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Zoetis Expands Genetics Portfolio With Calf Wellness Traits in Clarifide® Plus

Zoetis announced the addition of three calf wellness traits to Clarifide® Plus for Holsteins. The new calf wellness traits include calf livability, respiratory disease and scours. This dependable genetic information enables dairy producers to genetically improve calf health and survival within their herds, as the calf wellness trait information helps identify and select for calves more likely to survive as well as animals that are less likely to become ill due to respiratory disease and scours. Minimizing disease risk improves calf health, results in fewer treatments and lowers calf mortality — all important animal well-being considerations for producers.

As part of the offering with Clarifide Plus, the Calf Wellness Index (CW$) is a multitrait selection index that exclusively focuses on calf wellness traits to directly estimate the potential profit contribution of the calf wellness traits for an individual animal.

In addition, CW$ has been added to the Dairy Wellness Profit Index® (DWP$®) to supplement the most comprehensive animal ranking selection available commercially in Holsteins. DWP$ includes all Zoetis wellness traits for cows and calves. Plus, DWP$ includes other economically important production, performance and longevity-related traits. The inclusion of calf wellness traits creates an opportunity for producers to realize part of the lifetime economic gains earlier in life — as early as near birth — occurring approximately nine months after implementing breeding selecting strategies. DWP$ helps improve the outcome of the calf wellness traits with their inclusion, thus improving their progress toward enhancing overall herd health.1

Importance of Calf Wellness

Heifer replacement costs are often the second-highest expense on dairy farms, averaging from 8.6% up to 20% of total production cost in Holstein herds.2,3 This cost is heavily influenced by many factors, including disease incidence and calf mortality.

“Calf health and mortality can mean the difference between profits or shortfalls in tight margin years,” said Kent Weigel,* PhD, professor and chair of the Department of Dairy Science at University of Wisconsin-Madison. “We completed research that published 10 years ago, showing genetic differences between sire families and their chances of developing health challenges like milk fever** or mastitis. It was encouraging to see Zoetis use this research to develop Clarifide Plus, a tool producers can use for making genetic selection decisions to raise animals with reduced risk for health problems. Now Zoetis has taken a step farther to introduce calf wellness traits that help minimize disease risk for respiratory disease and scours, which will be game-changing for producers.”

Reports demonstrate the impact on U.S. dairies from scours and respiratory disease — the leading causes of calf death loss and disease in the first year of life:

  • 23.9% of pre-weaned dairy heifers are affected by scours.
  • 12.4% of pre-weaned dairy heifers are affected by respiratory disease.
  • 56% of all pre-weaned calf deaths are due to scours.
  • 47% of all weaned calf deaths are due to respiratory disease.4

The cost of calf health presents significant and long-lasting challenges. For example, records show that calves with respiratory disease that required treatment produced about 1,087 pounds less milk in the first lactation than calves with no record of being treated.5

The impact from disease can present lifelong setbacks, such as with calves impacted by pneumonia during the first 90 days of life, which are more likely to experience increased age at first calving, higher incidence of dystocia, lower milk production and greater mortality before first calving.6 Other studies have indicated 2 to 2.5 times greater risk of death before calving for animals that had either pneumonia or scours, respectively.7,8

Clarifide Plus was the first commercially available genetic evaluation for wellness traits for U.S. Holsteins, launched in March 2016. In addition to the new calf wellness traits — calf livability, respiratory disease and scours — Clarifide Plus provides reliable genomic predictions to help producers manage and reduce risk for mastitis, lameness, metritis, retained placenta, displaced abomasum and ketosis. Clarifide Plus provides accurate genetic predictions using cutting-edge genetic evaluation methodology applied to data collected from U.S. commercial production settings. This results in an average reliability of 50% or more for the six cow wellness traits9 and 39% reliability for the average of the three calf wellness traits on young genomic-tested calves.1

“Genomic predictions for wellness traits were developed because of the commitment Zoetis has to the overall health of dairy cattle,” said Cheryl Marti, associate director, U.S. Marketing, Dairy Genetics and Reproduction, Zoetis. “We strive to improve dairy wellness and understand genetic factors impacting resistance to common diseases. The recently announced development of the first Holstein reference genome at Zoetis allowed us to map regions of the genome influencing disease outcomes in calves. These discoveries will lead to improvements in the reliability of future predictions for Dairy Wellness.”

The calf wellness trait information helps dairies obtain the full lifetime value of healthier calves by selecting and breeding for animals that have a better chance of becoming healthy, productive cows, thus better positioned to attain their genetic potential — and increase a dairy operation’s profitability.

Zoetis recognizes that every dairy has different strategies as well as information, management and support needs. For this reason, Zoetis has a broad portfolio of genomic testing solutions including Clarifide Plus, Clarifide, Clarifide® Ultra and Clarifide® Core.

About Zoetis
Zoetis (NYSE: ZTS) is the leading animal health company, dedicated to supporting its customers and their businesses. Building on more than 60 years of experience in animal health, Zoetis discovers, develops, manufactures and markets veterinary vaccines and medicines, complemented by diagnostic products, genetic tests, biodevices and a range of services. Zoetis serves veterinarians, livestock producers and people who raise and care for farm and companion animals with sales of its products in more than 100 countries. In 2017, the company generated annual revenue of $5.3 billion with approximately 9,000 employees. For more information, visit www.zoetisUS.com.

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