease Resistance index. The target date for official implementation of this new genetic evaluation system is December 2016.
  • Metritis & Retained Placenta: Stemming from the same source of on-farm data collection of health events mentioned above, genetic evaluations are under development for resistance to fertility disorders, including Metritis and Retained Placenta. Expect to see new proof information available in 2017.
  • Hoof Health/Lameness: Hoof health data acquired from Hoof Supervisor software, used by a growing number of Canadian hoof trimmers, has undergone research and proven to be an area of opportunity for genetic selection. The recording of various infectious and non-infectious lesions as well as other hoof health characteristics, observed at the time of hoof trimming, serves as an excellent source for building a national system for herd management and genetic evaluation with the aim of reducing costs of treatment and lameness. The ongoing research project has established a data collection system to allow routine data transfer from Hoof Supervisor to DHI and on to CDN. An important outcome of this project will be the implementation of genetic and genomic evaluations for hoof health traits with targeted implementation by 2018.
  • Feed Efficiency and Methane Emissions: CDN has taken the leadership role in conducting a major research initiative, involving international partners, that targets the use of genetics and genomics for improving feed efficiency and reducing methane emissions in dairy cattle.  The project received $3.8M in funding from Genome Canada and will involve the collection of individual cow feed intake data and genotypes from two research herds and two producer-owned partner herds in Canada.  The ultimate goal is the implementation of new genetic and genomic evaluation systems for these traits in the coming years.

As is the case in all industries, the only thing constant is change – the same goes for Canadian genetic evaluations. Improvements to methodology, incorporating new data to strengthen existing evaluations, and the development  of novel traits all contribute to maintaining Canada’s status as a world leader in dairy cattle improvement.

By: Lynsay Beavers, Industry Liasion Coordinator, CDN & Brian Van Doormaal, General Manager, CDN

Améliorer les caractères existants et en ajouter de nouveaux passionnants

Certains croient que la génomique est l’alpha et l’oméga des possibilités d’amélioration génétique. En réalité, la génomique est un sous-produit de systèmes d’évaluation génétique traditionnels solides et ne pourrait pas fonctionner sans leur contribution. Pour cette raison, le Réseau laitier canadien (CDN) améliore continuellement à la fois les évaluations génomiques ET les évaluations génétiques traditionnelles pour vous offrir l’information génétique globale la plus précise possible pour chaque animal. Découvrez les changements qui ont été effectués ainsi que les choses passionnantes qui se pointent à l’horizon.

Séparer les cellules somatiques et les caractères de production

En 1999, le Canada a été un des tout premiers pays au monde à utiliser l’information du jour du contrôle de chaque vache pour les évaluations génétiques au lieu des données basées sur la lactation. Depuis ce temps, les caractères de production, notamment les rendements en lait, en gras et en protéine, ont été évalués simultanément au moyen de la cote de cellules somatiques utilisant un logiciel statistique appelé le « Modèle jour du test canadien» (MJTC). Bien que ce système ait très bien servi l’industrie pendant une quinzaine d’années, la recherche effectuée à CDN au cours des dernières années a permis d’identifier une possibilité d’améliorer la stabilité des épreuves publiées pour la Cote de cellules somatiques. Compte tenu de l’importance croissante de ce caractère aux yeux des producteurs et de sa contribution aux indices d’IPV et Pro$, les généticiens de CDN ont constaté qu’à la fois les épreuves en production et la Cote de cellules somatiques seraient améliorées, en matière de variabilité au fil du temps, si elles étaient analysées au moyen de deux modèles du jour du test séparés au lieu d’être calculées simultanément à l’intérieur d’un seul système à caractères multiples.

À partir d’avril 2016, la nouvelle approche visant à calculer séparément les évaluations de la production et de la Cote de cellules somatiques sera utilisée dans toutes les races. Cette amélioration a aussi exigé le calcul de nouveaux paramètres génétiques comme les héritabilités et les corrélations génétiques entre les caractères. En plus d’affecter le Lait, le Gras, la Protéine et la Cote de cellules somatiques, la mise à jour peut aussi entraîner des changements dans la Persistance de lactation et avoir un impact mineur sur la Durée de vie, puisque la Cote de cellules somatiques est un prédicteur de la Durée de vie indirecte. Chez les Holstein, il est prévu que cette amélioration n’aura pas d’impact sur l’IPV de 85 % des taureaux éprouvés et de 76 % des vaches génotypées, et les changements les plus extrêmes seront un rajustement unique pouvant aller respectivement jusqu’à ±40 et ±130 points d’IPV pour les taureaux éprouvés et les vaches.

Caractères de Fertilité des filles et de Fertilité femelle

Des améliorations aux évaluations traditionnelles de CDN pour la fertilité femelle sont aussi prévues d’ici la fin de l’année, ce qui entraîne principalement l’utilisation de données de vérification de la gestation pour mieux déterminer les dates de conception. Les données de vérification de la gestation que le contrôle laitier recueille auprès des producteurs donnent maintenant à CDN l’occasion d’améliorer le système d’évaluation génétique existant pour les caractères liés à la fertilité femelle, dont trois reflètent la fertilité des génisses et quatre représentent la fertilité chez les vaches en lactation.

Les principaux caractères qui seront affectés par cette amélioration sont l’intervalle entre la première insémination et la conception à la fois chez les génisses et les vaches, ainsi que les jours ouverts. Jusqu’à maintenant, des relevés de vêlages subséquents ont été utilisés pour déterminer le moment de la conception, simplement en utilisant le relevé d’insémination environ 280 jours avant la date de vêlage. L’utilisation de données qui confirment le statut de la gestation réduira le temps requis pour valider que la conception a effectivement eu lieu et permettra aussi l’inclusion des dates de conception pour les femelles qui n’ont pas une date de vêlage subséquent à CDN. En ce qui concerne les épreuves des taureaux pour la Première insémination jusqu’à la conception, un plus grand nombre de données sur les filles seront disponibles environ six mois plus tôt, ce qui augmente donc la précision de ce caractère, ainsi que la Fertilité des filles, en tant qu’indice global qui combine les principaux caractères de fertilité femelle.

Nouveaux caractères à venir au Canada

Les recherches en cours devraient fournir une mine de nouveaux renseignements au cours des prochaines années. Les domaines clés de la recherche actuelle incluent les caractères de santé ainsi que l’efficience alimentaire et les émissions de méthane.

  • Cétose et déplacement de caillette : Les évaluations génétiques de la Mammite clinique et de la Résistance à la mammite ont été officiellement introduites en août 2014 en tant que premier résultat du Projet national de santé en 2006. Le prochain fruit de ce système national par lequel les producteurs signalent les problèmes de santé à la ferme est l’évaluation génétique de la cétose, incluant le BHB comme un indicateur de la cétose sous-clinique, et du déplacement de la caillette, qui seront tous combinés en un indice de Résistance aux maladies métaboliques. La date ciblée pour la mise en œuvre officielle de ce nouveau système d’évaluation génétique est décembre 2016.
  • Métrite et rétention du placenta : Issues de la même source de collecte de données à la ferme pour les problèmes de santé mentionnés ci-dessus, des évaluations génétiques sont en cours de développement pour la résistance aux troubles de fertilité, incluant la métrite et la rétention du placenta. Attendez-vous à ce que de nouveaux renseignements sur les épreuves soient disponibles en 2017.
  • Santé des sabots/boiterie : Des données sur la santé des sabots recueillies par le logiciel Hoof Supervisor, utilisé par un nombre croissant de pareurs canadiens, ont fait l’objet de recherche et se sont avérées comme étant une occasion de sélection génétique. La consignation de différentes lésions infectieuses et non infectieuses ainsi que d’autres caractéristiques sur la santé des sabots, observées au moment du parage, sert d’excellente source pour bâtir un système national de gestion de troupeau et d’évaluation génétique dans le but de réduire les coûts du traitement et de la boiterie. Le projet de recherche en cours a permis de mettre sur pied un système de collecte de données permettant un transfert régulier de données de Hoof Supervisor au contrôle laitier, puis à CDN. Un important résultat de ce projet sera des évaluations génétiques et génomiques des caractères de santé des sabots avec une mise en œuvre ciblée d’ici 2018.
  • Efficience alimentaire et émissions de méthane : CDN a assumé le rôle de chef de file en dirigeant une importante initiative de recherche, à laquelle ont participé des partenaires internationaux, qui cible l’utilisation de la génétique et de la génomique pour améliorer l’efficience alimentaire et réduire les émissions de méthane chez les bovins laitiers. Le projet a fait l’objet d’un financement de 3,8 M$ de Génome Canada et consistera en la collecte de données individuelles sur la prise alimentaire et les génotypes des vaches dans deux troupeaux de recherche et deux troupeaux partenaires appartenant à des producteurs au Canada. Le but ultime est de mettre en œuvre de nouveaux systèmes d’évaluation génétique et génomique de ces caractères dans les années à venir.

Comme c’est le cas dans toutes les industries, la seule chose qui ne change pas est le changement – et cela s’applique aussi aux évaluations génétiques canadiennes. Des améliorations à la méthodologie, en incorporant de nouvelles données pour renforcer les évaluations génétiques et le développement de nouveaux caractères contribuent tous au maintien du statut du Canada comme chef de file mondial dans l’amélioration des bovins laitiers.

Auteurs :
Lynsay Beavers, coordonnatrice de la liaison avec l’industrie, CDN
Brian Van Doormaal, directeur général, CDN

Source: Canadian Dairy Network

GENETICS vs. ENVIRONMENT: Do Genetics Perform Uniformly in All Environments?

In current genetic evaluations, we lump data together, nationally and internationally. It is combined into one data set where we carry out the various analyzes to arrive at genetic indexes for all animals. But is that combining correct? Are there, in fact, any genetics by environment interactions situations that need consideration when combining data?  Should genetic evaluations be run separately for grazing herds compared to barn fed and housed herds?

What Does Cow Sense Tell Us?

Cow people know that there are some sire daughter groups and some cow families that perform differently when placed in different environments.

How often have you heard knowledgeable cow persons say – “He sires good useful barn cows but not enough show ring worthy daughters to have a PTAT of 3.21.” Or. “That cow family is great provided you go to the effort of pampering them like babies.”

Some Examples Where Proofs Have Not Always Told the Story

I have seen situations where sires’ daughters do not uniformly perform according to their indexes across all environments.

Quality Ultimate sired strength and stature as well as average milk and good fat percent, but he got the knock for not being tie stall friendly and lacking in daughter mobility in Canada, where he was proven. Yet in Australia breeders have told me that his mobility was not a problem. Why? Well, in Canada in tie stall barns with little to no access to exercise for 60% of the year, Ultimate daughters did not get the exercise they needed and so his proof was accurate, he had a feet and legs limitation. But, in Australia where cattle are outside walking on the ground all year, his daughter’s feet and legs were not a problem. (Read more: Mobility – The Achilles Heel of Every Breeding Program)

Looking beyond Ultimate, each of us can think of other bulls that may not suit all breeders’ needs. I think of Roybrook Starlite whose daughters were high yielders, but they often needed some special care and close monitoring. That is not something most commercial milk producers were prepared to do. Starlite’s maternal line had been a line bred family from a herd that took superb care of their animals.

Love Them or Hate Them

Today breeders either love or hate show bull Goldwyn and the commercial breeder’s dream bull, Oman. (Read more: Why Braedale Goldwyn Wasn’t a Great Sire of Sons)

A bull’s proof is an estimate of his average daughter. In extreme situations or environments, a bull’s proof may not be an accurate prediction of his true worth. How can breeders know if a bull will work, as his proof predicts, on their farm? Very little gets a breeder more upset that having a bull not perform in accordance with his proof.

Goldwyn in large commercially run groups of cows and Oman in the show ring are not good fits for what their proofs said should have ben expected.

Cow Indexes Open To More Environmental Influence

Of course, when it comes to cow indexes there are numerous examples of cows and cow families where the indexes are not accurate in predicting how they will breed on. (Read more: Has Genomics Knocked Out Hot House Herds?)

Now with genomic information included in genetic evaluations, the accuracies of prediction for cow indexes have been doubled and, therefore, may not be quite as variable in accuracy as they were in the past. Discerning breeders know that some cow families work best in certain single environments.

Points To Ponder

When conducting genetic evaluations, assumptions are made. Most of these assumptions have been shown to enhance the resulting genetic indexes. However here are a few assumptions that may contribute to inaccuracies when the indexes are used across all dairy farming situations.

  • Including Only Partial Herd Data
    Not including all contemporaries in type classification or herd recording data, when conducting BLUP genetic evaluations, violates the BLUP assumption that all animals are handled in a similar manner within a herd. Applying the results from selected data can lead to breeders questioning the daughters they get from a sire or cow family based on their genetic indexes.
  • Combining International Data Sets
    Definition of traits, variances within the data and methods of farm operation are different country to country. Interbull includes data from many production environments from many countries when doing its index calculations. Breeders should carefully interpret the results of combined international indexes when applying them back to their own herd environment.
  • Multiple Breeding Programs Within A Herd
    BLUP genetic evaluations assumes that only one breed program, one feeding program, and one management system exists in a single herd. If that assumption is violated then genetic evaluation results, especially cow indexes, can be less accurate than reported.
  • Sires Proven on Early Release Semen
    Most breeding companies release their high genomic young sires to themselves or selected herds six to nine months before it is made available to all breeders. It is imperative that the genetic evaluation procedures used for evaluating early release sires accurately adjusts for the genetic merit of the sire’s mates and the herds where the daughters are found.
  • Cows and Technology
    With many new technologies coming to market, breeders can expect to see genetic indexes for how cows adapt or perform within a technology. One such area is how cows work in single robotic milking farms. For example, breeders need to understand what is included when a bull’s daughters are called robot ready. Is that simply rear teat placement or does it include other factors as well (i.e. udder depth, milk let down, milking temperament, etc.)?
  • Genomic Information Not Yet Universal
    Even though the global dairy cattle breeding industry is almost into the ninth year of using genomic information, the genomic information and method of including the genomic results in genetic evaluations are not universal country to country. Breeders using genomic indexes from other countries need to do their homework before buying semen or embryos from abroad.

Does This Topic Need Attention?

The short answer is YES. To constructively improve their dairy cattle, breeders need to trust the numbers they use when making breeding decisions. Differences, biases, and inaccuracies in the data must be accounted for when conducting genetic evaluations.  As milk products become more of the global diet and as dairy cow populations expand, especially into more tropical conditions, breeders will need to know which cow families and sire daughter groups will work best in which environments.

The Bullvine Bottom Line

The genetic evaluations of tomorrow need to make sure that biases and inaccuracies are not created but rather eliminated when data sets are combined. The saying “Horses For Courses” comes to mind when considering bloodlines that will work better in one environment than another.

 

 

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The Complete Guide to Understanding Zoetis’ New Wellness Traits – CLARIFIDE® Plus

For the first time, dairy producers can genetically select heifers to build a healthier herd.  But with this new ability comes the challenge of understanding Zoetis’ New Wellness Traits marketed at CLARIFIDE® Plus (Read more:  ZOETIS LAUNCHES CLARIFIDE® PLUS and Can you breed a healthier cow?).  In order to help you understand the power of this new tool here are some useful resources to guide you in your understanding.

Key Points

  • CLARIFIDE® Plus represents the first commercially available dairy genetic evaluation specifically designed for wellness traits in U.S. dairy cattle.
  • CLARIFIDE Plus genomic predictions for wellness traits provide reliable assessments of genetic risk factors for economically relevant health challenges in Holstein cattle.
  • The use of Dairy Wellness Profit Index (DWP$) would be expected to offer very similar selection emphasis to that achieved by Net Merit (NM$), making it a practical consideration for producers that have historically used NM$, but would like to apply additional selection emphasis on wellness traits.
  • CLARIFIDE Plus provides an expanded suite of genetic selection tools that provide highly relevant information to dairy producers who seek to incrementally improve the health, productivity and profitability of the dairy cattle they care for.

Genetic evaluation and selection in dairy cattle has largely focused on production traits such as milk and protein production. Indirect predictors of health and fertility (e.g.,somatic cell score, productive life, daughter pregnancy rate) are available and there is evidence to support some genetic improvement for these traits. However, presumably as a result of genetic antagonisms between production and health traits as well as changes in management practices, data supports increased incidence of many common diseases in contemporary dairy production systems. Consequently, dairy cows are considered to be less ‘robust’ than previous generations, which has serious implications for the health and fertility of the modern day dairy cow.

Profitable dairy cows are fertile, productive and require minimal extraneous inputs to maintain their health through all phases of production. They generally require fewer veterinary treatments or interventions, without compromising the health, welfare or economic efficiency of the cow, and are less likely to be prematurely culled. Genetic improvement programs that incorporate knowledge regarding differences in risk of disease into selection and breeding strategies have the potential to improve profitability of dairy production through improved prevention and control of economically relevant diseases as well as enhanced animal productivity.

Improving health and fitness traits, commonly referred to as functional or wellness traits, through genetic selection presents a compelling opportunity for dairy producers to help manage disease incidence and improve profitability when coupled with sound management practices. To date, direct predictors for wellness traits related to common disease conditions in dairy production have not been readily available in the U.S. CLARIFIDE® Plus represents the first commercially available dairy genetic evaluation specifically designed for wellness traits in U.S. dairy cattle, providing predictions describing the risk for six common diseases. Routine dehorning of commercial dairy cattle is also of concern for the industry as it relates to animal well-being and costs associated with routine dehorning methods. The selection and breeding of polled stock has been proposed as a strategy for proactively managing these concerns, including use of direct tests for polledness in cattle as well as including the economic benefits within selection indexes. CLARIFIED Plus includes the Zoetis Polled genomic test prediction in the offering to accurately identify and differentiate homozygous vs. heterozygous polled Holstein animals.

clarifideplus_1200x834[1]

Overview

  • Mastitis, lameness, metritis, retained placenta, ketosis, displaced abomasum and other health events referred to as wellness traits have a significant impact on herd health, saleable milk and overall herd profitability.
  • Profitability is enhanced when the dairy has the advantage of mature cows that are productive for multiple lactations. To reach this longevity, cows must stay healthy and be reproductively sound, in addition to producing milk. Until now, management practices were the primary way to help cows either avoid or survive these health events.
  • CLARIFIDE Plus represents the first commercially available dairy genetic evaluation specifically designed for wellness traits in U.S. dairy cattle. Dairy producers can now genomically select heifers for wellness traits at an early age to help build a healthier herd.
  • CLARIFIDE Plus is the only genomic test that allows producers to rank animals with the new Dairy Wellness Profit IndexTM (DWP$TM) based on traits that affect health, performance and profit.
  • The use of Dairy Wellness Profit Index (DWP$) would be expected to offer similar selection emphasis to that achieved by Net Merit (NM$), making it a practical consideration for producers that have historically used NM$, but would apply additional selection emphasis on wellness traits.
  • CLARIFIDE Plus derives accurate genetic predictions for six new wellness traits derived using cutting‐ edge genetic evaluation methodology applied to data collected from millions of health records within U.S. commercial herds. This results in an average Reliability of 50% for the six traits.
  • Higher values are more desirable for all traits, thus selecting for a high Standardized Transmitting Abilities (STA) will apply selection pressure for reduced risk of disease.
  • In addition to wellness traits, CLARIFIDE Plus includes genetic information for the Zoetis propriety Polled trait.
  • DWP$ includes production, fertility, type, longevity and the dairy wellness traits, including polled test results.
  • Wellness Trait IndexTM (WT$TM) focuses on the wellness traits (Mastitis, Lameness, Metritis, Retained Placenta, Displaced Abomasum and Ketosis) in addition to Polled and estimates difference in expected lifetime profit associated with risk of disease.
  • DWP$ differs from other economic indexes because it includes direct predictions for economically important diseases. By including more characteristics affecting profitability, DWP$ describes more variation in profitability than other indexes.
  • With the use of DWP$, producers can potentially make more than $55 more profit per selected female over 10 years using a 15% culling selection strategy, even when test cost is higher than a NM$‐based ranking.

Development of Dairy Wellness Predictions

Genomic predictions for wellness traits were developed by Zoetis based on an independent database of pedigrees, genotypes and production records assembled from commercial dairies and internal assets. Health events were assembled from on-farm dairy production records provided with consent by commercial dairy producers. Data editing procedures to reduce recorded disease incidence to a common format were developed based on review of event codes in on-farm software and consultation with dairy production and veterinary experts. Targeted phenotypes included:

  • Mastitis (MAST)
  • Lameness (LAME)
  • Metritis (METR)
  • Retained placenta (RP)
  • Displaced abomasum (DA)
  • Ketosis (KET)
 All diseases were defined as a Holstein female diagnosed with the respective disease one or more times in a given lactation on the basis of qualifying event codes in on-farm dairy software in the case of commercial data, or clinical research records in the case of internal research assets. As of August 2015, the database used to derive CLARIFIED Plus predictions incorporated, primarily large commercial U.S. dairy operations from across the nation and included more than 10 million lactation records; 4 million cases of mastitis; 3 million cases each of metritis, retained fetal membranes, displaced abomasum, and lameness; more than 1.9 million cases of ketosis; and more than 15 million pedigree records. Additional records are continuously added to this database on a monthly basis from producer-supplied farm records.

Genomic data was obtained from commercially tested animals with owner consent or available genotypes within Zoetis research databases. More than 100,000 genotypes were available for consideration as of August 2015. Additional commercial genotypes are added on a weekly basis. Genotypes included in the evaluation were derived from both low and medium density genotypes, all imputed to Illumina®  BovineSNP50v2 using an internal imputation reference set and FImpute.CLARIFIDE Plus predictions are derived from a weekly internal genetic evaluation that employs single-step statistical methods for estimating genomic breeding values. This method for genetic evaluation derives a joint relationship matrix based on pedigree and genomic relationships and provides a unified framework that eliminates several assumptions and parameters, thus enabling more accurate genomic evaluations. Table 1 shows the average reliability of genomic predictions for wellness traits in CLARIFIDE Plus. Among approximately 29,901 Holstein heifers less than 2 years of age within the reference dataset, the average reliability was greater than or equal to 49% for all traits. Notably, as direct predictions for individual wellness traits are not presently available, this represents a substantial increase in reliability from zero. Further, the average reliability of genomic predictions for wellness traits continues to increase as more records are added to the evaluation.

Table 1 - clarifiedplus

Reporting of Wellness Traits in CLARIFIDE® Plus

CLARIFIDE® Plus predictions for wellness traits are expressed as genomic standardized transmitting abilities (STA), similar to how type traits are expressed. Values are centered at 100 with a standard deviation of 5. The reference population included 76,840 animals that had wellness predictions and CLARIFIDE results (Table 2). For all wellness trait predictions, a value of 100 represents average expected disease risk and values of greater than 100 reflect animals with lower expected average disease risk relative to herdmates with lower STA values. Higher values are more desirable for all traits, thus selecting for a high STA will apply selection pressure for reduced risk of disease.

Table 2 - clarifiedplus

CLARIFIDE Plus predictions for the Polled test will be reported as:

  • Tested homozygous polled: The genotype demonstrates that the animal is homozygous polled and will always produce a polled animal regardless of the horned status of the other parent.(Coded PP)
  • Polled carrier: The genotype reveals a heterozygous polled animal capable of producing a horned progeny. (Coded PC)
  • Tested free of polled (i.e., horned): The genotype is consistent with an animal that is horned. (Coded TP)
  • Indeterminate: The polled status of the animal cannot be definitively determined. (Coded I)

Two New Dairy Wellness Indexes

In addition to reporting of individual wellness traits, CLARIFIDE Plus also reports two economic selection indexes to inform selection decisions. Selection indexes are a critical component of many selection strategies as they provide a path for dairy producers to select for comprehensive genetic improvement across many economically important traits. The use of economic selection indexes helps to ensure that the distribution of selection pressure applied to component traits is appropriately balanced relative to the economic impact of the individual traits on dairy profitability. To support selection for reduced risk of disease in dairy females, two economic indexes were developed.

  • Wellness Trait Index (WT$): This multi-trait selection index exclusively focuses solely on the wellness traits1 (Mastitis,Lameness, Metritis, Retained Placenta, Displaced Abomasum, Ketosis and Polled) and directly estimates potential profit contribution of the wellness trait for an individual animal that will be passed onto the next generation.
  • Dairy Wellness Profit Index (DWP$): This multi-trait selection index includes production, fertility, type, longevity, calving ability, milk quality and the wellness traits, including Polled test results. By combining the wellness traits with those found in the current Net Merit (NM$) index, DWP$ directly estimates the potential profit contribution an individual animal will pass along to the next generation.

Table 3 - clarifiedplus copyThe economic indexes in CLARIFIDE Plus were derived using standard selection index theory. Economic assumptions were derived from those used in NM$ for the case of core traits, and from a review of peer-reviewed literature for wellness traits. Economic values for health traits that are considered in the derivation of NM$ were removed to avoid double-counting of the contributions of disease to dairy profitability. Economic values were then adjusted within the range of reported values based on the covariance among traits to achieve the final index weights.
To assess the extent to which use of CLARIFIDE Plus wellness trait indexes would alter selection emphasis relative to use of NM$, the expected response to selection per standard deviation of genetic improvement in the index was estimated. In examining the response of selection between DWP$ and NM$, it is clear that use of DWP$ will result  in greater genetic improvement in wellness traits and largely the same selection response for the rest of the traits. There is some decrease in selectionemphasis and expected genetic progress for production traits associated with the use of DWP$ (Table 3), which is consistent with our understanding of the relationship between increased production and disease risk. However, selection using DWP$ will increase milk, fat and protein production, just at a slightly lower genetic rate than would be achieved with alternative indexes that do not consider direct selection for wellness traits. Importantly, the use of DWP$ would be expected to offer very similar selection emphasis to that achieved by NM$, making it a practical consideration for producers who have historically used NM$ but would like to apply additional selection emphasis on wellness traits to achieve healthier, more profitable cows.

Table 4 defines the relative values for component traits in each of the two  wellness indexes. All indexes are expressed in a dollar value with higher positive numbers indicating the animal has the genetic potential to generate and transmit more profit over her lifetime.

Table 4 - clarifiedplus

CLARIFIDE® Plus Educational Videos 

  •  Improving Dairy Health and Profitability With CLARIFIDE® Plus in Holsteins
    CLARIFIDE Plus represents the first commercially available dairy genetic evaluation specifically designed for wellness traits in U.S. dairy cattle. Dairy producers now can genomically select heifers for wellness traits at an early age to build a healthier herd. Cheryl Marti, associate director of genetics and reproduction with Zoetis, provides an overview of the technology and how it benefits Holstein dairy producers.
  • Creating Wellness Trait Genomic Predictions
    Dr. Sue DeNise, executive director of VMRD genetics with Zoetis, describes the process and research that went into product development for the wellness traits associated with CLARIFIDE Plus.
  • Understanding How CLARIFIDE Plus Wellness Traits Are Reported
    Dr. Dan Weigel, director of Outcomes Research at Zoetis, describes the wellness traits associated with CLARIFIDE Plus and how the genetic results for each wellness trait are reported.
  • Exploring CLARIFIDE Plus Wellness Traits: Mastitis
    Mastitis is one of the most costly diseases on U.S. dairy herds. Dr. Gary Neubauer, senior manager of Dairy Technical Services, and Dr. Dan Weigel, director of Outcomes Research, discuss the genetic components of mastitis and how the wellness trait is reflected within CLARIFIDE Plus.
  • Exploring CLARIFIDE Plus Wellness Traits: Lameness
    Lameness is a widespread disorder among the U.S. dairy cattle population and has a significant impact on health and productivity. Two Zoetis technical services personnel — Dr. Gary Neubauer, senior manager of Dairy Technical Services, and David Erf, a Dairy Technical Services geneticist — provide an overview of the genetic component of the lameness wellness trait.
  • Exploring CLARIFIDE Plus Wellness Traits: Metritis and Retained Placenta
    Metritis and retained placenta are two significant disorders that impact fresh cows. Two Zoetis technical service personnel — Dr. Michael Lormore, director of Cattle and Equine Technical Services – Dairy, and Dr. Anthony McNeel, senior scientist with Global Genetics Technical Services — discuss the genetic components of these traits and how they are reflected within CLARIFIDE Plus outcomes.
  • Exploring CLARIFIDE® Plus Wellness Traits: Ketosis and Displaced Abomasum
    Two Zoetis technical service personnel — Dr. Michael Lormore, director of Cattle and Equine Technical Services – Dairy, and David Erf, a Dairy Technical Services geneticist — explore two traits included within the CLARIFIDE Plus offering: ketosis and displaced abomasum. The presentation details the significance of the two disorders and the genetic components of each trait.
  • The CLARIFIDE Plus Wellness Trait Index™ (WT$™)
    Brenda Reiter, a Global Genetics Technical Services scientist with Zoetis, provides an overview of the Wellness Trait Index (WT$). The index is a multitrait selection index that focuses specifically on genomic predictions for common health disorders of dairy cattle.
  • The Power of the Dairy Wellness Profit Index™ (DWP$™)
    CLARIFIDE Plus is the only genomic test that allows producers to rank animals with the Dairy Wellness Profit Index (DWP$) based on important traits that affect health, performance and profit. Dr. Jason Osterstock, director of Global Genetics Strategic Marketing with Zoetis, describes how DWP$ was developed and how dairy producers can use DWP$ to make more informed heifer selection decisions.
  • Strategies for Using the Dairy Wellness Profit Index™ (DWP$™)
    David Erf, a Dairy Technical Services geneticist with Zoetis, provides an overview of how to use the Dairy Wellness Profit Index (DWP$). The presentation outlines strategies dairy producers can use to implement DWP$ data to sort, select and mate Holstein dairy heifers.
  • Achieving Faster Genetic Progress with DWP$
    In traditional breeding programs without genomics, it can be challenging to make significant progress within traits that have low heritability. Dr. Dan Weigel, director of Outcomes Research at Zoetis, describes how faster genetic progress can be made through genomic technology by using direct selection of the new wellness traits and using DWP$ within CLARIFIDE Plus.
  • Achieving Dairy Wellness Outcomes with CLARIFIDE Plus
    Cheryl Marti, associate director of genetics and reproduction with Zoetis, provides an overview of the Zoetis Dairy Wellness outcomes approach and how CLARIFIDE Plus supports this process for healthy animals and healthy dairies

Frequently Asked Questions

Q: What health events will be covered by wellness trait predictions?
A: Common diseases in dairy cattle including mastitis, lameness, metritis, retained placenta, displaced abomasum and ketosis will be part of the wellness trait offering.

Q: Why do I need DWP$?
A: There are several reasons to utilize DWP$ in an effective genetic management strategy:
* DWP$ provides comprehensive, accurate and specific information on wellness traits to provide clarity and opportunity to make more profitable animal rankings and decisions.
* By including more characteristics affecting profitability, DWP$ describes more variation in profitability than other indexes.
* The use of DWP$ would be expected to offer very similar selection emphasis for production, reproduction and type traits as NM$ but with additional selection emphasis on wellness traits.

Q: As a dairy producer, if I select cattle based on their wellness trait profile, does that mean that they won’t get mastitis, metritis, etc.?
A: Risk of disease is influenced by genetic and environmental factors. CLARIFIDE Plus describes differences in the genetic risk factors, but genetic selection will not compensate for suboptimal management practices that may cause animals with apparent lower risk of disease to get sick. Producers should continue to use best management practices to prevent disease and apply CLARIFIDE Plus as another tool to improve dairy wellness.

Q: How long before I see a benefit to using these wellness traits?
A: The rate of Genetic progress depends on 4 factors—selection intensity, genetic variation, heritability and generation interval. Herds can make faster genetic progress by using DWP$ through greater selection pressure and higher genetic variation compared to NM$.

Q: How can I justify the investment in CLARIFIDE Plus?
A: The combination of wellness trait information and economic implications delivered through DWP$ provide dairy producers with powerful information that can be used to help build a healthier, more productive herd. With DWP$, producers get a more comprehensive ranking because of the additional differences in profitability described by including direct predictions for economically important health events such as mastitis, lameness, metritis, etc. By including more characteristics affecting profitability, DWP$ (offered only in CLARIFIDE Plus) describes more genetic variation in profitability than other indexes.

Q: How can I order the wellness trait predictions or find additional information?
A: Currently, CLARIFIDE Plus is only available for use in Holstein cattle. Holstein producers can order the CLARIFIDE Plus test through the order form at www.clarifide.com or via Enlight® www.enlightdairy.com . For more information, contact Zoetis Customer Service at 877‐233‐3362 or your Zoetis representative.

THE BULLVINE BOTTOM LINE

Dairy producers have enjoyed the availability of a comprehensive list of economically relevant traits and a robust genetic evaluation system to fuel their genetic improvement strategies. To date, a gap has existed in the ability to improve dairy profitability and dairy cow well-being through direct genetic selection for susceptibility to common diseases. CLARIFIDE® Plus provides accurate genetic predictions for wellness traits derived using cutting-edge genetic evaluation methodology applied to data collected from commercial production settings. The result is an expanded suite of genetic selection tools that provides highly relevant information to dairy producers that seek to continue to improve the health, productivity and profitability of the dairy cattle they care for.

Want to learn more?  Check out our upcoming webinar  “New Innovation in Genomic Selection to Reduce Disease Risks” presented with Zoetis on March 16th  & March 23rd

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Will Genetic Evaluations Go Private?

Dairy cattle breeders have come to rely on their genetic indexes being calculated on a national or international basis by governments or independent industry organizations. Here at The Bullvine, we often refer to CDCB, CDN, VIT, ADHIS, Breed Societies and Interbull without mentioning their credentials or neutrality because we have trust in the numbers they produce for breeders to use to genetically advance their cattle. CDCB (Council on Dairy Cattle Breeding) in the USA is the newest of these organizations, and it has grown out of the AIPL-USDA’s decision to discontinue the production trait genetic indexing service for the US dairy cattle industry.

However, on the horizon is a considerable amount of on-farm data that national evaluation centers are not using. As well there is the desire by (A.I.) breeding companies to have and use genetic indexes for traits for which there is data but which may be outside the data standards that the national centres require or for which the companies do not wish to pay the fees charged by national centers. Add to that, new national trait evaluations are very slow in their development and approval.

So The Bullvine asks “Will genetic evaluations go private?”.

Private Is Not New

Privately produced trait rating systems have been around since the early days of A.I.  Breeders wanted to know facts, so A.I. organizations produced ratings starting with sire semen fertility followed by numerous other characteristics of their bulls’ daughters. One difficulty with these organization based systems was that each had its unique method of expression. This meant that breeders had to understand and remember many rating systems. It did, however, allow A.I.’s to have something unique in their tool box.

Another alternative, though perhaps not entirely private, is the improvement industry in New Zealand where LIC captures the data, calculates the genetic indexes, samples the bulls and markets the bulls. Arms length decision making and lack of diversity in the breeding program are questioned by breeders who use NZ genetics.

Data Standards

To do national and international genetic evaluations, where large volumes of data are included, it is paramount that the data combined have commonalities in such things as number of days milked, milking frequency, lactation number and age at classification. With the requirement for standardization, it results in the process of developing new genetic indexes being a relatively long process. That does not work well in a time of rapidly changing breeder needs for additional traits or when breeding companies have unique marketing plans.

Standardization adds cost. It is only worth it if the benefits for the population exceed the costs.

What Data Is Not Standardized?

Today there is a rapidly growing volume of data uniquely collected by companies. In the past half decade, the increase in the number of automated data capture devices has been dramatic. Rumination rate, animal activity, milking frequency, milk per quarter, milk temperature, hormone levels…it is almost an endless list. (Read more: BETTER DECISION MAKING BY USING TECHNOLOGY) And the list only gets longer every month. An important note is that each company and device has its method of data capture and expressing the results.

Another factor that breeders find confusing is that, although similarly named, traits are different in the ways that they are calculated and reported. Some of these traits include feed efficiency, fertility, length of herd life, ability to transition from dry to milking and mobility. It all depends on the organization, national genetic evaluation centre, breed society, A.I. or service company, doing the evaluation.

What Additional Indexes Could There Be?

Here again, the list of genetic indexes that could be possible is endless. A few that the Bullvine has heard breeders considering or organizations planning to produce include:

  • Milk let down and minutes to milk
  • Ability of animals to adapt to equipment and systems
  • Cow rejection rate in single unit robotic systems or cow visitation rate
  • Animal fertility including ability to conceive, early embryonic death and abortion rate
  • Animal behavior and social interaction
  • Feed intake and feed conversion
  • Animal mobility
  • Calf growth, health, feed conversion, disease resistance, .., etc.
  • Embryo production during embryo transfer
  • Ability to produce show winning progeny

Yes, the genetically related list is long. And beyond genetic indexes breeders will want many management and business related details. I received a novel question a month ago when a breeder ask if it could be possible for him to separate A1A1 and A1A2 milk from A2A2 milk, at milking time, so he would be able to keep the A2A2 milk separate for sale at a higher price. That’s a business person thinking about opportunities.

What is Likely to Happen

It is very likely that private companies with on-farm data and breeding companies wanting to have additional or unique indexes will form alliances for the calculation of new genetic indexes. If they aren’t doing it already, it will happen soon. Definitely, breeding companies working with equipment and service providers would be able to use all the data from many countries.

In the absence of having industry approved indexes breeders will be faced with using various company indexes. Fully trained geneticists already work for all of the data capture, breeding, service, product and genomic evaluation companies. So it is not a matter of if, but when it will happen.

Time will tell if these new genetic indexes are accurate, useful and understood. One significant question is – “Once the move to private is started will it continue to also include the current national evaluations for production, type, health and fertility traits?”.

In short “the horse is out of the barn”, there will be widespread availability of privately calculated genetic indexes in the future.

The Bullvine Bottom Line

Dairy cattle breeders can expect to see, read or hear sales reps promoting their sires based on new indexes. Is that good? The Bullvine predicts the answer is YES. Well, yes, provided that the indexes will assist breeders to improve the genetic merit of their cattle for lifetime profit.

 

 

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Biggest Ever Cattle Genotyping Project to Help Breed Better Animals

The Irish Cattle Breeding Federation (ICBF) has appointed Weatherbys Ireland DNA Laboratory working in conjunction with Eurofins Genomics to test one million cattle samples over the next 2 years.

The ambitious project is the first anywhere in the world to genotype one million cattle. The test itself uses a microarray technology to measure 55,000 variable positions in the DNA of each animal.

From this, scientists will use this information to predict traits such as fertility, milk yield and meat quality in individual animals.

The work is part of the Beef Data Genomics Program (BDGP), running from 2015 to 2020, launched earlier this year by Ireland’s Minister for Agriculture Food and Marine, Simon Coveney. The ICBF is aiming to genotype one million cattle by 2017, and a further million by 2020.

Ronan Murphy, Weatherbys Ireland CEO, said: “This project is a huge step forward in agri-genomics and we are delighted to have been selected to carry out a testing regime that has never been done on this scale before.

“The microarray chip we will be using has taken two years of development by Weatherbys Ireland DNA laboratory, the ICBF and Teagasc (Irish agriculture and food development authority). By teaming up with Eurofins Genomics, we are able to provide expertise and accredited laboratories at the scale needed to provide customers with new and more efficient services for their animal breeding needs.”

Bruno Poddevin, Senior Vice President, Eurofins Genomic Services, said: “Eurofins Genomics is proud and delighted to have been selected, together with Weatherbys’ DNA Laboratory, to provide its expertise in the world’s largest cattle genotyping project-to-date.

“Through our combined industrial capabilities and highly-skilled DNA experts, Eurofins aims to provide customers in the food and agri-genomics markets the highest quality and most cost-efficient solutions for their animal-breeding needs.

“We are excited to provide our unparalleled capabilities and lend our expertise in large-scale project, and help put Ireland and its farmers at the forefront of genetic testing globally.”

Source: The Dairy Site

Sire Summaries Now Being Processed by Council on Dairy Cattle Breeding

CDCB_logo[1]Following a two-year transition, U.S. sire and genomic evaluations are being done by the Council on Dairy Cattle Breeding (CDCB), as part of the A Non-funded Cooperative Agreement (NFCA) between the Animal Genomics and Improvement Laboratory (AGIL), United States Department of Agriculture and the Council on Dairy Cattle Breeding (CDCB)

The evaluations had previously been done by the United States Department of Agriculture’s Animal Genomics and Improvement Laboratory (AGIL) in Beltsville, Md.

The agreement to transfer the evaluations to CDCB was signed in March, 2013, with the goal of having the transfer complete within two years. “After two years of investments and intense preparation, the transition has been completed,” says Joao Durr, CDCB CEO. “Since Friday, December 11th, 2015, all data processing for genetic evaluations is being conducted by six permanent staff and two contractors at the CDCB.”

For its part, AIGL will continue to do research and develop methods to better compute estimates of genetic merit of dairy cattle, Durr says.

Read more here

CDCB seeks non-voting, advisory board members

image001[1]The Council on Dairy Cattle Breeding (CDCB) is now accepting applications for non-voting, advisory members of the CDCB Board of Directors who are able to provide meaningful insight, guidance and perspective to the Board’s work within dairy industry and fulfill usual board member responsibilities regarding attendance and participation.

Individuals (or organizations that desire to nominate an individual) are encouraged to apply by completing the application form (https://www.cdcb.us/News/Application%20Non-voting%202016.docx) and submitting the application no later than Friday, January 15, 2016, 4:00 pm EST.

Industry Leadership in Feed Efficiency Research

There’s a new buzz word in the dairy cattle industry around the world… “Feed Efficiency”. What is this trait? How is it measured? What is the Canadian industry doing in this area? Let’s take a closer look.

What is Feed Efficiency?

In dairy production, we feed cows primarily to produce milk and its components. Some cows need to eat more to produce the same amount of output as other cows that eat less. This difference among dairy cows is a function of their “efficiency” to convert “feed” nutrients into milk and its components, therefore called Feed Efficiency. Given that cows in different herds consume different feed rations, the measurement of feed intake is standardized in units of dry matter intake. A cow with better feed efficiency will produce more kilograms of milk, fat and protein per kilogram of dry matter intake consumed. Interest in Feed Efficiency has grown in recent years since it contributes to higher profit margins while also decreasing the production of methane emissions that negatively affect the environment.

Factors Affecting Feed Efficiency

The dietary energy that a dairy cow consumes is used for various purposes including body maintenance, growth, pregnancy and milk production. Therefore, factors that affect any of these body functions can also affect feed efficiency. Examples include the number of days in milk during a lactation, a cow’s age since she is usually still growing in first lactation, the type of forages in the diet, and stress or disease experienced by the cow.

How is Feed Efficiency Measured?

One of the major challenges with monitoring and improving feed efficiency is the recording of accurate data in terms of both input and output. To start with, dry matter intake needs to be measured accurately for each cow in the herd and include both the amount of feed provided to each individual cow as well as the amount left over after eating. This is obviously a very expensive process and not feasible on most dairy farms without sophisticated equipment. The output side of the feed efficiency equation is also more complex than generally assumed. Standard milk weights and sample analysis collected by DHI at 4 to 6 week intervals is not accurate enough – daily or weekly data is required. In terms of expressing each cow’s performance for feed efficiency, one strategy is to simply use the actual dry matter intake measured throughout the lactation. This approach is sub-optimal since dry matter intake is highly correlated to milk production, which makes sense since high producing cows need to consume more feed. To solve this problem, the overall consensus amongst scientists globally is the use of Residual Feed Intake (RFI) when assessing feed efficiency. RFI is simply the difference in dry matter intake between a cow and her herdmates after adjusting for the energy used for milk production, body weight and changes in body weight over time.

Canadian Feed Efficiency Research Initiative

On behalf of its industry partners, Canadian Dairy Network (CDN) prepared a 4-year research proposal aimed at improving feed efficiency and reducing methane emissions in Canadian dairy cattle using genomic evaluation and selection. The total project budget is $10.3M, including a total contribution of $860,000 from CDN, and Genome Canada approved financial support totalling $3.8M. The research will be led by Dr. Filippo Miglior, Chief of Research and Strategic Development at CDN and Adjunct Professor at the University of Guelph, while Dr. Paul Stothard, Professor at the University of Alberta is project co-leader. There are a several critical
components to this research project including:

  • Consolidating dry matter intake and methane emissions data collected for groups of dairy cows in Canada, Australia, United Kingdom, Switzerland and United States into a common database at CDN;
  • Establishing a database of genotypes for all cows with feed efficiency and/or methane emissions performance data;
  • Quantifying the accuracy of milk mid-infrared spectroscopy data as a predictor of feed efficiency and methane emissions in dairy cattle;
  • Development of genetic and genomic evaluation systems at CDN for Feed Efficiency and Methane Emissions that would be used for genomic selection of young bulls by A.I. organizations in Canada; and
  • Assessment of the social benefits, costs and acceptance towards genomic selection for feed efficiency and reduction of methane emissions.

Given the importance of accurate data collection towards the success of the major research initiative, one of the major project partners is GrowSafe Systems Ltd., located in Airdrie, Alberta (www.growsafe.com). GrowSafe has developed and manufactured equipment to accurately collect daily feed intake on an individual cow basis. In addition to this type of data being collected in two state-of-the-art research herds in Canada, one owned by the University of Guelph and the other by the University of Alberta, the project proposal includes the involvement of two producer-owned dairy operations that include 200 or more milking cows. CDN is in the process of seeking out those two producers for this important project so those interested should contact CDN.

Summary

Dairy cattle producers around the world have a growing interest to improve the feed efficiency of their animals since it has a major impact on herd profitability. The dairy industry has also an increased awareness of the importance of reducing methane emissions from dairy production from an environmental and social perspective. On behalf of the dairy cattle improvement industry in Canada, CDN has taken the leadership role in developing a major research initiative, involving international partners, that targets the use of genetics and genomics for improving feed efficiency and reducing methane emissions in dairy cattle. This project has received $3.8M in
funding from Genome Canada and will involve the collection of accurate individual cow feed intake data and genotypes from two research herds and two producer-owned herds in Canada. The ultimate goal is the implementation by CDN of new genetic and genomic evaluation systems for these traits in the coming years.

Source: Canadian Dairy Network

December 2015 Proposed Changes to US Evaluation System

Genetic variance for Jersey type traits

By Jan Wright

The genetic SD of several conformation traits will decrease by about 5% in Dec 2015 for Jerseys because an array overflow had affected the iterative herd variance adjustments for that breed only. The program bug had caused almost no change in PTA rankings, only the small changes in SD. Formulas for net merit will not be affected. New and previous SD for each trait are compared below.

Changes in Jersey genetic standard deviation for December 2015
Trait: New Genetic SD Previous Genetic SD
Final score 0.91 0.91
Stature 1.28 1.40
Strength 0.87 0.94
Dairy Form 0.93 0.98
Foot angle 0.70 0.76
Rear leg (side view) 0.63 0.68
Rump angle 1.05 1.11
Rump width 0.76 0.82
Fore udder attachment 1.09 1.16
Rear udder height 1.06 1.13
Rear udder width 0.98 1.04
Udder depth 1.43 1.51
Udder cleft 0.77 0.83
Front teat placement 1.04 1.12
Teat length 0.93 1.02

 

Unknown parent group definitions

By Paul VanRaden, Jay Megonigal, Curt Van Tassell, and Mel Tooker

The automated system to assign unknown parent groups was revised to improve stability and convergence with data updates. The new group definitions are applied to yield traits, productive life (PL), somatic cell score (SCS), daughter pregnancy rate (DPR), heifer conception rate (HCR), and cow conception rate (CCR). Since Dec 2014 the animal model includes pedigrees for young animals, but too few cows with data were included in the most recent groups, so those groups will be combined. Genomic PTAs should change little because most parent averages were recomputed as needed, but parent averages for young, non-genotyped animals with missing sires or dams are the most affected.

Additional breeds from Interbull

By Paul VanRaden and Gary Fok

Bulls with breed codes MO (Montbeliard), NO (Normande), SM (Simmental), and Fleckvieh (FL) will be on the Simmental scale in the Interbull multitrait across-country evaluation (MACE) instead of the Holstein scale. As a result, about 7,000 foreign MO, NO, SM, and FL bulls will be converted by MACE onto the U.S. Holstein base. PTAs for bulls of those breeds will include the expected heterosis when mated to Holstein cows and be comparable to Holstein evaluations, as previously. The MACE system does not exchange fertility PTAs for those breeds, and conformation traits on U.S. scale are not available, so Holstein birth year averages are substituted for the missing traits. Reliability improves for the foreign bulls with U.S. daughters because of more pedigree information and additional ancestor PTAs from MACE for the additional breeds.

Editing changes for sire conception rate

By Duane Norman

An edit previously used in the calculation of sire conception rate (SCR) was if the expected calving date (last breeding date plus 280 days) was 21 or more days greater than the actual subsequent calving date, the breeding was deleted because it was assumed the date was recorded wrong or the service was to a cow already pregnant. However, the average heat cycle is 21 days but individual heats can vary by a few days. According to Ray Nebel (personal communication), “the industry uses 18 to 24 as the normal estrous interval.” Therefore CDCB is changing this edit from 21 to 17 days to allow for the variation expected in the heat cycle.   The gestation period previously used in editing was 280 days; this is being modified to use the gestation period appropriate for the specific breed addressed, i.e., changed to the breed average in the literature (AY, 282; BS, 288; GU, 286; HO, 279; JE, 280; MS, 281; and WW, 280 days). These breed averages were obtained from national data from 1999 through 2006 (Norman et al., J. Dairy Sci. 92(5):2259–2269, 2009).

Another edit previously programmed in SCR was “A herd needed a conception rate between 10 and 90% over the entire 4 year period or the inseminations from the herd were not used” (Kuhn and Hutchison, J. Dairy Sci. 91(6):2481–2269, 2008 and Kuhn et al., J. Dairy Sci. 91(7):2823–2835, 2008). This range seems extreme so we are lowering this on the top to 75% to make it more in line with other procedures being used.

The number of age categories for SCR will be reduced in the Jersey breed to make them resemble more closely a smooth biological curve.

How Do I Use Pro$ for Cows and Heifers?

Pro$ was introduced in August 2015 as a new national genetic selection index in the Holstein and Jersey breeds, in addition to a modified LPI formula. A.I. organizations, breed associations and other industry organizations have embraced this new index that targets producers that earn essentially all of their farm revenue from milk sales. So far, extension has focused on interpreting sire Pro$ values. But what about females? Canadian Dairy Network (CDN) also calculates and publishes Pro$ values for cows and heifers. Learn how they can be used in your breeding program.

How Do I Use Pro$ -1Pro$ for Sires

Pro$ ranks bulls based on the expected average accumulated profit their daughters will achieve until they reach six years of age. There are various ways for sires to achieve high Pro$ values and rankings depending on the ability of their daughters to produce and reproduce well over multiple lactations and experience fewer problems that would otherwise increase herd expenses.

When developing the Pro$ index, CDN felt it was important that the Pro$ difference between sires was directly related to the extra lifetime profit to six years that the daughters would generate for Canadian producers. For this reason, the scale used for Pro$ is specifically in Canadian dollars.

Let’s look at an example with the current #1 proven sire compared to the #40 proven sire for Pro$. The #1 sire has a Pro$ of $2200 while the #40 sire has a Pro$ of $1700. This means that, on average, daughters of the #1 sire are expected to generate about $500 more profit per daughter over their lifetime up to six years of age (Example 1). The take home message here is that sire Pro$ values directly represent the average difference in profit that their daughters are expected to earn up to the age of six years.

How Do I Use Pro$-2Pro$ for Females

On the female side, Pro$ can be used in two distinct ways. On one hand, Pro$ values for cows can be interpreted in the same way as described above for sires. In this context, you must compare Pro$ values between two or more cows and these differences will directly reflect the expected difference in lifetime profit that future replacement heifers, daughters of those cows, would generate for your herd (Example 2). In your herd, your highest Pro$ cows, based on their genetic evaluations for production, conformation and functional traits, will have values that are hundreds of dollars higher than the average of your herd. These cows, on average, are expected to produce the most profitable replacement heifers for your herd.

How Do I Use Pro$-3A second way to use Pro$ values for females is to compare them for heifers born within the same months or year. In this context, the goal is to identify heifers that are expected to be more profitable over their lifetime to six years of age. When comparing Pro$ values for heifers, the differences in Pro$ values need to be doubled to reflect the expected differences in realized accumulated profit to six years. For example, a heifer that has a Pro$ value that is $500 higher than another one is expected to accumulate, on average, $1000 more profit over its lifetime up to six years of age (Example 3).

Animal’s Transmitting Ability Versus Genetic Merit

While it may seem confusing to interpret Pro$ values differently for cows compared to heifers, you simply need to remember why you are using Pro$. When selecting sires or comparing Pro$ among cows in your herd, your focus is producing the most profitable replacement heifers possible. Since the primary use of Pro$ is for sire selection, it has been expressed in a manner that represents the genetics that the animal, sire or cow, is expected to transmit to its progeny, on average. In this way, Pro$ values are considered as the animal’s “Transmitting Ability”.

When considering Pro$ values among a group of young heifers, the objective is to get a better understanding of each heifer’s own “Genetic Merit”, which means doubling the Pro$ values that are expressed as a Transmitting Ability. Doubling Pro$ values for heifers represents how they are expected to perform, on average, as cows in a herd with typical management. Actual lifetime profit realized by each animal can clearly be different due to the significant impact of herd management levels and other non-genetic factors that can affect a cow’s expression for production, conformation and functional traits.

Summary

Pro$ is a selection index that allows producers to improve the lifetime profitability of the dairy herd. The scale of expression for Pro$ values allows direct comparison between sires to easily understand the expected differences in profit of their daughters. This is also true when comparing Pro$ for cows since differences reflect the average lifetime profit their daughters are expected to achieve as future replacements. Since Pro$ is expressed as a “Transmitting Ability”, the values need to be used differently when comparing among a group of heifers. In this case differences need to be doubled in order to serve as a prediction of differences in their future accumulated profit in a herd with typical management.

Source: Canadian Dairy Network

Possible Government Shutdown of CDCB

National news raises the possibility of a U.S. Government shutdown on October 1, 2015. One of the consequences of a shutdown is that all Government computer systems, including AGIL, would be turned off for the duration of the shutdown. The CDCB and AGIL are joint devoting significant resources to speed up the transfer of the Cooperator’s database and the genetic evaluation software to the CDCB servers, but the transition will not be completed by September 30. In order to ensure the release of the October 2015 monthly genomic evaluation, we will be adhering strictly to our published deadline and only data uploaded by Friday, September 25, 11:59 p.m. EST will be included in the run. This includes pedigree corrections uploaded by nominators. This should guarantee that a normal release can happen on October 6, regardless of whether or not a Government shutdown occurs.

A second consequence is that the weekly preliminary genomic prediction to be released on September 29 will include only those genotypes uploaded by Friday, September 25, 11:59 p.m. EST. Data uploaded later will be included in following week’s predictions.

CDCB apologizes for any disruption or extra work this may cause our service users, but CDCB is working to minimize the consequences of a situation beyond our control. Hopefully the political impasse can be resolved and the shutdown avoided.

When all operations have been switched to CDCB servers by the end of the year, such interruptions should not occur

Age at First Calving and Profitability

Whether you’re milking 50 or 500 cows, heifer rearing represents a significant cost to any dairy operation – one that is typically second only to feed costs. What’s more, a heifer spends her first lactation paying for herself, generally not making you money until second lactation. Research has shown that the single most important factor influencing heifer rearing costs is age at first calving. Using cow profitability data, CDN examined the influence of age at first calving on lifetime profit in the four breeds of largest population in Canada.

Average Age at First Calving – How are we doing?

Trends in age at first calving are shown for Holstein, Ayrshire, Jersey and Brown Swiss in Figure 1. From around 2003 to 2006 there was a slight increase in the average age at first calving for all breeds. This was likely associated with border closures due to BSE, leading producers to wait longer to calve heifers due to an industry-wide oversupply of cows. Since this time, however, the average age at first calving has been decreasing steadily in all breeds. From 2006 to 2014, the average first calving age in Holsteins has dropped 1.4 months to the current average of 25.8 months. Interestingly, this is the same average age at first calving for Jerseys – a breed that reaches puberty one to two months earlier than the other breeds represented. In general, age at first calving is higher in the Ayrshire and Brown Swiss breeds, which average 27.2 and 26.7 months, respectively.

Age at First Calving and Profitability figure 1

Age at First Calving and Profitability

Using DHI cow profitability data, CDN calculated profit to six years of age for a subset of roughly 690,000 Holsteins, 17,000 Jerseys, 17,500 Ayrshires and 4,000 Brown Swiss cows born from 2005 to 2008. These profit values take into account rearing cost, cow income and cow expenses. A cut-off of six years of age was used as it proved to capture each cow’s ability to survive through multiple cycles of reproduction, health, functional conformation and production – an imperative feature when looking at lifetime profitability.

Figure 2 shows how average profit to six years varies based on the age at first calving for Holsteins. As mentioned above, the national average first calving age for this breed currently sits at around 26 months. However, the data suggests that 22 months of age is the ideal time for Holstein heifers to calve in order to maximize their future lifetime profitability. Interestingly, and in accordance with research, calving Holstein heifers before 22 months contributes to decreased total lifetime profit.

Age at First Calving and Profitability figure 2

The most profitable age at first calving may differ to some degree between breeds. For example, the analysis reveals that the most profitable first calving age for Holstein and Jersey is 22 months whereas for Ayrshire and Brown Swiss, it is 23 months (Table 1). What also varies by breed is the amount of extra profit per cow to be gained by decreasing the age at first calving from the current breed average to the most profitable age. For example, the amount of lifetime profit lost due to calving one typical Holstein heifer at 26 months compared to 22 months amounts to $880, on average. Assume a 100 cow herd calves 30 replacements per year, most of them at 26 months. If the same herd calved even 10 of the 30 replacements at 22 months instead of 26 months, the increased profit to six years for the ten animals that calved earlier would amount to nearly $9,000!

While all breeds could benefit from reducing their average age at first calving, the greatest benefits could be reaped by the Brown Swiss breed. Of the four breeds studied, the average first calving age is the highest for Brown Swiss and Ayrshire heifers at 27 months. Profitability in Brown Swiss, however, is more negatively impacted by a higher age at first calving. Calving Brown Swiss heifers at 23 months, as opposed to 27 months, could lead to an average profit gained of nearly $1,400 per animal.

Age at First Calving and Profitability table 1

The main advantages of lowering age at first calving include reducing rearing costs as well as reducing the amount of time in which the heifer is a drain on farm resources. Disadvantages of lowering the average age at first calving may include a reduction in first lactation milk yield. However, research has shown that despite this possible reduction in first lactation, production per year of herd life is typically increased by lowering the age at first calving. In addition, while the first lactation may be influenced by younger calving ages, future lactations, longevity and health are not, as long as first calf heifers freshen at an adequate weight.

Since each dairy operation has its own set of unique management and environmental conditions, it may not be possible for all herds to attain one industry-wide goal for age at first calving. This, however, does not mean that we should not work towards shorter rearing periods by calving heifers earlier – clearly there is profit to be made in doing so. Work with your herd veterinarian to assure you’re meeting defined targets for age at first calving that optimize profitability and are in line with your operations specific management needs.

Source: Canadian Dairy Network

 

Selecting for Profitability in Ayrshires

The recent genetic evaluation release in August marked the introduction of a new formula for the Lifetime Performance Index (LPI) in each breed as well as the new Pro$ (Pro Dollars) index for the Holstein and Jersey breeds. If Pro$ is the ideal profit-based genetic selection index, how come it wasn’t introduced for Ayrshires as well? This decision was made over the course of multiple meetings during the past few years involving the Ayrshire Canada Breed Improvement Committee and Canadian Dairy Network (CDN). The bottom line is that the new LPI formula for the Ayrshire breed has been specifically designed to mimic essentially the same result as if Pro$ had been implemented. Let’s take a closer look.

Cow Profitability to 6 Years of Age

The extensive analysis carried out by CDN to develop Pro$ required the calculation of actual profitability values for cows in various breeds. For Ayrshires, accumulated profit over each cow’s lifetime until the age of six years was calculated for 17,400 cows born from 2005 to 2008. Cow profitability values were calculated based on the same economic parameters and equation used by Valacta and CanWest DHI for producing the Profitability Reports they provide to their clients on an annual basis. In addition to the heifer rearing costs from birth to first calving, the income generated from milk sales, as well as the associated expenses, were estimated based on each cow’s production performance accumulated during each lactation until reaching six years of age. For cows that left the herd before this age, the revenue and expenses accumulated to the age at disposal determined the lifetime profit. Using profit accumulated to six years of age allows each cow the opportunity to express up to four cycles of reproduction, calving, health, functional conformation and production performance.

Sire LPI Versus Average Daughter Profit

Once individual cow profitability values were calculated, CDN examined the relationship between a sire’s LPI and the average accumulated profit to six years of age of their daughters. Figure 1 shows this relationship for the current LPI formula introduced for Ayrshires in August.

Selecting for Profitability in Ayrshires figure 1

There are two main points demonstrated by this graph. Firstly, there is a strong correlation of 79% between a sire’s LPI in August 2015 and the realized average daughter profit to six years of age, based on the group of cows analyzed born from 2005 to 2008. This high degree of relationship indicates that LPI is currently an excellent indicator of the expected lifetime profit of an animal’s daughters. In fact, one might say this correlation is outstanding given the many nongenetic factors that can affect a cow’s lifetime profitability, especially herd management and other environmental influences.

Secondly, we can learn from this chart how to translate current LPI values for sires into expected differences in profit of their daughters. For Ayrshire sires, every 100-point increase in LPI translates to an extra average profit to six years of age of $150 per daughter! One way to look at this interpretation of LPI values is to compare the extra cost for a dose of semen for higher ranking LPI sires relative to the expected lifetime profit the daughters of the higher LPI sire will generate.

LPI Versus Pro$ in Ayrshires

During the course of developing Pro$, CDN applied the resulting equation to Ayrshires as well as the other dairy breeds in Canada. Given the strong relationship between LPI and the average daughter profit to six years of age, it was ultimately decided not to introduce a second national genetic selection index for Ayrshires. In fact, if Pro$ was introduced for the Ayrshire breed in August it would have a correlation of 98.7% with the published LPI values for proven sires. Stated in another way, only one of the current Top 20 LPI proven sires would not be among the top 20 if sorted by Pro$ and only minor reshuffling in their specific order would exist. Ayrshire breeders interested in making genetic selection decisions that target maximum profit from milk sales can use the current LPI rankings with confidence.

Expected Response from LPI Selection

One of the critical components of the educational campaign designed to communicate the new Pro$ to Holstein and Jersey breeders is the concept of “expected response” (Figure 2).
Selecting for Profitability in Ayrshires figure 2
Basically, all traits of interest in dairy cattle improvement tend to be genetically correlated to each other to some extent. Some traits may be positively correlated, meaning that selection for one trait will lead to a correlated improvement in the second trait as well. For other traits that have an antagonistic genetic relationship, such as production yields and fertility, specific attention must be made to apply selection for both at the same time or else one will fall behind as the other improves. Therefore, to understand the genetic progress you can expect from selection using an index like LPI, the best tool is the expected response per trait as shown in Figure 2. Clearly, selection for LPI in Ayrshires will produce the highest gains for production yields but significant gains can also be expected for Herd Life, Conformation, Mammary System, Feet & Legs, Dairy Strength and Somatic Cell Score. For most other traits, some genetic gain is expected through selection purely for the new LPI. Two exceptions are Milking Speed and Daughter Fertility due to the negative correlations they have with other traits of importance. For example, in the Ayrshire breed, Daughter Fertility is negatively correlated with the major type traits in addition to the usual antagonistic relationship with production yields that is common to
all breeds. Therefore, with high importance placed on production and type improvement in the breed, it is difficult to also achieve genetic improvement for Daughter Fertility without significantly increasing the emphasis on this trait in the LPI formula. Fortunately, among the current list of high ranking LPI proven sires in the breed, several have above-average proofs for Daughter Fertility.

Summary

The primary goal of every dairy producer, regardless of breed, is profitability. In August 2015 the Holstein and Jersey breeds introduced Pro$ as a second selection index since it differed significantly from the LPI formula in those breeds. Ayrshire breeders can directly use LPI for genetic selection to maximize cow and herd profitability since it is 98.7% correlated to Pro$ if it had been introduced. Using LPI, every 100-point difference between Ayrshire sires translates to an average extra profit per daughter of $150 to six years of age. Expected response resulting from selection for LPI is favourable for essentially all traits of interest with significant gains achievable for the main production and conformation traits as well as resistance to mastitis and longevity.

Source: Canadian Dairy Network

Nordic – China Collaboration on Common Holstein Reference Population for genomic prediction

A strong collaboration on common reference population for genomic prediction has been established among College of Animal Science and Technology (CAST), China Agriculture University, Dairy Association of China, Center for Quantitative Genetics and Genomics (QGG), Department of Molecular Biology and Genetics, Aarhus University, and VikingGenetics. Nordic Cattle Genetic Evaluation, is an associated partner.
The aim of this exiting Chinese and Nordic Collaboration is to strengthen Chinese and Nordic Holstein breeding through enhanced use of genomic selection, which will have great importance in a number of aspects:

  • Faster improvements in Chinese Holstein breeding will be achieved by significantly higher reliabilities of genomic evaluations
  • The Dairy Association of China sees the collaboration as a quantum leap for Chinese Holstein breeding to increase the benefit from genomic selection in China
  • The Nordic bulls can be assessed accurately on the Chinese scale
  • Precise genomic evaluation of Nordic Holstein bulls will have a great export advantage for VikingGenetics
  • China can import and VikingGenetics can export semen from bulls which can perform optimally under Chinese production environments by taking genotype by environment interactions into consideration
  • The model developed in this cooperation will be a framework for VikingGenetics to increase market competitiveness in other countries
  • University partners CAST and QGG will collaborate on new scientific improvements based on the joint data
  • The agreement will support the existing, fruitful collaboration between QGG and CAST, which has already resulted in 12 joint PhD projects among which 3 students have achieved degrees from both universities.

All partners see the collaboration as a great possibility to combine scientific and commercial forces within genomic selection to the benefit of Holstein breeding in China and the Nordic countries.

Council on Dairy Cattle Breeding industry meeting

CDCB_logo[1]The Council on Dairy Cattle Breeding will be hosting its 2015 Industry Meeting on September 29, 2015 at the Madison Marriott West Hotel & Conference Center. Dairy farmers and representatives from all sectors of the dairy breeding industry are welcome to attend in connection with the World Dairy Expo activities. The program (attached) consists of an initial update on CDCB progress and plans ahead and two discussion panels, one addressing the status of dairy cattle breeding research in the U.S. and the other celebrating the landmark of one million genotypes on a reflection about how genomics re-shaped the dairy industry. All interested to participate are gently requested to complete an online pre-registration form prior to attending (follow the link: https://www.rsvpmenow.com/rsvpbeta/?id=27444). The deadline to register is September 18, 2015 at midnight EST.

We hope that you can join us and we look forward to your presence.

Italian August 2015 Genetic Evaluations

italianproofsThere is a new #1 PFT sire in Italy and it’s Heidenskipster Selleck with a +3537 gPFT. He is a Cashcoin son out of the Heidenskipster Silver’s, going back on the American brood cow, Morningview Converse Judy.  He is followed by KNS Brasilero a Balisto son from the Epic daughter KNS Reality. The former #1 gPFT bull Holbra Doorman Rodanas will be find on the 4th place currently.

Discovering Genetic Anomalies from Genotyping

Genotyping a single animal has direct advantages in terms of providing a genomic evaluation for genetic selection and mating as well as confirming its parentage for herdbook integrity. Accumulating thousands of genotypes for a population of animals in a breed has become an excellent source for identifying various genetic anomalies, which are usually undesirable. Although the discovery of an undesirable gene in a breed is initially viewed negatively, the new knowledge provides an opportunity to monitor the frequency over time and eventually eradicate it from the active population, especially among A.I. sires.

Haplotypes Impacting Fertility

Due to the growth of genotyping in North America since it began in 2008, the Canadian Dairy Network (CDN) database now includes over 800,000 Holstein genotypes and more than a million across all dairy breeds. This extensive database of DNA profiles allows scientists to follow the transmission of short sections of DNA strands, called haplotypes, from parent to progeny across generations. To date, given the number of genotyped animals in each breed, various “Haplotypes Impacting Fertility” have been identified including five in Holsteins (HH1 to
HH5), two in each of Jersey (JH1 and JH2) and Brown Swiss (BH1 and BH2) and one in Ayrshires (AH1). The impact of these haplotypes in each breed, which generally cause early embryonic death, depends on the frequency of the associated gene in the population and especially the percentage of active A.I. sires that are carriers. Any negative impact of these genetic anomalies can be eliminated by avoiding the mating of carrier sires to carrier heifers and cows, which is best achieved using computerised mating programs offered by A.I.

New Holstein Haplotype Discovered

Very recently, a group of research scientists in Germany discovered a new haplotype in the Holstein breed. Unlike the previously found “Haplotypes Impacting Fertility”, this particular genetic anomaly was found to be associated with calf survival in the first months of life. For calves that inherited the undesirable gene from both parents, it was found that they had an increased incidence of chronic/prolonged diarrhea that was untreatable, as well as other illnesses. Examination of blood samples from affected calves showed a cholesterol deficiency that prevented the normal deposition of fat in body tissues. Over the course of months after birth, the affected calves lost all body reserves and it appears that all eventually died.

In an attempt to identify the specific gene responsible for this newly identified genetic anomaly, the German scientists were successful in showing the inheritance pattern and the gene location being on chromosome 11. While the specific gene has not yet been located, a short series of SNPs, referred to as a haplotype, has been identified that is consistently present in the genotypes of carrier animals. Pedigree analysis of carriers has shown they all trace back to Maughlin Storm, born in 1991, as the oldest common genotyped sire. The popularity of Storm, as well as several of his outstanding sons and grandsons that are carriers, eventually spread the associated gene to many Holstein populations globally, which explains this discovery in Germany. Since the negative impact of this genetic anomaly, namely early calf death, only happens for calves that inherit the gene from both parents (i.e.: two descendants of Storm mated together), it takes multiple generations of breeding to discover.

A Complicating Factor

Unfortunately, without having an exact gene test for this genetic anomaly, determining the carrier status can be complicated for some animals. The haplotype identified in Storm and his carrier descendants also exists in Willowholme Mark Anthony (born in 1975) but he does not carry the specific undesirable gene. The presence of the common haplotype stems from the fact that Mark Anthony’s sire, Fairlea Royal Mark, is also the great maternal grandsire of Storm. It appears that somewhere in the transmission of genes from Fairlea Royal Mark down through the three generations to Storm a form of mutation occurred that caused this genetic anomaly. Without knowing the exact gene, the only tool available for identifying carriers is by using the defined haplotype. This means, however, that animals with both Storm and Mark Anthony in their pedigree may have the defined haplotype but could be falsely identified as a carrier of the responsible gene. Table 1 provides a list of the A.I. sires that are known carriers of this undesirable gene and have more that 5,000 registered daughters born in Canada to date. An animal with any of these sires in its pedigree may also be a carrier and genotyping such animals will help to clarify the carrier status.

Table 1: HCD Carrier Sires with over 5,000 Registered Daughters Born in Canada

Relationship to Maughlin Storm (HOCANM5457798)

Sons

Grandsons

Great Grandsons

PURSUIT SEPTEMBER STORM

BRAEDALE GOLDWYN

GILLETTE WINDBROOK

COMESTAR STORMATIC

GILLETTE FINAL CUT

COMESTAR LAUTHORITY

HARTLINE TITANIC-ET

DUDOC MR BURNS*

GILLETTE STANLEYCUP

LADINO PARK TALENT-IMP-ET

KERNDT STALLION

LIRR DREW DEMPSEY

COMESTAR LAVANGUARD

GOLDEN-OAKS ST ALEXANDER-ET

GILLETTE WINDHAMMER

* Dudoc Mr Burns carries the haplotype with the undesirable gene from Storm as well as the haplotype sourced through Mark Anthony. Therefore, genotyping his progeny will not lead to conclusive results about the carrier status of the undesirable gene.

Carrier Probability Values

Since the initial discovery of the first “Haplotypes Impacting Fertility” CDN has been calculating and publishing “Carrier Probability” values for every animal in the CDN database. Regardless of the breed, the haplotype Carrier Probability values are displayed on the “Pedigree” link from each animal’s “Genetic Evaluation Summary” page on the CDN web site (www.cdn.ca). A displayed probability of 99% identifies animals that are expected to be “Carrier” while a value of 1% indicates they have been identified as “Free” based on the haplotype analysis. Animals not genotyped receive an estimated Carrier Probability that can vary from 99% to 1% depending on the probability values for its parents and other relatives.

In North America, this newly discovered haplotype in Holsteins will be labelled as HCD, meaning “Haplotype associated with Cholesterol Deficiency”. CDN has developed methodology for assigning a Carrier Probability value for HCD based on existing genotypes as well as tracking the source of the undesirable haplotype through pedigree analysis. This strategy allows some genotyped animals that have both Storm and Mark Anthony in their pedigree to be properly identified as “Carrier” or “Free” but for other animals, where this distinction in not possible, a Carrier Probability between 99% and 1% will be published by CDN.

Summary

In addition to genomic evaluations and integrity of pedigrees, accumulating thousands of genotypes for a given breed results in the discovery of new genetic anomalies. Scientists in Germany recently discovered a new “Haplotype associated with Cholesterol Deficiency” (i.e.:HCD) in Holsteins, which traces back to Maughlin Storm as the oldest genotyped sire of origin. Without the presence of an exact gene test to identify carriers, the current haplotype analysis can result in some animals being falsely labelled as a carrier if they have both Storm and Willowholme Mark Anthony in their pedigree. The methodology used by CDN to calculate the HCD Carrier Probability values (varying from 99% for “Carrier” to 1% for “Free”), reduces this problem by combining the haplotype test with pedigree analysis. Now that this undesirable anomaly is known, an industry effort can easily be made to reduce the frequency that carrier animals are mated together, thereby lowering the frequency that homozygous calves are born and subsequently die within months. The discovery of this genetic condition also demonstrates the value and importance of producers reporting to DHI the date and reason for every animal leaving the herd, including young calves.

Dairy Cattle Breeding Is All About Numbers

Dairy cattle farming has many numbers for breeders to review and weight as they go about their daily roles as manager, health care provider, bookkeeper, personnel manager, feed harvester, reproduction sequencer, animal selection or removal supervisor, ….. yes, the daily duty list is long. But in all cases, it is best to use a number when making a decision.

For this article, The Bullvine wishes to focus on the fact that science-based numbers (aka genetic indexes) are the best method to use when selecting the animals to produce the next generation.

Breeding – Is it Art or Science?

Dairy cattle breeders argue both sides of the answer to this question. Some breeders swear by a single observation, their impression or their experience (aka art) while others totally depend on science-based numbers. Let’s dig deeper.

What’s in the Number?

Breeders can use the number they can actually see, like lactation milk yield, or a cow’s milk genetic index that considers factors like age, herd mates, progeny, pedigree and now DNA analysis. The same applies to using a cow’s PTAT rather than her own classification.  It is best to consider all factors.

Can the Number be trusted?

Accuracy is paramount to success or failure in dairy cattle breeding. Making a breeding decision based a single individual observation is 20 to 25 percent accurate in predicting a cow’s progeny’s performance. Using a cow’s genetic index that includes pedigree, DNA analysis and performance will be sixty-five to seventy percent accurate.

Does the Number Mean Anything for You?

Every breeder needs to have a breeding plan (Read more: What’s the plan?) for their entire herd or an individual mating. In the plan, there needs to be the importance of individual traits. Not every trait, for which an index is available, is essential for every herd or mating. Indexes like gTPI and NM$ should be included in every plan.

Breed for Desired Outcome.

Higher Milk Revenue – Do you breed for protein yield or protein percent? Very definitely it is protein yield. It is the volume of protein that breeders are paid for. Higher protein percent is associated with less milk production.

Improving Herd Longevity – Do you select a genomic sire for his PL (Productive Life index) or how long his dam produced milk? Very definitely for his PL.  His dam’s length of life has many non-genetic factors and will have a very low heritability.

Improving Fertility – When mating a heifer do you consider her FI (Fertility Index) or the frequency with which her dam calved? Very definitely her FI.  Her dam’s calving interval has an extremely low heritability, almost zero.

Developing a High Type Herd – Do you select a sire based on PTAT or the number of show winners he produces? Very definitely his PTAT. Show herds do not use a wide spectrum of sires and do not randomly use sires, this results in potentially biased genetic evaluations on the sires they use.  Since many of the sires they are used on are not used in chimerical herds, the evaluations on these sires are biased.  When a “type” sire does cross into wide stream usage you start to see evaluations like Goldwyn’s.  Goldwyn is often noted as a great sire of show winners yet his PTAT of +1.81 and his PL of -0.5 reflects that used across the entire population he does not stand out as a significant improver.

The Bullvine Bottom Line

Genetic improvement depends upon using science to improve accuracy and the completeness of decision making. The rate of genetic advancement has improved significantly over the past decade, and the pace will double again in the next decade. Breeding is about science.

 

 

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CDN: Industry Standards: Why?

Canada is world renowned for having outstanding dairy cattle with superior genetic potential. In 2014, the exports of dairy genetics from Canada exceeded $158M, which was nearly a 30% increase over 2013 and a 43% increase over 2012. The world has confidence in Canadian genetics and the high quality of our animals in terms of production, conformation, longevity and other functional traits. An important part of the confidence stems from the high level of integrity associated with the information published for all dairy animals in Canada.

DHI Options
For over 15 years now, Canadian producers have a wide spectrum of service levels made available to them when enrolled on milk recording. The ultimate goal of DHI services provided by CanWest DHI and Valacta is to provide valuable information for management decisions to maximize cow and herd profitability. The definition of “valuable” can vary from producer to producer and, therefore, so might the type of services they receive from their milk recording agency. Producers may decide if they want monthly herd visits to achieve 12 tests per year or decrease the frequency to 10, 8 or even 6 times per year. At each visit, they can decide if they want to conduct a 24-hour test based on all milkings that day, or if they only want to take milk weights and samples for one milking, from which a 24-hour yield is estimated using national
procedures applied consistently across the country. Over and above all these options, producers can also decide if they want to involve milk recording staff on test day to conduct supervised testing instead of the herd owner recording each cow’s milk production on test day and collecting milk samples for sending to the DHI laboratory for component and somatic cell count analyses.

Publishable Lactations
Depending on the milk recording services a herd receives, the lactations for each cow may be officially published by Canadian Dairy Network (CDN) for the world to see or they may only be reported back to the producer for management purposes only. Not every producer sees the value in having “publishable” lactations and they are therefore not prepared to pay for the higher level of milk recording services required to meet the standards for official publishablility.

In Canada, there are approximately 960,000 dairy cows spread across 12,000 herds, which equates to an average of 80 cows per herd. Of these, 700,000 (73%) cows in 9,000 (75%) herds are voluntarily enrolled on some level of milk recording service. Based on the choices made by herd owners, 54% of the herds enrolled on DHI have decided to meet the national standards required for the official publication of lactations. These herds represent nearly 60% of the cows on milk recording. Publishable lactations are made publicly available on the CDN web site and distributed to the breed associations for public access on web sites, official pedigrees,
sale catalogues, etc. Publishable lactations are the basis for calculating official herd average production levels as well as for inclusion in the calculation of various awards including Master Breeder, Star Brood Cow points, Superior Production, Lifetime Production Certificates and other recognitions at the cow and herd levels. In general, herds enrolled on DHI service levels that meet the requirements for publishable lactations will also end up with official genetic evaluations for production traits published by CDN. Classified cows with official production indexes will also receive official type indexes as well as an official LPI and, starting in August 2015, they will also receive an official Pro$ value, which is the new genetic selection index for the Holstein and Jersey breeds in Canada.

Official Publication Requires National Standards
Herd owners that opt to enroll on DHI at services levels that result in officially published lactations and genetic evaluations can benefit significantly from the world exposure this brings to their cows, herd and breeder’s prefix. The integrity of the data published is dependent upon the way that Canada ensures the national standards are met by all herd owners involved with supervised testing. These standards are established by an industry committee under the leadership of CDN and administered at the field level by DHI. On behalf of the dairy cattle improvement industry, CanWest DHI and Valacta use various indicators to monitor milk recording data collected from herds involved with supervised testing and/or qualifying for genetic
evaluations. Part of this data analysis involves identifying herds that have individual cows performing at very high levels and/or have very high herd average production levels. Checks are also done comparing milk weights recorded on test day to the amount of milk shipped from the bulk tank. Any combination of these data indicators may trigger a mandatory retest of a herd, without prior notice, immediately following a regularly scheduled test day. On occasion, any herd may also be selected for conducting such a retest, simply to ensure the overall integrity of Canada’s system for publishing official lactations. All herd owners enrolled on milk recording services that involve supervised testing and/or qualify for inclusion in genetic evaluations, are subject to the terms, conditions and obligations of the Canadian service standards manual. Herein, it is clearly written, among other things, that herd owners must:
• Uniquely and accurately identify each cow in the herd,
• Test all milking cows in the herd on each test day,
• Maintain the same schedule of milking and animal milking order on test day as on other days,
• Maintain the same herd management practices on test day as on other days,
• Assure the accuracy and completeness of all information collected and recorded,
• Not engage in any activity that may mislead, impair or attempt to impair the reliability of any information about an animal or the herd,
• Use approved milk-metering devices and corresponding sampling devices, and
• Accept any retest, without prior notice, at the time and date determined by the milk
recording agency.

In the event that any of the above obligations are not fully respected by the herd owner, appropriate disciplinary actions have been established by CDN for application by the milk recording agencies in a consistent manner across the country. CDN also has procedures in place for herd owners to subsequently appeal any imposed disciplinary sanction, which would then be reviewed by a group of independent producers also enrolled on DHI services with publishable lactations.

Freedom of Choice
For the most part, Canadian producers fully understand and respect the industry standards currently in place relative to the official publication of lactation records. For herd owners wishing to use lactation records only for internal herd management decisions, the same standards do not apply. It is a choice of each producer to decide if they want to receive publishable lactation records and official genetic evaluations for their cows. When electing to do so, however, they also become part of the national system for data verification to ensure the integrity of all lactations that become publicly accessible to the world. These lactations also form the basis of
the major awards given to Canadian producers and breeders for the outstanding performance and genetic potential of their cattle and herds.
Author: Brian Van Doormaal, General Manager, CDN
Date: June 2015

Les normes de l’industrie: pourquoi?
Le Canada est reconnu à l’échelle mondiale comme ayant des bovins laitiers remarquables dotés d’un potentiel génétique supérieur. En 2014, l’exportation de produits génétiques laitiers du Canada a dépassé les 158 M$, ce qui représente une hausse de près de 30 % par rapport à 2013 et de 43 % par rapport à 2012. Le monde fait confiance à la génétique canadienne et à la grande qualité de nos animaux sur le plan de la production, la conformation, la longévité et les autres caractères  fonctionnels. Une part importante de la confiance découle du niveau élevé d’intégrité associé à l’information publiée pour tous les animaux laitiers au Canada.

Options de contrôle laitier
Depuis maintenant plus de 15 ans, les producteurs canadiens ont accès à un large éventail de niveaux de services lorsqu’ils s’inscrivent au contrôle laitier. Le but ultime des services de contrôle laitier offerts par Valacta et CanWest DHI est de  fournir des renseignements précieux pour la prise de décisions de gestion visant à maximiser la rentabilité des vaches et des troupeaux. La définition de « précieux » peut varier d’un producteur à l’autre et, par conséquent, il en va de même pour le type de services qu’ils reçoivent de leur agence de contrôle laitier. Les producteurs peuvent décider s’ils souhaitent recevoir des visites mensuelles pour réaliser douze
tests par année ou diminuer la fréquence à dix, huit ou même six fois par année. À chaque visite, ils peuvent décider s’ils veulent réaliser un test de 24 heures basé sur toutes les traites effectuées ce jour-là, où s’ils souhaitent seulement prendre les pesées et les échantillons de lait d’une seule traite, à partir desquels un rendement de 24 heures sera évalué au moyen de procédures nationales appliquées de façon uniforme dans l’ensemble du pays. En plus de toutes ces options, les producteurs peuvent aussi décider s’ils souhaitent que le personnel du contrôle laitier effectue des tests supervisés lors du jour du test au lieu que ce soit le propriétaire du troupeau qui enregistre la production de lait de chaque vache le jour du test et qui recueille les échantillons de lait pour les envoyer au laboratoire de contrôle laitier en vue d’une analyse des composants et des cellules somatiques.

Lactations publiables
Selon les services de contrôle laitier que reçoit un troupeau, les lactations de chaque vache peuvent être officiellement publiées par le Réseau laitier canadien (CDN) de façon à ce que le monde entier les voie, ou elles peuvent être retournées au producteur à de seules fins de gestion. Ce ne sont pas tous les producteurs qui perçoivent la valeur des lactations « publiables » et ils ne sont donc pas prêts à payer pour un niveau plus élevé de services de contrôle laitier requis pour répondre aux normes relatives aux lactations publiables officielles.

Le Canada compte approximativement 960 000 vaches laitières réparties dans 12 000 troupeaux, ce qui équivaut à une moyenne de 80 vaches par troupeau. De ce nombre, 700 000 (73 %) vaches dans 9 000 (75 %) troupeaux sont soumises sur une base volontaire à un certain niveau de service de contrôle laitier. Selon les choix effectués par les propriétaires de troupeaux, 54 % des troupeaux inscrits au contrôle laitier répondent aux normes nationales exigées pour la publication officielle des lactations. Ces troupeaux représentent près de 60 % des vaches soumises au contrôle laitier. Les lactations publiables sont accessibles au public dans le site web de CDN et elles sont distribuées aux associations de race en vue de leur accès public dans les sites web, les généalogies officielles, les catalogues de vente, etc. Les lactations
publiables servent de base au calcul de la moyenne des niveaux officiels de production des troupeaux et sont incluses dans le calcul de différentes reconnaissances, y compris le titre de Maître-éleveur, les points d’Étoile, les certificats de Production supérieure et de Production à vie, ainsi que d’autres reconnaissances décernées aux vaches et aux troupeaux. De façon générale, les troupeaux inscrits aux niveaux de services de contrôle laitier qui répondent aux
exigences des lactations publiables obtiendront aussi des évaluations génétiques officielles pour les caractères de production publiées par CDN. Les vaches classifiées avec des indices en production officiels obtiendront aussi des indices en conformation officiels ainsi qu’un IPV officiel et, à partir d’août 2015, elles obtiendront aussi une valeur Pro$ officielle, qui est le nouvel indice
de sélection génétique dans les races Holstein et Jersey au Canada.

La publication officielle exige des normes nationales
Les propriétaires de troupeaux qui choisissent de s’inscrire aux niveaux de services de contrôle laitier qui permettent d’obtenir des lactations et des évaluations génétiques publiées officiellement peuvent profiter grandement du degré d’exposition mondiale qu’elles procurent à leurs vaches, à leur troupeau et à leur préfixe d’éleveur. L’intégrité des données publiées dépend de la façon dont le Canada s’assure que les normes nationales sont respectées par tous les propriétaires de troupeaux participant aux tests supervisés. Ces normes sont établies par un comité de l’industrie sous la direction de CDN et sont administrées sur le terrain par le contrôle laitier. Au nom de l’industrie de l’amélioration des bovins laitiers, Valacta et CanWest DHI utilisent différents indicateurs pour contrôler les données du contrôle laitier recueillies dans des troupeaux participant aux tests supervisés et/ou admissibles aux évaluations génétiques. Une partie de cette analyse de données consiste à identifier des troupeaux où des vaches réalisent des rendements individuels à un niveau très élevé et/ou atteignent des niveaux de production très élevés par rapport à la moyenne du troupeau. Des vérifications sont aussi effectuées afin de comparer les pesées de lait enregistrées lors du jour du test aux quantités de
lait expédiées du réservoir à lait. Toute combinaison de ces indicateurs de données peut déclencher un test à l’improviste obligatoire pour un troupeau, sans avis préalable, immédiatement après le jour du test de l’horaire régulier. À l’occasion, un troupeau peut aussi être sélectionné afin de subir un test à l’improviste, simplement pour s’assurer de l’intégrité globale du système canadien de publication des lactations officielles.

Tous les propriétaires de troupeaux inscrits aux services de contrôle laitier qui comportent des tests supervisés et/ou des données admissibles aux évaluations génétiques sont assujettis aux modalités, aux conditions et aux obligations du manuel canadien des normes de service. Dans ce manuel, il est clairement indiqué que les propriétaires de troupeaux doivent, entre autres :
• Identifier de façon unique et précise chaque vache dans le troupeau,
• Soumettre au test toutes les vaches en lactation dans le troupeau lors de chaque jour du test,
• Maintenir lors du jour du test le même horaire de traite et le même ordre de traite des animaux que celui utilisé les autres jours,
• Maintenir lors du jour du test les mêmes pratiques de gestion du troupeau que celles
utilisées les autres jours,
• Assurer la précision et l’intégralité de toute l’information recueillie et consignée,
• Ne pas se livrer à des activités qui pourraient induire en erreur, compromettre ou tenter de compromettre la fiabilité de tout renseignement sur un animal ou un troupeau,
• Utiliser des appareils de mesure du lait approuvés et des appareils d’échantillonnage
correspondants,
• Accepter tout test à l’improviste, sans avis préalable, à l’heure et à la date fixées par
l’agence de contrôle laitier.

Advenant que le propriétaire du troupeau ne respecte pas entièrement les obligations décrites ci-dessus, des mesures disciplinaires appropriées ont été établies par CDN en vue de leur application par les agences de contrôle laitier de façon uniforme dans l’ensemble du pays. CDN dispose aussi de procédures permettant aux propriétaires de troupeaux d’en appeler subséquemment de toute sanction disciplinaire imposée, et cet appel serait alors étudié par un groupe de producteurs indépendants aussi inscrits aux services de contrôle laitier avec des lactations publiables.

Liberté de choix
Dans l’ensemble, les producteurs canadiens comprennent bien et respectent les normes de l’industrie actuellement en vigueur en ce qui concerne la publication officielle des relevés de lactation. Les mêmes normes ne s’appliquent pas dans le cas des propriétaires de troupeaux qui souhaitent utiliser les relevés de lactation uniquement pour des décisions de gestion interne du troupeau. Il appartient aux producteurs de décider s’ils souhaitent recevoir des relevés de lactation publiables et des évaluations génétiques pour leurs vaches. Toutefois, lorsqu’ils choisissent de le faire, ils font aussi partie du système national de vérification de données visant
à assurer l’intégrité de toutes les lactations qui deviennent publiquement accessibles à l’échelle mondiale. Ces lactations forment aussi la base des principales reconnaissances décernées aux producteurs et aux éleveurs canadiens pour le rendement et le potentiel génétique remarquables de leurs bovins et de leurs troupeaux.
Auteur : Brian Van Doormaal, directeur général, CDN
Date : Juin 2015

New Zealand to Include BCS in Breeding Values

Breeding Worth provides farmers with an economic measure of genetic merit (profit per five tonne of dry matter) and is calculated for all dairy cattle. During a National Breeding Objective Review in 2012, BCS (particularly late lactation BCS) was identified as an important trait with economic value to farmers.

NZ Animal Evaluation Ltd (NZAEL), a wholly-owned subsidiary of DairyNZ, estimates the economic value of BCS to be $106 per BCS score. It was also determined that rates of genetic gain in BW would be enhanced by the inclusion of the BCS breeding trait. This view is supported by national and international review.

NZAEL manager Dr Jeremy Bryant says the economic value of BCS comes from two components.

“The first and main component is the increased value of a cow with good conditionmilking well into late lactation, rather than drying her off early because she is too thin.

“The second component is the reduced cost of a cow maintaining condition, as compared to a cow that loses condition in the spring, and as a result requires more feed through autumn or winter when it is more expensive.”

Dr Bryant says that both of these components are based on the value of increased body condition score in late lactation rather than early in lactation.

“With this in mind, it important that the breeding value for this trait represents genetic differences between animals in late lactation.

“Our studies showed there were minimal differences between breeds in late lactation BCS, especially between Friesians and Jerseys, and farmers often make decisions to dry off cows based on both BCS and breed. Because of this, the BCS breeding value will be breed neutral, so it is more aligned to a late lactation equivalent,” says Jeremy.

A ‘breed neutral’ adjustment will be applied to the breeding value and will come into effect in June 2015 and BCS will be included in the BW calculation from February 2016.  

For further information visit www.dairynz.co.nz/bcs-bw.

Pro$: Genetic Selection for Profit

Fill in the blank: When making genetic selection decisions, my ultimate goal is to create a ___________ cow. If you filled in the blank with the word “profitable”, a new tool is on the way that will be of interest to you. Over a year of research has led to the development of a new genetic selection index that will allow Canadian dairy producers to improve their herd profitability.
Why do we need a second national index?

This index was developed by Canadian Dairy Network (CDN) over the past year following an industry request to explore the possibility of developing a second national index that targets dairy producers who generate essentially all of their farm revenue from milk sales. The newly developed, profit-based index has been named “Pro$” (pronounced Pro Dollars), and has officially been approved for release in August 2015. Pro$ will be available in the Holstein and Jersey breeds, while other dairy breeds will use the research behind the development of Pro$ to modify their existing LPI formula to better reflect profit.

The development of Pro$
The backbone of Pro$ is cow profitability data from Valacta and CanWest DHI – data that comes directly from Canadian dairy farms. This information is provided to their customers across Canada in the form of a Cow Profitability Report as well as a Herd Summary Profitability Report. The economic parameters used to derive the profitability values for each cow are updated annually by economists in order to assure their relevancy.

Using the cow profitability formula derived by Valacta and CanWest DHI, CDN calculated the accumulated profit to six years of age for nearly 700,000 Holstein cows born from January 2005 to September 2008. This time period was chosen in order to give each cow the opportunity to reach six years of age when the analysis was conducted at the end of 2014. If cows did not survive to six years of age, their accumulated profit until the date they left the herd was considered as their lifetime profit. While profit can be accumulated to any age, or to each calving, the decision to define profit to six years of age allows each cow the opportunity to express its ability to survive through multiple cycles of reproduction and production, which is important for defining which traits are most important contributors to lifetime profitability. Once the accumulated profit was calculated for each animal, the cows were grouped by sire to calculate the average profit of its daughters to six years of age.

The final step required to develop Pro$ involved performing a statistical regression analysis, which is a technical way of saying sire proofs for various traits were used as input to predict the average daughter profit to six years. Sires were only included if they had at least 100 daughters with profit data, leading to a total of 830 Holstein sires analyzed. Using regression analysis allowed CDN to consider the genetic relationships among all traits to determine the contribution that sire evaluations for each trait have in terms of predicting the average profit of their daughters in a scientifically sound and objective way.

Interpreting bull ratings for Pro$
Pro$, the “Pro” standing for “profit”, will be expressed in dollars and as a deviation from breed average. In other words, sires with a Pro$ of $0 are expected to produce daughters that have an average accumulated profit to six years that is equivalent to the average cow in Canada, which is approximately $2500 for Holsteins. Likewise, bulls with a Pro$ of $1000, can be expected to sire daughters that have an average accumulated profit to six years that is $1000 higher than daughters of the average Pro$ bull. In other words, selecting sires with a higher Pro$ value will directly translate to increased lifetime profit of the resulting daughters. This concept is illustrated in Graph 1 and Figure 1 below. If your herd is better managed than the average herd in Canada, your herd’s average accumulated profit to six years may be higher than the national average but the interpretation of the difference between the Pro$ values for two sires remains equal across all herds.

CDN-Graph1-Figure1[1]

 

LPI and Pro$ – Similarities and Differences
Effective August 2015, the updated LPI formula for Holsteins will have relative weights of 40%, 40% and 20%, respectively, on the Production, Durability (longevity and functional conformation), and Health & Fertility components. Also of importance is the inclusion of the new Mastitis Resistance index introduced in August 2014 into the LPI formula. Taking these LPI updates into consideration, what can you expect as a result of selecting for Pro$ compared to LPI?

First off, it is important to realize that lifetime profit can be defined differently from farm to farm, depending on the sources of revenue and associated expenses. While Pro$ is targeted to meet the needs of producers who generate essentially all their revenue from milk sales, LPI retains the interests of those who market genetics domestically and abroad. Compared to LPI, using Pro$ as your primary selection tool will maximize production yields, longevity and overall fitness. On the other hand, using LPI as your primary selection tool will lead to a herd with exceptional conformation and fat and protein deviations. No matter which index you align yourself with, you can be confident that all of the information that feeds the traits in each index is sourced directly from Canadian dairy farms.

So which proven sires top the charts for Pro$? Table 1 shows the sires that would currently rank in the Top 15 for Pro$ as well as their rank for the current LPI. Examining the two lists reveals 10 out of 15 bulls are in common. Five bulls ranking in the Top 15 for Pro$ rank outside of the Top 15 for LPI, as is indicated by the shaded cells in the LPI rank column.

CDN-Table1[1]

 

The differences in ranking between the two lists above highlight some of the differences between the two indexes and may help producers better align themselves with the index that serves their goals. Over a year of research has led to the development of Canada’s new profit-based index, Pro$, to be released for the first time with the August 2015 official genetic evaluation run. The provided background on the creation of Pro$, the explanation of Pro$ proof interpretation, and the comparison between Pro$ and LPI should allow Canadian producers to feel confident in this new and innovative genetic selection tool.

Authors: Lynsay Beavers, Industry Liaison Coordinator, CDN and Brian Van Doormaal, General Manager, CDN

Pro$:  sélection génétique en vue du profit

Complétez l’énoncé suivant : lorsque je prends des décisions en matière de sélection génétique, mon but ultime est de créer une vache ___________. Si vous avez rempli l’espace avec le mot « rentable », un nouvel outil bientôt disponible saura vous intéresser. Plus d’une année de recherche a mené au développement d’un nouvel outil de sélection génétique qui permettra aux producteurs laitiers canadiens d’améliorer la rentabilité de leur troupeau.

Pourquoi avons-nous besoin d’un deuxième indice national?
Le Réseau laitier canadien (CDN) a élaboré cet indice au cours de la dernière année à la suite d’une demande de l’industrie visant à explorer la possibilité de développer un deuxième indice de sélection ciblant les producteurs laitiers dont essentiellement tous les revenus à la ferme proviennent de la vente de lait. L’indice nouvellement conçu, basé sur le profit, a été appelé « Pro$ » (se prononce Pro Dollars) et il a été officiellement approuvé en vue de son lancement en août 2015. Pro$ sera disponible dans les races Holstein et Jersey, alors que les autres races laitières utiliseront la recherche derrière le développement de Pro$ pour modifier leur formule d’IPV existante afin de mieux refléter le profit.

Le développement de Pro$
La pierre angulaire de Pro$ repose sur les données de rentabilité des vaches fournies par Valacta et CanWest DHI – des données qui proviennent directement des fermes laitières canadiennes. Cette information est fournie à leurs clients dans l’ensemble du Canada sous la forme d’un Rapport de rentabilité des vaches ainsi que d’un Rapport sommaire de rentabilité de troupeau. Les paramètres économiques utilisés pour établir les valeurs de rentabilité de chaque vache sont actualisés chaque année par des économistes afin d’en assurer la pertinence. En utilisant la formule de rentabilité des vaches établie par Valacta et CanWest DHI, CDN a calculé le profit accumulé jusqu’à l’âge de six ans par près de 700 000 vaches Holstein nées de janvier 2005 à septembre 2008. Cette période a été choisie de façon à donner à chaque vache la possibilité d’atteindre l’âge de six ans lorsque l’analyse a été réalisée à la fin de 2014. Si les vaches ne survivaient pas jusqu’à six ans, leur profit accumulé au moment où elles ont quitté le troupeau était considéré comme leur profit à vie. Même si le profit peut être accumulé jusqu’à n’importe quel âge, ou jusqu’à chaque vêlage, la décision de définir le profit à l’âge de six ans donne à chaque vache la possibilité d’exprimer sa capacité de survivre à de multiples cycles de reproduction et de production, ce qui est important pour définir les caractères qui contribuent le plus à la rentabilité à vie. Une fois que le profit accumulé a été calculé pour chaque animal, les vaches ont été regroupées en fonction de leur père en vue du calcul du profit moyen de ses filles jusqu’à l’âge de six ans.

L’étape finale exigée pour l’élaboration de Pro$ consistait à effectuer une analyse statistique de régression, ce qui est une façon technique de dire que les épreuves des taureaux pour différents caractères ont été utilisées comme données de départ pour prédire le profit moyen des filles jusqu’à six ans. Les taureaux n’étaient inclus que s’ils avaient au moins 100 filles avec des données de profit, ce qui a mené à l’analyse de 830 taureaux Holstein au total. L’utilisation d’une analyse de régression a permis à CDN de considérer les corrélations génétiques entre tous les caractères en vue de déterminer la contribution qu’apportent les évaluations des taureaux pour chaque caractère sur le plan de la prédiction du profit moyen de leurs filles de façon scientifiquement rigoureuse et objective.

Interprétation du classement des taureaux selon Pro$
Pro$, où « Pro » désigne le « profit », sera exprimé en dollars et en tant qu’écart par rapport à la moyenne de la race. En d’autres mots, les taureaux dotés d’un Pro$ de 0 $ devraient engendrer des filles ayant un profit accumulé à six ans qui équivaut à celui de la vache moyenne au Canada, soit approximativement 2 500 $ chez les Holstein. De même, on peut s’attendre à ce que les taureaux avec un Pro$ de 1 000 $ engendrent des filles dont le profit moyen accumulé à six ans sera de 1 000 $ supérieur par fille à celui des filles d’un taureau Pro$ moyen. De cette manière, la sélection de taureaux dotés d’une valeur Pro$ supérieure entraînera directement
une augmentation du profit à vie de leurs filles. Ce concept est illustré au Graphique 1 et à la Figure 1 ci-dessous. Si votre troupeau est mieux géré que le troupeau moyen au Canada, le profit accumulé moyen des vaches de votre troupeau jusqu’à l’âge de six ans pourrait être plus élevé que la moyenne nationale, mais l’interprétation de la différence entre les valeurs Pro$ de deux taureaux demeure égale d’un troupeau à l’autre.CDN-Graph1-Figure1[1]

IPV et Pro$ – similitudes et différences
À partir d’août 2015, la formule d’IPV modifiée chez les Holstein comportera des pondérations relatives respectives de 40 %, 40 % et 20 % pour les composants de Production, de Durabilité (longévité et conformation fonctionnelle) et de Santé et Fertilité. L’inclusion du nouvel indice de Résistance à la mammite introduit en août 2014 dans la formule d’IPV revêt aussi de l’importance. Compte tenu de ces actualisations de l’IPV, à quoi pouvez-vous vous attendre à la suite de la sélection en fonction de Pro$ par rapport à l’IPV?

Tout d’abord, il est important de réaliser que le profit à vie peut être défini différemment d’une ferme à l’autre, selon les sources de revenus et les dépenses associées. Alors que Pro$ vise à répondre aux besoins des producteurs dont les revenus proviennent essentiellement de la vente de lait, l’IPV suscite l’intérêt de ceux qui commercialisent des produits génétiques au pays et à l’étranger. Par rapport à l’IPV, l’utilisation de Pro$ comme principal outil de sélection maximisera les rendements en production, la longévité et les caractères fonctionnels. D’autre part, l’utilisation de l’IPV comme principal outil de sélection fera en sorte que le troupeau affichera une conformation exceptionnelle ainsi que des différentielles de gras et de protéine supérieures. Quel que soit l’indice que vous adopterez, vous pouvez avoir bon espoir que toute l’information qui alimente les caractères dans chaque indice provient directement de fermes laitières canadiennes.

Quels taureaux éprouvés dominent le classement selon Pro$? Le Tableau 1 indique quels taureaux devraient actuellement se classer parmi les 15 meilleurs pour Pro$ ainsi que leur rang actuel selon l’IPV. Un examen des deux listes révèle que 10 taureaux sur 15 sont les mêmes. Cinq taureaux classés parmi les 15 meilleurs selon Pro$ ne figurent pas parmi les 15 meilleurs pour l’IPV, comme l’indiquent les cellules ombragées dans la colonne du classement de l’IPV.

CDN-Table1[1]

Les différences de classement dans les deux listes ci-dessus font ressortir quelques-unes des différences entre les deux indices et pourraient aider les producteurs à mieux se positionner par rapport à l’indice qui répond à leurs objectifs. Plus d’une année de recherche a mené à l’élaboration du nouvel indice canadien basé sur le profit, Pro$, qui sera publié pour la première fois lors de la ronde d’évaluations génétiques officielles d’août 2015. Le contexte de la création de Pro$, les explications sur l’interprétation des épreuves Pro$ ainsi que la comparaison entre
Pro$ et l’IPV devraient permettre aux producteurs canadiens d’avoir confiance en cet outil de sélection génétique nouveau et novateur.

Auteurs : Lynsay Beavers, coordonnatrice de la liaison avec l’industrie, CDN and Brian Van Doormaal, directeur général, CDN

Proof terminology explained

The numbers, letters and acronyms on a proof sheet can be confusing and overwhelming, even for the genetic enthusiasts. Here you’ll find an explanation of the separate indexes, as well as definitions and explanations of proof and linear traits.

Click on a proof trait or selection index below to find the definition for that trait or index.

General TPI
NM$

CM$
MACE
CDCB
GFI%
aAa
DMS
Production PTA
PTAM
PTAP
PTAF
CFP
PRel
HealthPL
DPR
SCS
SCE  |  DCE
SSB  |  DSB
HCR  |  CCR
HRel
ConformationPTAT
UDC
FLC
TRel
Recessives & haplotypesBY-TY
CV-TV
BL-TL
DP-TD
MF-TM
HH1  |  HH2
HH3  |  HH4
HH5
Genetic codesPO
PC
PP
RC
DR


Selection index definitions

While we advocate that each producer sets their own customized genetic plan to put emphasis only on the traits that matter to them, the following are industry standard indexes used to help the average dairy producer increase profitability on their farm.


TPI = Total Performance Index
TPI is calculated by the Holstein Association USA (HA-USA) and includes the following trait weightings.

Trait weights for Total Performance Index (TPI)


NM$ = Net Merit Dollars
NM$ is a value that describes the expected lifetime profit per cow as compared to the base of the population born in 2005. Trait weightings are updated approximately every five years and include emphasis on the following traits.

Trait weights for the Net Merit $ (NM$) Index


CM$ = Cheese Merit Dollars
CM$ is an index calculated to account for milk sold to be made into cheese or other products. The following trait weights are considered.

Trait weights for the Cheese Merit $ (CM$) Index


MACE = Multiple-trait Across Country Evaluation
Denotes that a bull’s proof evaluation includes daughter information from multiple countries


CDCB = Council on Dairy Cattle Breeding, calculates production and health trait proof information


GFI% = Genomic Future Inbreeding percentage


aAa = Read more about this breeding guide HERE.


DMS = Dairy Mating Service.  Read more about it HERE.


Production traits


PTA = Predicted Transmitting Ability
The estimate of genetic superiority or inferiority for a given trait that an animal is predicted to transmit to its offspring. This value is based on the animal’s own records and the records of known relatives.


PTAM = Predicted transmitting ability for milk


PTAP = Predicted transmitting ability for protein, shown in pounds and percent


PTAF = Predicted transmitting ability for milk fat, shown in pounds and percent


CFP = Combined fat and protein


PRel = the percent reliability for a sire’s production proof


Conformation traits


PTAT = Predicted transmitting ability for type, also referred to as conformation


UDC = Udder composite index, which is comprised of the following trait weights:

  • 35% Udder Depth
  • 16% Fore udder attachment
  • 16% Rear udder height
  • 12% Rear udder width
  •   9% Udder Cleft
  •   7% Rear teat placement
  •   5% Front teat placement


FLC = Foot and leg composite index, which is comprised of the following trait weights

  • 50% foot and leg classification score
  • 24% foot angle
  • 18.5% rear legs rear view
  • 7.5% rear legs side view


TRel = the percent reliability for a sire’s conformation/type proof


Health and calving traits


PL = Productive life
Measured as the total number of additional or fewer productive months that you can expect from a bull’s daughters over their lifetime.  Cows receive credit for each month of lactation, with more credit given to the first months around peak production, and less credit given for months further out in lactation. More credit is also given for older cows than for younger animals.


DPR = Daughter pregnancy rate
Daughter Pregnancy Rate is defined as the percentage of non-pregnant cows that become pregnant during each 21-day period. A DPR of ‘1.0’ implies that daughters from this bull are 1% more likely to become pregnant during that estrus cycle than a bull with an evaluation of zero. Each increase of 1% in PTA DPR equals a decrease of 4 days in PTA days open.


SCS = Somatic cell score
The log score of somatic cells per millilitre.


SCE = Sire calving ease
The percentage of births of bull’s calves that are considered difficult in first lactation animals


DCE = Daughter calving ease
The percentage of a bull’s daughters who have difficult births during their first calving


SSB = Sire stillbirth
The percentage of a bull’s calves that are born dead to first lactation animals


DSB = Daughter stillbirth
The percentage of a bull’s daughters who give birth to a dead calf in their first lactation


HRel = the percent reliability for a sire’s health trait proof numbers


HCR = Heifer Conception Rate
A virgin heifer’s ability to conceive – defined as the percentage of inseminated heifers that become pregnant at each service. An HCR of 1.0 implies that daughters of this bull are 1% more likely to become pregnant as a heifer than daughters of a bull with an evaluation of 0.0


CCR = Cow Conception Rate
A lactating cow’s ability to conceive – defined as the percentage of inseminated cows that become pregnant at each service. A bull’s CCR of 1.0 implies that daughters of this bull are 1% more likely to become pregnant during that lactation than daughters of a bull with an evaluation of 0.0.


Genetic codes


PO = Observed polled  |  PC = Tested heterozygous polled  |  PP = Homozygous Polled


RC = Carries recessive gene for red hair color  |  DR = Carries dominant gene for red hair color


Undesirable Recessives, Tested Free codes, and haplotypes


BY = Brachyspina  |  TY = Tested free of Brachyspina


BL = Bovinve Leukocyte Adhesion Deficiency (BLAD)  |  TL = Tested free of BLAD


CV = Complex Vertebral Malformation (CVM)  |  TV = Tested free of CVM


DP = Deficiency of the Uridine Monophosphate Synthase (DUMPS)  |  TD = Tested free of DUMPS


MF = Mulefoot  |  TM = Tested free of Mulefoot


HH1
HH2
HH3    = Holstein haplotypes that negatively affect fertility
HH4
HH5

Source: Alta Genetics

Twenty Years of CDN!

May 2015 marks CDN’s 20th anniversary; 20 years of providing leadership in dairy herd improvement through genetic evaluation services and an information infrastructure that are envied around the world. The company was officially incorporated on May 29th, 1995 as the result of the privatization of national genetic evaluation services from the federal government to industry. CDN member organizations include breed associations, milk recording agencies and A.I. companies marketing genetics in Canada, as well as Dairy Farmers of Canada (DFC). CDN
is fully funded by its industry member organizations with an annual operational budget approaching two million dollars in addition to over $400,000 per year to support genetics research in universities across Canada. The Board of Directors consists of eight representatives from the member organizations, with the vast majority being dairy producers.

CDE-photo-300x191[1]

CDN staff from left to right: Front row: Gladys Huapaya, Janusz Jamrozik, Brian Van Doormaal (General Manager), Jamie Zimmerman, Lynsay Beavers, Patti Beaumont (Information Services Manager) Back row: Pete Sullivan, Gerrit Kistemaker (Chief Geneticist), Filippo Miglior (Chief of Research & Strategic Development), Jarmila Johnston, Michela Arbuthnott, Shakeel Ahmad

CDN People
A total of twelve people work at CDN representing three main areas of activity, namely (1) genetic evaluation and research, (2) data processing and industry services and (3) management, administration and communications.

Genetic Evaluation and Research
CDN’s primary mandate is to provide genetic evaluation services for all dairy cattle breeds in Canada. To accomplish this objective with timely and accurate proofs, there are six geneticists  at CDN. Dr. Gerrit Kistemaker has worked at CDN for 16 years and, in his role as Chief Geneticist, he ensures that genetic evaluation systems are executed properly while conducting ongoing research to continually improve existing systems. Gladys Huapaya has been with CDN for 15 years and assists with the calculation of genetic evaluations. New to CDN in the past five years, Drs. Jarmila Johnston and Janusz Jamrozik carry out research activities to address industry concerns and identify improvements in methodology. Dr. Pete Sullivan has been Research Scientist for nearly 10 years and concentrates his time on developing and implementing new methods associated with CDN’s genetic and genomic evaluations but also significantly contributes to the international genetic and genomic evaluation services provided by Interbull. With more than 15 years experience working in the CDN environment, Dr. Filippo Miglior is the Chief of Research and Strategic Development at CDN and is also an Adjunct Professor at the University of Guelph. His activities target industry-driven research priorities by developing new methodologies and tools for implementation by CDN as well as coordinating research projects and securing government funding for major industry initiatives.

Industry Services and Data Management
In addition to genetic evaluation services and research, CDN is responsible for the maintenance of a national dairy database for the exchange of data among industry partner organizations, as well as for public access via the CDN website. As Information Services Manager, Patti Beaumont has nearly 15 years experience at CDN and supervises all activities related to computer hardware, software, database design, data exchange and internet services. Patti is also a database programmer and expert in Oracle, and therefore ensures the proper functionality of the database processes and develops new ones as required.

As Coordinator of Data Exchange and Information Services, Jamie Zimmermann is responsible for the regular receipt and processing of data from milk recording, breeds and A.I. for loading in the CDN database as well as the genotypes for all animals tested in North America. In addition, she coordinates the provision of all data from CDN back to the industry organizations, which is a continual process. Shakeel Ahmad has been the information technology expert at CDN in the role of System and Network Administrator for over 13 years and is responsible for the maintenance of all hardware and software including the powerful computers used for genetic evaluation calculations, research and web queries accessing the CDN database. A new role developed a few years ago is that of Industry Liaison Coordinator. This position is held by Lynsay Beavers who writes articles and gives presentations on topics related to the genetic improvement of dairy cattle. She also interacts directly with industry personnel and producers on matters related to genetic and genomic evaluation services provided by CDN.

Management, Administration and Communications
As General Manager since the creation of CDN twenty years ago, Brian Van Doormaal and Michela Arbuthnott, as Administrative Assistant for the past 8 years, are a solid team that cover all activities related to the management, finances, administration and record keeping for the corporation. Working closely with the Board of Directors, they implement policies and directives and coordinate activities associated with three advisory committees, namely the Dairy Cattle Genetics Research and Development Council (DairyGen), the Genetic Evaluation Board (GEB) and the Industry Standards Committee. CDN is also responsible for the organization of the Dairy Cattle Improvement Industry Forum held in September of each year in conjunction with the CDN Annual General Meeting.

The Future
Today, genetic evaluation systems and services at CDN are highly respected and envied around the world. In this era of genomics, the need for information management is growing while industry partners strive for continued efficiencies. Under the umbrella and structure of CDN, the dairy cattle industry in Canada is well positioned to face the challenges of the future and maintain the profitability of Canadian producers in the years to come.

Les 20 ans de CDN!

Mai 2015 marque le 20e anniversaire de CDN; 20 ans comme chef de file dans l’amélioration des troupeaux laitiers par le biais de services d’évaluation génétique et d’infrastructure de l’information qui suscitent l’admiration dans le monde entier. La compagnie a été officiellement incorporée le 29 mai 1995, à la suite de la privatisation des services nationaux d’évaluation génétique qui sont passés du gouvernement fédéral à l’industrie. Les entreprises membres de CDN sont des associations de race, des agences de contrôle laitier et des compagnies d’I.A.
commercialisant des produits génétiques au Canada, ainsi que les Producteurs laitiers du Canada (PLC). CDN est entièrement financé par ses entreprises membres oeuvrant dans l’industrie, avec un budget d’exploitation annuel de près de deux millions de dollars, en plus d’au-delà de 400 000 $ par année en guise d’appui à la recherche en génétique dans diverses universités au Canada. Le conseil d’administration est formé de huit représentants des entreprises membres, la majorité étant des producteurs laitiers.

Les gens de CDN

Au total, douze personnes travaillent à CDN, réparties dans trois principaux secteurs d’activité, soit (1) l’évaluation génétique et la recherche, (2) le traitement des données et les services à l’industrie et (3) la gestion, l’administration et les communications.

Évaluation génétique et recherche
CDN a pour mission première d’offrir des services d’évaluation génétique à toutes les races de bovins laitiers au Canada. Pour atteindre cet objectif au moyen d’épreuves précises publiées en temps opportun, CDN emploie six généticiens. Dr Gerrit Kistemaker travaille à CDN depuis 16 ans, et en sa qualité de généticien principal, il s’assure que les systèmes d’évaluation génétique sont exécutés correctement tout en poursuivant la recherche afin d’améliorer constamment les systèmes existants. Gladys Huapaya est à CDN depuis 15 ans et elle contribue au calcul des évaluations génétiques. Des nouveaux venus à CDN au cours des cinq dernières années, Dre Jarmila Johnston et Dr Janusz Jamrozik, mènent des activités de recherche visant à répondre aux préoccupations de l’industrie et à identifier des améliorations
dans la méthodologie. Dr Pete Sullivan occupe le poste de chercheur scientifique depuis près de 10 ans, et il consacre son temps à développer et à mettre en oeuvre de nouvelles méthodes associées aux évaluations génétiques et génomiques de CDN, mais il contribue aussi grandement aux services internationaux d’évaluation génétique et génomique fournis par Interbull. Fort d’une expérience de plus de 15 ans dans l’environnement de CDN, Dr Filippo Miglior est le chef de la recherche et du développement stratégique à CDN et il est aussi professeur auxiliaire à l’Université de Guelph. Ses activités visent les priorités de recherche axées sur les besoins de l’industrie par le développement de nouvelles méthodologies et d’outils
à être mis en oeuvre par CDN, ainsi que la coordination de projets de recherche et l’obtention de crédits gouvernementaux pour les initiatives majeures de l’industrie.

Services à l’industrie et gestion des données
En plus des services d’évaluation génétique et de la recherche, CDN est responsable de la maintenance de la base de données nationale en vue de l’échange de données entre les entreprises partenaires de l’industrie, ainsi que de l’accès public par l’entremise du site web de CDN. Dans son rôle de directrice des services d’information, Patti Beaumont possède près de 15 années d’expérience à CDN et elle supervise toutes les activités liées à l’équipement informatique, aux logiciels, à la conception de la base de données, à l’échange de données et aux services internet. Patti est aussi programmeuse de base de données et experte en Oracle, elle s’assure ainsi du bon fonctionnement des processus de la base de données et en développe de nouveaux au besoin.

En tant que coordonnatrice de l’échange des données et des services d’information, Jamie Zimmermann est responsable de la réception et du traitement réguliers des données provenant du contrôle laitier, des races et de l’I.A. en vue de leur chargement dans la base de données de CDN ainsi que des génotypes de tous les animaux testés en Amérique du Nord. De plus, elle coordonne le transfert de toutes les données de CDN aux entreprises de l’industrie, ce qui représente un processus continu. Shakeel Ahmad est l’expert en technologies de l’information à CDN où il assume le rôle d’administrateur du système et du réseau depuis plus de 13 ans, et il
est responsable de la maintenance de tout le matériel informatique et des logiciels, incluant les puissants ordinateurs utilisés pour le calcul des évaluations génétiques, la recherche et les requêtes reçues dans la base de données de CDN. Un nouveau rôle créé il y a quelques années est celui de coordonnatrice de la liaison avec l’industrie. Ce poste est occupé par Lynsay Beavers qui rédige des articles et effectue des présentations sur des sujets liés à l’amélioration génétique des bovins laitiers. Elle interagit aussi directement avec le personnel de l’industrie et les producteurs sur des sujets associés aux services d’évaluation génétique et génomique offerts par CDN.

Gestion, administration et communications
En qualité de directeur général depuis la création de CDN il y a vingt ans, Brian Van Doormaal forme avec Michela Arbuthnott comme adjointe administrative depuis les huit dernières années une solide équipe qui couvre toutes les activités liées à la gestion, aux finances, à l’administration et à la tenue de registres pour la corporation. Travaillant en étroite collaboration avec le conseil d’administration, ils mettent en oeuvre des politiques et des directives, et  coordonnent les activités associées à trois comités consultatifs, soit le Conseil de recherche et développement en génétique des bovins laitiers (DairyGen), le Conseil d’évaluation génétique  (GEB) et le Comité des normes de l’industrie. CDN est aussi responsable de l’organisation du Forum de l’amélioration de l’industrie des bovins laitiers tenu en septembre chaque année,
conjointement avec l’assemblée générale annuelle de CDN.

L’avenir
Aujourd’hui, les systèmes et les services d’évaluation génétique de CDN sont hautement respectés et admirés dans le monde entier. Dans cette ère de la génomique, il existe un besoin croissant pour la gestion de l’information alors que les partenaires de l’industrie s’efforcent de maintenir l’efficacité. Sous l’égide et la structure de CDN, l’industrie canadienne des bovins laitiers est en bonne position pour relever les défis de l’avenir et préserver la rentabilité des
producteurs canadiens dans les années à venir.

Body Condition Score to Enter Breeding Values in New Zealand

The breeding value of some New Zealand bulls will alter when a new trait is integrated into genomic evaluations, worth thousands of dollars to each herd.

The economic impact of Body Condition Score (BCS) has led to its inclusion in the 2016 ‘Breeding Worth’, levy board Dairy New Zealand has announced.

Dairy NZ, the group overseeing the development of the new trait, says the cost is NZ$106.6 per BCS and its inclusion could enhance the rate of improvement in breeding worth.

This was discovered three years ago in the 2012 National Breeding Objective Review where BCS, particularly in late lactation, was identified as an important trait to farmers.

The value of BCS comes in two main components – maintaining milk yield and saving on feed costs.

A DairyNZ spokesperson said: “Firstly, the reduced costs from a cow maintaining or losing less condition as opposed to a cow that loses lots of condition in spring and then has to replenish that condition in autumn or winter when feed is more expensive.

“Secondly, the value of a well-conditioned cow milking well into late lactation, rather than drying her off early for poor condition. These result in an economic value of $106.6 per BCS.”

Breeding value for BCS is calculated from the records of two year old heifers. These are collected in early lactation with the majority coming from industry standard progeny tests.

However, the adjustments mean the “vast majority” of bulls will have a shift in breeding worth of ten units higher or lower, potentially greater in young bulls, warned DairyNZ.

Australia’s new breeding indices

Australia’s new breeding indices are explained in a two minute animation released by ADHIS.
National Breeding Objective – Final Short Report

For the first time, Australian dairy farmers have had a direct say on the next generation dairy herd as part of a review of the National Breeding Objective.

The review has concluded with three new breeding indices to be introduced from April 2015.

    • The APR will be replaced by the Balanced Performance Index (BPI). This is an economic index that achieves overall profit and is in line with farmer preferences.
    • In recognising different breeding philosophies, two additional indices will be introduced; the Health Weighted Index (HWI) and Type Weighted Index (TWI)

Download your copy of the National Breeding Objective Review Final Short Report so that you can follow the journey of the review and find out more about Australia’s new breeding indices.

Source: Holstein Australia

CDN Base Change Summary – April 2015

Each year, the genetic base used to express genetic evaluations in Canada is updated in conjunction with the first official release. The definition of each genetic base used is therefore as follows:

Base Change Summary - April 2015

The table below indicates the amount of base change realized in 2015 compared to 2014 for each trait and breed. For LPI, the following base adjustments reflect the change to the new scale with half the variance compared to previous years.

Base Changes for 2015 Versus 2014

1 – Base change for LPI is set to zero since it is already reflected by the change in the “Constant” included in the LPI formula. 2 – Traits expressed on scale of Relative Breeding Values (RBV). 3 – For Somatic Cell Score only, negative base change values represent a desirable trend in genetic progress.

Canada Introduces its New Profit Index: Pro$

The Canadian Dairy Network (CDN) is pleased to launch a second national genetic selection index starting with the genetic evaluation release in August 2015. This new profit-based index, named Pro$ (pronounced Pro Dollars), has been developed by CDN over the past year following an industry request to explore the possibility of developing a second index that targets dairy producers with essentially all of their farm revenue generated by milk sales. To-date, Holstein Canada and Jersey Canada have indicated formal support for introducing Pro$ in August 2015 for their respective breeds to be published alongside the longstanding LPI. For other dairy breeds, results from the research behind the development of this new profit index will most likely be used to modify the existing LPI formula.

CDN Chairman, Gary Bowers applauded CDN staff, members of the Genetic Evaluation Board (GEB) and industry partners for the development of this new and innovative profit index. He stated “The use of existing cow profitability calculations offered by CanWest DHI and Valacta to their customers as the underlying data for carrying out the scientific analysis to develop the Pro$ formula makes the resulting genetic ratings of sires and cows very applicable and understandable in concrete dollar terms”. “The new Pro$ serves to complement the strength of the LPI nationally and internationally while recognizing that lifetime profit can be defined differently from farm to farm, depending on sources of revenue and associated expenses”, added Bowers.

To minimize any possible confusion between the two national genetic indexes, the CDN Board of Directors also approved a slight name change for LPI, becoming Lifetime Performance Index. While the CDN research has clearly shown that LPI is strongly correlated to lifetime profit, the new profit index optimizes the association between a sire’s Pro$ and the average accumulated profit of daughters to six years of age. In addition, the CDN Board of Directors approved the new LPI formula for Holsteins, effective August 2015, which will have relative weights on the Production, Durability and Health & Fertility components of 40%, 40% and 20%, respectively. For specific traits included in the LPI, the Mastitis Resistance index introduced in August 2014 will now be included within the Health & Fertility component and replace Somatic Cell Score, Udder Depth and Milking Speed, which served as indicator traits associated with udder health.

Canadian Dairy Network (CDN) is the national genetic evaluation centre for dairy cattle and provides services to Canadian dairy producers and member organizations including breed associations, DHI agencies, A.I. organizations and Dairy Farmers of Canada. It also serves as the hub of the national Data Exchange System by which all dairy cattle improvement industry organizations share authorized data collected from dairy herds across the country.

For more information, please contact:
Brian Van Doormaal
General Manager
Canadian Dairy Network

Impact of Genetic and Genomic Evaluation Improvements

The April 2015 genetic evaluation release will include various improvements officially introduced by Canadian Dairy Network (CDN). The combined impact of these changes, which will vary from trait to trait, will be especially important for genomic young bulls and genotyped heifers. What has changed and how should you adjust your selection decisions accordingly?

What has Changed?

In April of each year, CDN updates the genetic base used for the expressing of Canadian genetic evaluations to account for the annual rate of genetic progress for each trait. In addition to this usual adjustment associated with the upcoming genetic evaluation release in April 2015, CDN will also be introducing the following improvements to various components of its genetic and genomic evaluation calculations:

  • The Canadian Test Day Model for production traits has been enhanced to allow for different shapes of lactation curves from herd to herd, which can also change over time within a herd. Herd management practises and environmental effects can affect production levels differently throughout the lactation and therefore affect the shape of lactation curves. This adjustment, which has shown to provide more accurate sire proofs for production traits, will have an important impact on cow evaluations in some herds while other herds will be less affected.
  • The calculation of indexes and associated Reliabilities for Daughter Fertility, Calving Ability and Daughter Calving Ability has been improved in a manner that provides consistency between sires proven domestically and foreign sires with a MACE evaluation in Canada.
  • The prediction for Indirect Herd Life has been updated following the introduction of Mastitis Resistance and Body Condition Score as newly evaluated traits in recent years.
  • For the calculation of genomics, the methodology for de-regressing sire proofs has been significantly improved such that foreign sires with a MACE evaluation contribute to the estimation of genomic evaluations in a manner more consistent to the contribution from domestically proven sires. An important consequence of this new methodology is that it significantly reduces the current over-estimation of genomic young bulls and heifers compared to proven sires and cows.

Although most of the improvements above are specific to certain traits, the enhanced procedure for proof de-regression affects genomic evaluations for all traits to one degree or another.

Impact on Genomic Young Bulls

To demonstrate the impact of these improvements, which will be observed with the April 2015 release, Table 1 shows the average change for all North American genomic young bulls as well as for the Top 100 based on GPA LPI. For most traits, the average impact across all genomic young bulls is relatively small although an overall decrease is observed for production and major type traits as well as Herd Life, which translates to an average LPI drop of 65 points. The average change is more important, however, for high genomic young bulls as indicated by the Top 100 GPA LPI bulls in Table 1. For LPI, these bulls experience an average decrease of 129 LPI points and the traits that drop the most include Conformation, Herd Life, the other major type traits and Fat yield. Similar changes can be expected for genotyped heifers so breeders will have to adjust their criteria for evaluating and selecting the most elite genomic young bulls and heifers in the breed.

Table 1  Average Impact of Genetic and Genomic

Figure 1 shows the relationship for LPI values before and after the April 2015 improvements to the genetic and genomic evaluations, with the dark diagonal line representing values that are equal in each case. The impact of these changes is quite clear with essentially all of the highest genomic young sires reducing to some degree, which is roughly 3% on average for bulls over 3000 GPA LPI and about 2% for bulls between 2500 and 3000. Among genomic young bulls currently over 3000 GPA LPI, essentially 99% will decrease due to the improvements implemented in April with the most extreme changes being as high as -250 LPI points.
figure 1 impact of genomic young bulls in ai
Since Conformation is the trait most affected by the improvements introduced in April 2015, Figure 2 shows the relationship between the before and after genomic evaluations for genomic young bulls in A.I. that are positive for Conformation. As expected, the new methodologies implemented by CDN will reduce the over-estimation of young bulls compared to proven sires and a similar impact will been seen for genotyped heifers. While the average change for the Top 100 GPA LPI young bulls is -2.4 for Conformation (Table 1), the most extreme decreases will be 4 points or more. In addition to this impact, the genetic base update to be implemented in April is expected to result in an overall decrease of close to one point for Conformation for all animals.

figure 2 impact of genomic bulls in ai
Summary

A fundamental principle and mandate of CDN is to provide the most accurate genetic evaluations possible for all dairy breeds in Canada. The arrival of genomics over five years ago has increased the challenges associated with this key objective. CDN geneticists have worked hard in recent years to identify improvements to methods used to calculate traditional genetic evaluations as well as genomic evaluations. Through the process of research and presentation of results to industry partners, various genetic and genomic evaluation improvements will be implemented in April 2015 in addition to the usual annual genetic base update. These improvements have shown to provide more accurate evaluations going forward but will result in a significant one-time adjustment that especially impacts elite genomic young bulls and genotyped heifers. Breeders and industry organizations must adjust their criteria and selection decisions according to the narrowed scale of genomic evaluations at the extreme levels.

Source: CDN

Genetics in the Age of Genomics – Seminar Recordings and Recap

Butlerview, Butler Feller Sales, Jetstream Genetics, Accelerated Genetics and Holstein World combined to put on an outstanding seminar on the current state of dairy cattle breeding.  Titled “Genetics in the Age of Genomics” and held at the beautiful Kierland Weston in Scottsdale Arizona, the seminar consisted of many of the top minds from around the world.  There where speakers from Research, A.I., and producers who combined managed over 30,000 milking cows.

  1. IMG_1541Welcome – Jeff Butler -Butlerview

    Jeff Butler, of Butlerview and Butler Fellers sales welcomes everyone to the Genetics in the Age of Genomics Conference in Scottsdale Arizona. Jeff and his team have brought together some of the greatest minds from across North America to share there thoughts about where the state of the dairy cattle genetics marketplace. Jeff also shares that Ed Fellers a key member of the team is unable to attend.  It was Ed who first introduced Jeff to genomics, telling him that it is Genomics that was going to change the breed.  Then a few weeks later Ed called Jeff and said “You are not going to believe this, but I own part of this bull and he is going to be a great genomic bull”.  His name was Atwood.  Atwood had 5 brothers and he was the last one, everyone else had been in there and taken all the other ones.  But this thing called “genomics” said that Atwood was going to be the best one of them all. In fact Atwood was the first genomic sire the Butler used. And they had some of the first Atwood calves on the ground.  It just so happens that two of them are named Adrianna, and Abrianna.  So as a result of these two early success stories and how Atwood was doing, and how genomics impacted the decisions to use Atwood Jeff was convinced on genomics.  While the old way was working ok, this “new way” was doing away better.(Read more: BUTLERVIEW: The Goals are Simple. The Genetics are Exceptional. and Exciting Times for Butlerview)Listen to how Jeff explains how dairy cattle genetics will help the dairy industry feed the world.

  2. IMG_1551Joao Durr – CEO of the Council on Dairy Cattle Breeding – Update on U.S. Genetic Evaluations: What’s to come?

    Joao Durr shares with us how CDCB operates, some of the major initiatives that they have coming up and how the US genetic evaluation system works as far as an operational sense.  Joao Durr brings a truly international perspective to the world of genetic evaluations having a background that involves many of the top dairy breeding countries as well as working at INTERBUL.

  3. IMG_1592Brian Van Doormal – GM Canadian Dairy Network – Profitable Genetics in Canada: What are your priorities?

    Brian Van Doormal has been the GM of the Canadian Dairy Network since its inception 20 years ago.  Brian highlights how CDN and other industry partners work together to help accelerate the Canadian dairy genetics industry.  Brian also shares with us some of the great work they have been doing to more accurately evaluate profitability, as well as identifying herd and daughter bias in genetics evaluations. (Read more: CANADIAN BULL PROOFS – You’ve Got to Prove It to Use It!)

  4. IMG_1604Dr. Dan Weigel, Zoetis – Genomics and the Commercial Dairyman

    Dr Weigel shares just how genomic testing has changed, but then also how much genomic testing can help all type of dairy operations.  Dr Weigel is able to bring an interesting perspective to the science of genomic testing, but also is a breeder of dairy cattle and able to put the science in a language that all dairy breeders can understand.  One of the key areas the Dr Wiegel shares is just how much performance difference producers can expect, especially based on how well managed their herds are.  During his presentation also makes it interactive for those in attendance, polling the audience about many of the key questions. (Read more: Herd Health, Management, Genetics and Pilot Projects: A Closer Look at ZOETIS)

  5. Breeder Panel Discussion – Our Options for the Future

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    The panel consists of: John Andersen, Double A Dairy (JOHN ANDERSEN – COMMERCIAL and PEDIGREE – Building a Field of Dreams); Greg Andersen, Seagull Bay Dairy (“Breeding for Efficient Production and a Healthy Herd” with Greg Andersen from Seagull Bay – 2014 Holstein USA Distinguished Young Holstein Breeder); Greg Coyne, Coyne Farms; Don Bennink, North Florida Holsteins (NORTH FLORIDA HOLSTEINS. Aggressive, Progressive and Profitable!!). These 4 breeders represent over 30,000 milking cows, and all are invested in genetics and genomics.  This panel that is not afraid to share their thoughts about inbreeding, classification and the type of animals that commercial breeders are actually looking for.

  6. IMG_1629Dr George Wiggans – Research Leader, AIPL/ARS/USDA – Genomics and Where it Can Take Us

    Dr Wigeons shares with everyone the latest stats around inbreeding and genetic advancement. Dr George Wiggans from USDA shared with the group at the Genetics in Age of Genomics Conference that if you look at the top 100 bulls from 2012 (Dec 2012 NM$ compared to Dec 2014 NM$) the results are 94% accurate.

  7. AI Panel Discussion – Where Will the Bulls Come From?

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    A great cross section of sire analysts from many of the top companies, including: Brian Carscadden – Semex Alliance; Paul Trapp – ABS Global; Lloyd Simon – Industry consultant; Ryan Weigal – Accelerated Genetics; Dan Bauer – Genex CRI & Jon Schefers – Alta Genetics. These gentlemen discuss inbreeding, polled, their selection process as well as where the industry is headed.

  8. The International Perspective Panel Discussion

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    To bring some international prospective to the discussion there is Jan DeVries – AI Total; Declan Patten – Australia; Paul Hunt – Alta Genetics.  These gentlemen represent not only many different countries but also many different roles in the industry.  From the COO of one of the largest AI companies, to a very successful entrepreneur to global dairy marketing expert.

  9. Dr. Tom Lawlor – Executive Director of Research & Development Holstein Association USA

    Dr Lawler shares with everyone some of the latest developments at HUSA, as well as an in-depth look into the state of inbreeding, herd profitability, and GTPI’s ability to predict actual profitability.

     

 

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Council on Dairy Cattle Breeding

CDCB Action Items from the CDCB Board Meeting & CDCB Annual Meeting – February 4, 2015

  1. The CDCB board composition has changed.
    1. Four directors were elected for a three year term (2015 through 2017, Class II):
      1. Dan Sheldon, representing the Dairy Records Providers (re-elected)
      2. Marvin Helbig, representing the Dairy Records Processing Centers (first term)
      3. Gordon Doak, representing National Association of Animal Breeders (first term)
      4. Neal Smith, representing Purebred Dairy Cattle Association (re-elected)
    2. The two non-voting, advisory members of the board, Doug Ricke (Zoetis) and Juan Tricarico (Dairy Innovation Center) were also re-elected for another one year term.
    3. A reorganization meeting followed with the election of the new executive board:
      1. Chair: Jay Mattison (DRPs)
      2. Vice-chair: Gordon Doak (NAAB)
      3. Secretary: John Clay (DRPCs)
      4. Treasurer: Neal Smith (PDCA)
  2. The 2015 budget proposal was approved by the board including a review to the CDCB Fee Schedule. Several fees charged by the CDCB for genomic services will be reduced. The revised fee schedule will be published soon and will be effective March 2, 2015.
  3. Since a new system for compensating the DRPC’s has not been established yet, the CDCB will continue payments equivalent to the previous year’s rate for the April 2015 official evaluations.
  4. Starting in April 2015, all bulls with daughters contributing data to the national database will receive CDCB evaluations for calving traits and sire conception rate.
  5. The CDCB will be the exclusive sponsor of the Interbull/JAM Afternoon Symposium: Use of Genomics to Improve Limited and Novel Phenotypes in Animal Breeding to be held on July 12, 2015, in Orlando, Florida.

Update on Proofs for Identical Twin Sires

Identical twins have identical genotypes. Pedigree-based genetic evaluation systems treat identical animals as full-sibs. This strategy was known to be suboptimal since it assumes that identical twins only have 50% of their genes in common, when in reality they have the exact same DNA and identical genotypes.

For purposes of genetic evaluations, identical twins are expected to transmit the exact same genetic potential to their progeny. However, before genomics it was very difficult to prove that animals were genetically identical.

Since the identification of genetically identical animals was no longer an issue in the genomic era, Canadian Dairy Network (CDN) implemented an improved methodology in 2011 for handling proofs of identical males. As long as they were born after April 1, 2006, any pair of sires identified as having identical DNA via genotyping received the same genetic and genomic evaluations. Identical sires that were already progeny proven as of December 2010 continued to be evaluated as if they were regular full brothers.

Identical sires are treated as one individual animal by pooling their daughter information and calculating one domestic genetic evaluation. For example, if one sire in the pair has 300 daughters and its identical brother has 200 daughters, both sires receive the same genetic evaluation based on the combined group of 500 daughters. Pooling daughter information increases the reliability of their combined proof, compared to treating them as full-sibs in the past. The same proof for identical sires is sent to Interbull for the calculation of MACE evaluations on other country scales. Depending on how the other country, say United States for example, handles the MACE evaluation from Interbull in addition to any daughter data that either
brother may have in that country, identical twins may receive differing official evaluations in other countries.

Case Study – Jordan and Jerrick

Identical twins Gillette Jordan and Gillette Jerrick were first progeny proven in August 2010 and ranked #1 and #7 LPI, respectively, including genomics. As a result, they were both returned to active service and widely used across the country, although Jordan was also previously used as a high-ranking genomic young bull. Since these bulls were born prior to April 1, 2006, their proofs remained separate. Now, both have thousands of daughters in lactation and type classified. Although over 80% of their daughter production data is still from first lactation, these bulls serve as an excellent example of how proofs of identical sires evolve over time (Figure 1).

When first proven in August 2010, the bulls had an LPI difference of 278 points based solely on their traditional proof without genomics. Over the following months and years, their traditional proofs fluctuated to some degree, both upwards and downwards, with the largest difference between them exceeding 400 LPI points. As of April 2013, the variation in the LPI scale was halved and the average LPI was increased by 1700 points so the differences between Jordan and Jerrick for LPI and its components were reduced as expected. Once both bulls reached over 1,700 production daughters in May 2014, their LPI difference before including genomics has consistently been less than 100 points.

figure1[1]

Table 1 shows the difference in traditional proofs without genomics between the identical brothers as of December 2014. Jordan is currently 80 LPI points higher than Jerrick, mainly because his production proof still exceeds that of Jerrick’s, but by far less than it did during the first 6 months after these bulls were officially progeny proven. In terms of type traits, the brothers now only differ from each other by one point or less. Being that Health and Fertility traits are generally low heritability, more daughter data in first and subsequent lactations is required in order to reach high levels of reliability. For this reason, more difference between these bulls still exists for traits like Herd Life, Daughter Calving Ability, Temperament, Milking Speed and Mastitis Resistance. It is expected that as the reliability of their proofs for functional traits increases due to the accumulation of daughter information, their evaluations will continue to become more similar over time, as has been the case with Production and Conformation traits.

table1[1]

Summary

The current CDN policy for calculating proofs for genetically identical brothers still raises some controversy and questions from breeders. Based on the observed evolution of traditional proofs for Jordan and Jerrick, excluding genomics, there is no indication that the policy should be altered. Since both bulls have the same genotype, the inclusion of genomic information for official proofs reduces the observed differences in published evaluations even further. Based on their semen usage in Canada, Gillette Stanleycup and Gillette Windhammer, and possibly Gillette Wildthing and Gillette Willrock, are two other pairs of identical brothers that may serve as case studies in the future but it will take a few more years before they have thousands of daughters with sufficient data for first and subsequent lactations.

Authors: Lynsay Beavers, Industry Liaison Coordinator, CDN Brian Van Doormaal, General Manager, CDN

New fertility traits in Dec. 2014 lead to adjustment in TPI formula will be implemented in April 2015

With the December 2014 national dairy genetic evaluations, USDA and the Council on Dairy Cattle Breeding (CDCB) introduced a new method of measuring Daughter Pregnancy Rate (DPR), along with other model enhancements. The old definition of DPR was number of Days Open, which was then converted to a pregnancy rate within a 21-day cycle. Days open was measured from the end of the voluntary waiting period to either a confirmed pregnancy or 250 days-in-milk. The new definition is an actual observation of pregnancy; a series of “no” or “yes” measures at 21-day intervals between 50 and 250 days in milk. Cows lacking pregnancy confirmation data at 250 days-in-milk are now assumed to be open.

The new DPR measurements are much more accurate. The genetic trend for all breeds is estimated to be twice as large as before. Improvements in fertility management from the early 1960s until the year 2000 was not sufficient to keep up with the decline in genetic merit. From 2000 on, Holstein breeders have emphasized fertility in their breeding selections. That not only halted the long term decline, but the Holstein is the only breed to see a significant upturn in the DPR values.

The new DPR information utilizes the actual breeding info and conception rates more fully to determine the 21-day pregnancy rate. The change in definition of DPR has had an impact on not only the DPR values but also on several other traits and subsequently on our estimate of breed differences and the ranking of top animals. The new DPR values show a greater increase for the top Holstein genomic young bulls compared to their contemporaries from the Jersey breed.

The improved fertility and Productive Life (PL) evaluations now have a stronger relationship with an animal’s TPI® value. The new DPR value handles differences in voluntary waiting period much better. There’s less emphasis on early conception and more on conception rates throughout the lactation. Bulls whose daughters had a longer voluntary waiting period have seen an improvement in their DPR proof. For example, the DPR values on high type bulls like Atwood and Gold Chip have gone up. The first breeding of the daughters of these bulls would have been delayed to obtain a 365-day record. The DPR values of high-index bulls like Robust, Numero Uno, and Shamrock have also gone up. Some of their daughters were being flushed and would have had a longer voluntary waiting period.

All of this has led to a higher correlation with the TPI® values. The new DPR values are more highly correlated with Heifer Conception Rate (HCR), Cow Conception Rate (CCR), and Productive Life. We even see a slight increase with production, giving us an overall increase correlation between the new DPR values with TPI®.

Many breeders were surprised to see the higher relationship among the top TPI® animals and their corresponding high fertility values. Part of the explanation of this change is an increase in the spread, or range (Standard Deviations), of the PTAs for all of the fertility traits, as well as Productive Life. Adjusting the Standard Deviations of the traits used in the TPI® formula will move some emphasis from the fertility traits over to the production traits. This comes closer to the original TPI® formula changes announced this summer.

The Genetic Advancement Committee of the Holstein Association USA, Inc. (HAUSA), met on December 17 to discuss the December genetic evaluation changes and recommended an adjustment to the Standard Deviations used in the TPI® formula. The implementation plan, approved by the HAUSA board of directors on December 18, is:

Implementation Plan:

  • The current December 2014 TPI® values will remain official until the next full genetic evaluation update in April 2015.
  • New Standard Deviations will be used in April 2015 to account for the increased spread created by the new DPR definition.
  • The updated values of 2187 and 3.9 in the TPI® formula are being used to maintain the same genetic base and range as the current December 2014 TPI® values.

The complete TPI® formula with updated Standard Deviations, starting in April 2015, is as follows:

[27*PTAP +16*PTAF + 3*FE + 8*PTAT – 1*DF + 11*UDC + 6*FLC + 7*PL – 5*SCS + 13*FI – 2*DCE – 1*DSB] 3.9 + 2187 19 22.5 44 .73 1 .8 .85 1.51 .12 1.25 1 .9

Adjusting the TPI® formula for the new Standard Deviations will only have a small impact on TPI values and the ranking of top animals. For example, for the top 100 Genomic bulls, the average change is 1 TPI point when comparing the current TPI® values with the TPI® value using the new Standard Deviations. The average change up or down is 11 TPI points, so there is a little reshuffling or reranking. However, we will not alter the status of any of the top bulls or top cows; they are still top animals.

Announcing the April 2015 TPI® formula now will help breeders to better plan their future purchasing, breeding, and mating decisions.

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